Mariners vs Astros Prediction, Picks, and Odds for Tonight’s MLB Game

Despite Seattle's latest hot stretch, the Mariners continue to strike out at an alarming rate. Find out how this affects tonight's AL West handicap when Ronel Blanco takes the mound in our Mariners vs. Astros betting picks.

Kenny Ducey - Contributor at Covers
Kenny Ducey • Betting Analyst
May 3, 2024 • 15:39 ET • 4 min read
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This article contains predictions for an old game!

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Ronel Blanco Houston Astros MLB
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The Seattle Mariners’ offense struggles have been well documented this season, but a recent stretch has seen them win five out of their last seven games.

Seattle will now head to Houston, where it has had a great deal of trouble over the years. Find out how this affects our Mariners vs. Astros predictions and MLB picks on Friday, May 3.

Mariners vs Astros prediction

My best bet
Astros moneyline (-112 at FanDuel)

My analysis

Despite their latest run of wins, the Seattle Mariners remain a middling group offensively. In fact, they've posted a very poor 76 wRC+ over the last week and have relied on their excellent pitching to get them into the win column.

Seattle has done well to look even worse at the plate during this hot streak, striking out in an unsightly 33.8% of plate appearances. The M's now run into Houston Astros right-hander Ronel Blanco, who has struck out six or more in three of his five starts.

On the flip side, George Kirby will once again be asked to pitch exceptionally if the Mariners want to have any chance tonight. Like many of Seattle’s arms, he’s an extreme fly-ball pitcher. While that tends to work inside the friendly confines of T-Mobile Field, the home/road splits continue to be damning for the young right-hander.

Kirby owns a 5.00 ERA in two road starts this year and his ERA is now 0.81 runs higher away from Seattle for his career. The Astros hold great marks against power pitchers like Kirby and on the whole have looked so much better offensively since eliminating Jose Abreu from the equation, ranking second in wRC+ over the last week of play. 

I like Houston to get to Kirby and ride Blanco to the win.

Mariners vs Astros same-game parlay (SGP)

Astros moneyline

Ronel Blanco 7+ strikeouts

Joey Loperfido 2+ total bases

Right-handed starters have struck out seven or more Mariners in five of their last six starts, and Blanco himself has hit this number twice this season, including last time out in Colorado, where he recorded eight in 5 2/3 frames. Seattle is punching out nearly 34% of the time over the last week and I expect this trend to continue at Minute Maid Park tonight.

I'll also take touted rookie Joey Loperfido to continue his hot start at the big-league level. The rookie has feasted on right-handers to start his MLB career and is slashing .382./.488./588 as a whole. 

Learn how to bet a same-game parlay with these helpful tips and strategies.

Mariners vs Astros odds

Mariners vs Astros live odds

Mariners vs Astros opening odds

  • Run line: Seattle +1.5 (-210) | Houston -1.5 (+160)
  • Moneyline: Seattle +100 | Houston -120
  • Over/Under: Over 8.5 (-105) | Under 8.5 (-125)

Mariners vs Astros spread and Over/Under analysis

  • The Astros opened up around -120, but this game has quickly settled in close to a pick'em.
  • The Mariners have accounted for just 34% of the cash wagered on the moneyline at DraftKings, compared to 47% of the bets.
  • The total has fallen from the opening line of 8.5 to 8.0 as of writing, with steady action on the Under.
  • The Under has been a favorite of bettors, taking on 80% of tickets and 95% of the handle.

Mariners vs Astros trend

The Astros have covered the first five innings run line in 10 of their last 15 games (+5.21 Units / 31% ROI). Find more MLB betting trends for Mariners vs. Astros

Mariners vs Astros game info

Location: Minute Maid Park, Houston, TX
Date: Friday, 5-3-2024
First pitch: 8:10 p.m. ET
TV: Root Sports, Space City Network
Mariners starting pitcher: George Kirby
(3-2, 4.18 ERA)
Astros starting pitcher: Ronel Blanco
(3-0, 1.65 ERA)

Mariners vs Astros latest injuries

Mariners vs Astros weather

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Kenny Ducey - Covers
Betting Analyst

Kenny Ducey has worked in sports media for more than 10 years and began his journey as a credentialed reporter with Fordham University's WFUV Sports before moving on to Sports Illustrated. There, he wrote about baseball, basketball, and tennis - twice covering the NBA Finals.

He's been in the betting space for seven years, and has established himself as a top expert in MLB and tennis handicapping with brands like Tennis Channel, NBC Sports, and DraftKings. He's also been a frequent guest on betting shows such as MLB's Bettor's Eye and Tennis Bets Live.

Kenny has a knack for identifying underappreciated pitchers and tennis players as moneyline underdogs and credits his unique data analysis and hours of watching sports as the biggest reasons for success through the years. His best advice to bettors? Watch the games, trust your eye, and always question the public narrative.

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