The Milwaukee Brewers and St. Louis Cardinals begin a four-game set at Busch Stadium tonight, with the two NL Central foes trading at even -110 odds ahead of the series opener.
My top Brewers vs. Cardinals predictions and MLB picks are calling for Milwaukee to secure a high-scoring win tonight.
Who will win Brewers vs Cardinals today: Brewers moneyline (-103)
The Milwaukee Brewers have the highest xwOBA and are averaging 5.1 runs per game over the past 30 days, and they also rank fifth in wOBA against righties for the season.
So, with St. Louis Cardinals starter Dustin May allowing a healthy 46.3% hard-hit rate, I’m confident in the Brewers putting enough runs on the scoreboard to pull away tonight.
Milwaukee ranking fourth in walk rate and third in on-base percentage against righties will make it all the more difficult for May to navigate the Brew Crew bats, too.
This Brewers moneyline is in play down to -105 for me.
COVERS INTEL: The Brewers rank second in the majors with a 36-23 record against right-handed starting pitchers.
Brewers vs Cardinals Over/Under pick: Over 8.5 (+114)
Pair the highlighted strength of the Milwaukee offense with St. Louis also ranking third in xwOBA over the past 30 days and for the season, and we’ve got a perfect recipe for an Over. The Cards have averaged 5.2 runs per game during the stretch, too.
Brewers lefty Shane Drohan has also allowed an above-average .338 wOBA while pitching to a mediocre 4.09 ERA across 33 innings as a starter this season.
Finally, the Brewers and Cardinals respectively rank 27th and 25th in bullpen xFIP across the past two weeks, so this Over has my attention down to +100.
- ML/RL bets: 40-18, +24.41 units
- Over/Under bets: 17-14, +1.85 units
Brewers vs Cardinals weather
The forecast at Busch Stadium calls for comfortable, clear conditions in the mid-70s with minimal humidity and light 5 mph winds to have a limited impact on playing conditions.
Brewers vs Cardinals odds
- Moneyline: Brewers -110 | Cardinals -110
- Run line: Brewers -1.5 (+150) | Cardinals +1.5 (-175)
- Over/Under: Over 8 (-115) | Under 8 (-105)
Brewers vs Cardinals trend
The Brewers have won 33 of their last 50 games for +9.30 units and a 12% ROI. Find more MLB betting trends for Brewers vs. Cardinals.
How to watch Brewers vs Cardinals and game info
| Location | Busch Stadium, St. Louis, MO |
| Date | Monday, July 6, 2026 |
| First pitch | 7:45 p.m. ET |
| TV | Brewers.TV, Cardinals.TV |
| Brewers starting pitcher | Shane Drohan (3-2, 3.12 ERA) |
| Cardinals starting pitcher | Dustin May (5-6, 4.80 ERA) |
Brewers vs Cardinals latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
