Kayla Harrison vs Amanda Nunes Prediction, Picks & Odds: UFC 334 in New York City

Danny Howard - Contributor at Covers.com
Danny Howard • Betting Analyst 21+ years betting experience
Updated: Nov 13, 2026 , 01:56 PM ET • 4 min read

Harrison was supposed to inherit Nunes' throne. The Lioness isn't coming back to hand it over.

Kayla Harrison vs Amanda Nunes Fight Predictions
Photo By - Reuters Connect. Kayla Harrison and Amanda Nunes.

Kayla Harrison is a 62% favorite against Amanda Nunes on Saturday's UFC 334 card at Madison Square Garden in New York, according to UFC odds.

My Kayla Harrington vs. Amanda Nunes predictions and free betting picks for this championship showdown on Nov. 15 back the challenger to pull off the upset win in her first fight since 2023.

Kayla Harrison vs Amanda Nunes predictions for UFC 334

Market Pick
Who will win  Amanda Nunes
Top pick Amanda Nunes to win
Prop Amanda Nunes by decision
Combo 2.32x
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Who will win Kayla Harrison vs Amanda Nunes: Nunes

Amanda Nunes is my pick to 42%.

Kayla Harrison is a frightening grappler, but her striking remains rudimentary compared to that of the former two-division champion. 

Nunes has the defensive wrestling, Brazilian jiu-jitsu background, and superior striking to make the champion uncomfortable. Her lengthy retirement is concerning, but Harrison is also returning from a significant layoff following neck surgery. 

If Nunes still has something left in the tank, I expect her experience and deeper offensive arsenal to carry her to an upset.

Kayla Harrison vs Amanda Nunes top pick: Nunes to win

Harrison has overwhelmed opponents with her wrestling and top control, but Larissa Pacheco demonstrated she can be beaten when an opponent survives those exchanges and makes her pay on the feet.

Nunes is a considerably more accomplished striker and owns 82% takedown defense, giving her the tools to frustrate Harrison's preferred approach.

The two formerly trained together, so neither should be unfamiliar with the other's strengths. Nunes hasn't competed since 2023, but Harrison has been sidelined since June 2025.

I'm trusting the former champion's experience, defensive grappling, and superior striking to overcome Harrison's physicality.

Covers COVERS INTEL: Nunes has an 82% takedown-defense rate, while 53% of Harrison's significant strikes in the UFC have come from the ground.

Kayla Harrison vs Amanda Nunes prop: Nunes by decision

The champ is a durable, physically imposing grappler who won't be easily overwhelmed, but Nunes has the defensive skills to survive tough exchanges and get back to her feet.

I expect the challenger to favor her superior striking rather than unnecessarily chase a finish after such a long layoff. If she can consistently frustrate Harrison's wrestling, her cleaner punches and experience should carry her to a competitive decision.

Kayla Harrison vs Amanda Nunes combo

  • Amanda Nunes moneyline
  • Amanda Nunes to win inside the distance - No

Harrison is a tremendous grappler, but her striking remains a significant weakness against someone with Nunes' experience and offensive versatility.

Nunes has the defensive wrestling to make Harrison work for every takedown, and her superior striking should give her opportunities to land the cleaner, more meaningful shots.

The champs' strength and conditioning will make this competitive, but I'm trusting Nunes to survive the grappling exchanges, establish her offense, and win enough rounds to take the title.

Kayla Harrison vs Amanda Nunes odds

For help understanding probabilities, see our odds calculator.

Method of Victory Kayla Harrison Amanda Nunes
To win outright 62% 39%
To win by KO/TKO 9% 23%
To win by decision 20% 13%
To win by submission 28% 3%
Fight to go the distance Yes
37%
No
63%

Odds as of 11-13.

Nunes is the underdog, but her skillset makes her a valuable one at that. Nunes only has four submission victories, which is why her odds to win are priced so low. A decision win (13%) holds the most value.

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Kayla Harrison vs Amanda Nunes tale of the tape

Kayla Harrison   Amanda Nunes
36 Age 38
5-foot-8 Height 5-foot-8
Bantamweight Weight Class Bantamweight
66 inches Reach 69 inches
19-1 Record 23-5
6 Wins by KO 13
8 Wins by submission 4

Harrison and Nunes are identical in height, but Nunes holds a three-inch reach advantage and considerably more experience against elite UFC competition.

Nunes has recorded 13 knockouts in 23 victories compared to Harrison's six in 19 wins, while Harrison owns the stronger submission résumé. Nunes is two years older and returning from retirement, but her superior striking and defensive grappling should give her the tools to challenge the champion.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Danny Howard - Covers.com
Betting Analyst

After a decade of covering all things boxing, from recapping the sport’s biggest fights to sharing behind-the-scenes details of the sweet science, Danny found himself immersed in sports betting, focusing on the sports he knows best. As a boxing and MMA contributor with seasoned experience from growing up around each sport, he can uncover the nuances and intangibles that can make the difference between victory and defeat.

Danny’s work has been mentioned on ESPN and USA Today, and he was a featured guest on The Esportz Network podcast, where he shared his combat sports insights. He is also a published author, with his novel And Stay Down! Boxing’s Worst Comebacks available on Amazon.

Danny is always on the lookout for the best odds and props when it comes to fight night, with Draft Kings and BetMGM being his go-to sites. Danny’s approach to finding value in the theater of the unexpected hinges on the fighters' recent form, especially when considering props.

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