It's Jacob Misiorowski day, which means the Milwaukee Brewers are predictably monstrous -260 moneyline favorites.
With a massive pitching advantage, my Cubs vs. Brewers predictions and MLB picks are attacking the Brewers on the run line.
Who will win Cubs vs Brewers today: Milwaukee Brewers -1.5 (-115)
The Milwaukee Brewers have advantages everywhere in this game.
They’ve had a more potent offense than the Chicago Cubs over the course of the season, and the recent numbers are better as well.
Milwaukee ranks fourth in wOBA and OPS against right-handed pitching in June. Even with recent improvements, Chicago sits 16th and 18th over the same period.
The Brewers have a massive pitching edge with Jacob Misiorowski starting opposite Colin Rea. Misiorowski ranks in the 100th percentile in Pitcher Run Value and has allowed only three earned runs over his last nine starts.
Back Milwaukee on the RL to -135.
COVERS INTEL: Colin Rea ranks in the 10th percentile in xERA.
Cubs vs Brewers Over/Under pick: Under 7.5 (-125)
Misiorowski has allowed 0.33 runs per start since May 1, making it impossible for any offense to get going in the slightest.
He faced the Cubs during that stretch and pitched six innings of shutout ball while striking out eight batters. Predictably, that game went Under 7.5 runs.
I don’t see the Cubs scoring more than a run or two here, which puts a lot of pressure on the Brewers to score in bulk.
I expect a 5-1 type of game, and see plenty of value on an Under of 7.5 runs. Bet to -140.
- ML/RL bets: 42-31, +2.20 units
- Over/Under bets: 38-31-4, +3.24 units
Cubs vs Brewers weather
Clear to partly cloudy skies are expected tonight with temperatures dipping into the mid-fifties tonight.
Cubs vs Brewers odds
- Moneyline: Cubs +210 | Brewers -260
- Run line: Cubs +1.5 (+100) | Brewers -1.5 (-120)
- Over/Under: Over 7.0 (-125) | Under 7.0 (+105)
Cubs vs Brewers trend
Milwaukee has hit the run line in 23 of the last 40 home games (+10.25 units, 22% ROI). Find more MLB betting trends for Cubs vs. Brewers.
How to watch Cubs vs Brewers and game info
| Location | American Family Field, Milwaukee, WI |
| Date | Friday, June 26, 2026 |
| First pitch | 7:45 p.m. ET |
| TV | Apple TV |
| Cubs starting pitcher | Colin Rea (5-5, 4.99 ERA) |
| Brewers starting pitcher | Jacob Misiorowski (8-3, 1.45 ERA) |
Cubs vs Brewers latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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