Nebraska vs Oklahoma Picks and Predictions: It's Back to #FadeNebraska

The Cornhuskers have beaten up on lesser foes the past two weeks, and now have to face a CFP hopeful led by a legit Heisman candidate. Find out if they're up for the challenge as we break down our Nebraska vs. Oklahoma picks.

Chris Euksuzian
Last Updated: Sep 17, 2021 10:18 AM ET Read Time: 4 min
Spencer Rattler Oklahoma Sooners college football
Photo By - USA TODAY Sports

The Nebraska Cornhuskers didn’t have an ideal start to their season when they lost to Illinois. Since that loss, they have won their last two games by a combined score of 80-10!

Meanwhile, the Oklahoma Sooners once again have big expectations in one of their last seasons in the Big 12. The Sooners have a Heisman hopeful in Spencer Rattler, and they will go as far as he can take them.

Can Oklahoma continue their path to the CFP and handle the Cornhuskers?

Find out with our free college football betting picks and predictions for Nebraska vs. Oklahoma on Saturday, September 18.

Nebraska vs Oklahoma odds

Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.

The line opened up at most sportsbooks Oklahoma -22. At the time of the writing, the line has moved up to -22.5. The total opened up at 61.5 and it has gone up to 62 at most books.

Use the live odds widget above to track any future line movements right up until kickoff and be sure to check out the full college football odds before placing your bets.

Nebraska vs Oklahoma picks

Picks made on 9/16/2021 at 9:35 p.m. ET.
Click on each pick to jump to the full analysis.

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Nebraska vs Oklahoma game info

Location: Memorial Stadium, Norman, OK
Date: Saturday, September 18, 2021
Time: 12:00 p.m. ET

Nebraska vs Oklahoma betting preview


Be sure to monitor the gametime conditions with our NCAA football weather info.

Key injuries

Nebraska: Austin Allen TE (Questionable), Travis Vokolek TE (Questionable), Casey Rogers DL (Questionable), Oliver Martin WR (Questionable), Omar Manning WR (Questionable), Thomas Fidone II TE (Out), Will Honas LB (Out)
Oklahoma: Danny Stutsman LB (Questionable), Billy Bowman DB (Questionable), Woodi Washington (Doubtful), Brian Darby WR (Out), Nathan Rawlins-Kibonge DE (Questionable), Kendall Dennis DB (Questionable), Theo Wease WR (Out), Marcus Major (Out)
Find our latest NCAA football injury reports.

Betting trend to know

The Under is 6-2 in the last 8 meetings. Find more NCAA betting trends for Nebraska vs. Oklahoma.

Nebraska vs Oklahoma predictions

The Oklahoma Sooners came into this season as one of the most dangerous offenses in the entire country. They have lived to the hype, averaging 58 points on offense in their first two games. If you look beyond this season, Oklahoma has been dominant in the first half of games. In their last four games that have included top teams such as Florida and Iowa State, they have led at the half by an average of 25.75 points.

The Nebraska Cornhuskers have not been impressive this year. Nebraska has been on a slow start this season during the first half. The Cornhuskers averaged only 15 points per first half this season. The lone loss they had this season against Illinois, they were trailing at halftime. To make matters worse, Nebraska is 1-7 as dogs of more than four points vs. opponents off back-to-back straight up wins. Nebraska is a big underdog in this game. If they do not win, it will be because the Sooners dominated the first half.

These two teams are opposites when it comes to making a statement in the opening frame. I will take Oklahoma to take care of business early and cover the spread in the first half.

Both of these teams have put up plenty of points this season. The separation between these teams is more likely to come down to defense.

The Sooners defense has no weaknesses. It starts with the defensive line. This unit has already recorded eight sacks in just two games! Nebraska QB Adrian Martinez has already been sacked six times this season. He’s a mobile quarterback that tries to extend plays with his feet. With this ferocious line getting after the quarterback, it doesn’t suit Martinez's game well. Oklahoma's linebacker and defensive back groups are also one of the best in the nation. This defense is complete!

Despite its potential, Nebraska has had a hard time bringing that offense on the road. In their last five road games as an underdog, the Under has gone 5-0. The only time the Cornhuskers have gone Over the total this year was against Fordham at home. Nebraska had to score 52 points in that game to go Over the total. I can promise you, the Huskers won't produce that in Norman.

I see this game being very lopsided, enough where this game goes under the total.

NCAA parlays

Did you know that if you parlayed our Nebraska vs. Oklahoma picks, you could win $26.45 on a $10 bet?

Use our college football parlay calculator to create your own parlays and see their potential payouts.

Where can I bet on college football odds?

You can bet on college football odds at every online and casino sportsbook, including NCAA moneylines, spreads, Over/Under totals, and a ton of college football prop odds. Head over to our best football betting sites for the top spots to bet on college football odds in your area.

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