Week 8 arrives with storylines sharpened and stakes clarified. Contenders are separating through depth, discipline, and adaptable game plans while pretenders are confronting film that tells the truth.
There are a lot of moving parts, which is why we turned to artificial intelligence to make sense of it all.
Using the Week 8 moneyline odds from FanDuel, we asked ChatGPT to pick the straight-up winners of every single game on the schedule from the opening whistle on Thursday night to the final play on Monday.
Here’s how the AI sees Week 8 shaking out with its NFL picks.
Week 8 NFL moneyline picks
| Matchup | Pick |
|---|---|
 Vikings vs  Chargers |
-184 |
 Jets vs  Bengals |
-320 |
 Bears vs  Ravens |
-310 |
 Dolphins vs  Falcons |
-420 |
 Browns vs  Patriots |
-360 |
 Giants vs  Eagles |
-405 |
 Bills vs  Panthers |
-370 |
 49ers vs  Texans |
+100 |
 Buccaneers vs  Saints |
-220 |
 Cowboys vs  Broncos |
-174 |
 Titans vs  Colts |
-1200 |
 Packers vs  Steelers |
+146 |
 Commanders vs  Chiefs |
-820 |
Lines courtesy of FanDuel.
Vikings vs Chargers: Chargers (-184)
Los Angeles returns home for a needed reset and gets the dome benefit against a Minnesota team that has been volatile in late-game situations. The Bolts’ offense should find enough balance to protect a modest favorite price. I’m siding with the home field and the better red-zone profile to carry the day.
Jets vs Bengals: Bengals (-320)
Cincinnati’s offense has rediscovered rhythm and should be able to sustain drives against a Jets unit that’s leaned on the defense far too much. Lay the moneyline with the home side if you want to avoid the spread hook.
Bears vs Ravens: Ravens (-310)
Back at home and laying a clear favorite tag, Baltimore projects to control the trenches and dictate pace. Chicago’s recent improvements are real, but the Ravens’ defensive ceiling and situational edges at home push this toward chalk.
Dolphins vs Falcons: Falcons (-420)
Atlanta has home field in the dome and the market backing to match — FanDuel lists it as a robust moneyline favorite. Miami enters Week 8 in a form slump that has drawn public scrutiny from head coach Mike McDaniel after a lopsided loss, and the Dolphins’ offense has struggled to sustain drives.
In a controlled indoor environment, Atlanta’s balanced approach and situational steadiness should travel, while the betting price implies a clear win probability edge for the Falcons.
Browns vs Patriots: Patriots (-360)
New England is a solid home favorite for a reason: the market expects its defense and game management to control pace and field position at Gillette. The Browns have been priced as clear underdogs all week, reflecting questions about their offensive consistency on the road.
At roughly -360, the line implies around a 78% win probability for the Patriots, which matches the spread (-7) and the consensus view that New England’s situational strengths (third down, special teams, late-game execution) tilt the matchup. In short: the price says Patriots, and the setup (home, style, consistency) supports it.
Giants vs Eagles: Eagles (-405)
Philadelphia’s margin for error at home is sizable. Expect the Eagles to control the line of scrimmage and bully their way to a methodical win. Consider ML as an anchor leg in parlays given the heavy juice.
Bills vs Panthers: Bills (-370)
Buffalo’s firepower and drive efficiency profile justify the large number in a matchup where one or two splash plays can end it early. If you’re price-sensitive, consider pairing this ML in a two-leg moneyline parlay.
49ers vs Texans: 49ers (+100)
Priced near a pick’em, this is about trust in San Francisco’s coaching and late-game execution. The Niners’ front can squeeze Houston’s run game and force uncomfortable down-and-distance. At even money, I’ll ride with the Niners.
Buccaneers vs Saints: Buccaneers (-220)
Even on a short week, Tampa’s overall efficiency, and the matchup against a New Orleans offense that’s been inconsistent, support the favorite. The Bucs’ defense should create extra possessions and shorten the field.
Cowboys vs Broncos: Broncos (-174)
Denver has home-field edge at altitude and the market’s backing at roughly a field-goal spread and sub-200 moneyline. FanDuel-listed prices imply the Broncos’ defense (Top-10 vs. the pass by yardage allowed) can keep a lid on explosive plays while their offense capitalizes on a shaky Dallas run defense.
In a likely high-total game, situational advantages (crowd, familiarity with thin air, scripted starts) tip toward the home side. I’m siding with the favorite at Mile High.
Titans vs Colts: Colts (-1200)
The number tells the story: Indianapolis owns sizable advantages on both lines and a high-leverage red-zone edge. The price limits single-bet utility; parlay legs only.
Packers vs Steelers: Steelers (+146)
Pittsburgh’s defense at home on a prime-time stage is a tough landing spot. Expect a field-position battle where the Steelers’ pressure generates the game’s turning point. I’m laying the ML with the AFC North leaders.
Commanders vs Chiefs: Chiefs (-820)
Arrowhead in prime time is a tall order for a Washington team with its own offensive questions. Kansas City’s scripted starts and situational mastery (third down/red zone) should be enough to build and protect a multi-score lead.
ChatGPT has gone 73-34 so far this season for +32.36 units.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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