NFL Player Prop Picks: Week 17 Best Bets

Derrick Henry has been on a roll over the last few weeks, and with Lamar Jackson out of the picture on Saturday, expect another heavy workload from the Ravens running back.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Dec 26, 2025 • 16:59 ET • 4 min read
Derrick Henry Baltimore Ravens NFL
Photo By - Imagn Images. Baltimore Ravens running back Derrick Henry (22).

It’s the second-to-last week of the NFL regular season, and we have some intriguing matchups on the board.

My NFL picks expect Baltimore to lean on Derrick Henry on Saturday night, while the Bears will contain Christian McCaffrey through the air on Sunday Night Football.

Here are my top NFL player props for Week 17.

NFL Week 17 prop picks

Player Pick FanDuel
Texans Danielle Hunter To Record a Sack - Yes -160
Ravens Derrick Henry Over 16.5 rushing attempts -102
Cardinals Jacoby Brissett  Over 37.5 passing attempts -114
Saints Tyler Shough Over 221.5 passing yards -114
49ers Christian McCaffrey Under 42.5 receiving yards -114
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Best Bets and NFL Player Props for Week 17

Prop pick: Danielle Hunter to record a sack

-160 at FanDuel

Houston Texans edge rusher Danielle Hunter was the league's biggest Pro Bowl snub this year. Hunter ranks fourth in the NFL with 13 sacks and fifth in pressures (75). He should thrive against the Los Angeles Chargers, who have surrendered 51 sacks due to multiple injuries at tackle.

Left tackle Rashawn Slater has missed the entire year, while stud sophomore Joe Alt hit the IR in November. Jamaree Salyer was holding down the blindside but got injured last week and is ruled out for Week 17.

Hunter usually lines up on the right side, giving him a juicy matchup against whoever the Bolts are forced to play at LT. He’s recorded at least half a sack in five of his last seven games and should pressure Justin Herbert on Saturday.

Prop pick: Derrick Henry Over 16.5 rushing attempts

-114 at FanDuel

The Baltimore Ravens will start backup quarterback Tyler Huntley on Saturday night as they fight for their playoff lives. Expect Baltimore to take pressure off their backup by relying on Pro Bowl running back Derrick Henry.

Henry has logged at least 18 carries in eight of his last 10 games, including Huntley’s previous start this season when he rushed 21 times for 71 yards versus the Bears in Week 8.

The 247-pound sledgehammer thrives in cold-weather games late in the season and has topped 90 yards in his previous three outings. He should see plenty of work against a Green Bay Packers defense that has allowed 29.8 rush attempts per game over the last four weeks.

Prop pick: Jacoby Brissett Over 37.5 passing attempts

-114 at FanDuel

Arizona Cardinals quarterback Jacoby Brissett had been a money-making machine until last week’s hiccup.

Before that poor outing, Brissett had surpassed his passing yards total in each of his first nine starts and recorded 40+ pass attempts in his previous six games. Expect a bounce-back performance on Sunday against the Cincinnati Bengals.

Cincinnati ranks dead last in the NFL in defensive dropback success rate, giving Brissett plenty of room to move the ball through the air. The Bengals are also 7-point favorites, which could create a negative game script for Arizona, though the Cardinals have been passing at an extremely high rate even in neutral situations.

Prop pick: Tyler Shough Over 221.5 passing yards

-114 at FanDuel

Expect a push for Offensive Rookie of the Year from New Orleans Saints QB Tyler Shough.

The second-round pivot didn’t start until Week 8, but Shough has come on strong down the stretch. He’s thrown for more than 235 yards in five of his previous six games and is coming off a career-high 308-yard performance against the Jets.

Shough has a favorable matchup on Sunday against the Tennessee Titans, who rank 27th in defensive pass DVOA. The Titans benefitted from facing a third-string QB last week, but they had allowed 275.4 passing yards per game in their previous seven contests.

Prop pick: Christian McCaffrey Under 42.5 receiving yards

-114 at FanDuel

Christian McCaffrey was initially on pace to shatter the NFL record for receiving yards by a running back, but he has slowed down over the last few weeks.

Through the first 12 games of the year, McCaffrey averaged 65.4 receiving yards per game. However, he hasn’t cracked the 30-yard mark in his last three games, averaging just 21.3 yards per outing during that span.

It isn’t that McCaffrey has played poorly; the San Francisco 49ers’ previously banged-up receiving corps is now healthy. With a plethora of dangerous targets for Brock Purdy, McCaffrey is seeing fewer opportunities.

C-Mac will be limited in the passing game by a Chicago Bears defense that has allowed the third-fewest receiving yards per game (24.2) to opposing running backs.

NFL Week 17 prop betting card

  • Hunter to record a sack (-160)
  • Henry Over 16.5 rushing attempts (-202)
  • Brissett Over 37.5 passing attempts (-114)
  • Shough Over 221.5 passing yards (-114)
  • McCaffrey Under 42.5 receiving yards (-114)

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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