Week 14 College Football Picks: Brad Powers' Best Bets for Mississippi State, Illinois & More

NCAAF expert Brad Powers shares his favorite picks for Week 14 of the college football season.

Ryan Murphy - Managing Editor at Covers.com
Ryan Murphy • Managing Editor
Nov 25, 2025 • 10:55 ET • 4 min read
Illinois Fighting Illini quarterback Luke Altmyer (9) throws the ball against the Wisconsin Badgers.
Photo By - Imagn Images. Illinois Fighting Illini quarterback Luke Altmyer (9) throws the ball against the Wisconsin Badgers.

If you're hunting for college football Week 14 bets, this is the moment where the market moves faster than the scoreboard. Awards races swing on a single highlight, playoff odds wobble without a snap being taken, and coaching rumors ripple through locker rooms and lines alike. 

In a week stuffed with stakes and storylines, college football expert Brad Powers surfaces the numbers that matter, the narratives that move them, and the wagers with real edge. Check out his favorite NCAAF picks below.

Mississippi Mississippi vs Mississippi State Mississippi State best bet

Pick: Mississippi State +7.5 (-115 at FanDuel)

Powers' card opens with Mississippi State catching +7.5, a number he believes overstates the gap. The case blends power ratings with situational edges: a defense trending up against a predictable script, a quarterback who can extend plays against pressure, and a coaching staff that's leaned into tempo shifts at the right moments. When underdogs can muddy pace and limit explosive plays, the hook becomes equity - and the moneyline becomes more than a lottery ticket.

"Sprinkle a little bit on the moneyline. I think they're going to be live here," he says.

This is precisely the profile sharp bettors hunt: a live dog with a path to +2 turnover margin, field-position wins via special teams, and red-zone packages that convert drives into sevens, not threes. Market-wide, +7.5 is the inflection point where middling favorites must stack efficiency to separate. If they can't, fourth-quarter game states tighten, and that's where plus-money sprinkles cash.

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Northwestern Northwestern vs Illinois Illinois best bet

Pick: Illinois -6.5 (-122 at FanDuel)

The second play is Illinois -6.5, a spot where the market sits well below Powers' number. Even modest improvements in quarterback accuracy and early-down success rate can balloon value at sub-seven spreads, particularly if Illinois' defensive front dictates run fits and forces third-and-longs. That structural edge is what turns a single-possession favorite into a two-score outcome.

"This is my biggest disparity of the week," he explains. "We're laying the 6.5 with Illinois. I made it closer to 10."

Execution matters as much as conviction. Shop aggressively to capture the half-point under 7, scale your exposure to volatility, and set alerts for injury and weather updates. In a week where rumor and reality blur, the best closing line value often goes to the earliest, most prepared bettors.


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Heisman race volatility

The Heisman Trophy market has never felt more reactive. Momentum is minted overnight, and the distance between forgotten and favored can be one dazzling box score. Powers frames the dynamic bluntly, reminding bettors that a single Saturday can redefine the story voters and oddsmakers tell themselves.

"We live in an instant gratification society where, out of sight equals out of mind," he says.

Few examples capture that snapback effect better than Notre Dame's Jeremiah Love. A week ago, he sat at 40-1. One game later - eight carries, three touchdowns - his price compressed to as low as +350. The market didn't just take notice; it rewrote the script, rewarding explosive efficiency and the kind of score line that lights up social feeds, highlight shows, and ballots.

Even more telling: Indiana QB Fernando Mendoza rose to favorite status despite not playing. That juxtaposition of one player surging on minimal volume, another drifting upward in absentia, highlights how the Heisman is equal parts performance and perception.

When schedules stagger and media oxygen shifts, idle weeks can help or hurt a candidate depending on what competitors do and how the conversation evolves. For bettors, the lesson is timing: buy before a player's peak exposure, sell when narrative momentum outpaces résumé.

Playoff odds whiplash hits Mississippi

Playoff markets can be just as twitchy. Mississippi watched its price to make the field freefall from -3500 to -600 despite not taking the field. That kind of move isn't about yards or points; it's about uncertainty. Specifically, how instability at the top of a program changes expectations inside power-rating models and, just as importantly, in the minds of bettors and bookmakers.

"They were -3500 at this point last week," Powers says. "I said there's no way they can be -3500 with what's going on in that program."

When a number collapses on an idle team, it's a cue to dig for the source. Are the models updating opponents' form? Are tiebreakers shifting? Or is it a signal that the market believes off-field turbulence will bleed into prep and performance? Here, the latter drove sentiment.

Those willing to fade complacency and price in risk early were rewarded with a far more realistic number long before results could confirm the thesis.

The season's biggest disappointment

If volatility creates value, it also exposes mirages. Liberty opened as an even-money favorite to win Conference USA with a win total of 9.5. Now at 4-7 and eliminated from bowl contention, the Flames are the cautionary tale of 2024: a team whose preseason assumptions couldn't withstand injuries, matchups, and mounting pressure.

"Liberty was an even-money favorite to win the conference," Powers reflects. "Liberty's win total was 9.5. Right now, Liberty is 4-7. They're not going to a bowl game."

For bettors, Liberty's arc underscores two principles. First, numbers anchored to August can lag reality by Halloween if you cling to priors. Second, futures require exit plans. When a favorite shows early fragility (narrow wins against inferior opponents, defensive metrics slipping, quarterback efficiency dropping) consider hedging or selling positions before the market resets the price for you.

Conference championship scenarios and where the value hides

Conference championship week is where path analysis meets price. Boise State at +420 to win the Mountain West stands out as a classic scenario-based value: the probability of their reaching the title game and drawing a favorable matchup is higher than the implied odds, especially given how the league's top tier has cannibalized itself. When parity blurs the pecking order, deep and balanced rosters with stable quarterback play, special teams edges, and improving late-season efficiency become quietly underpriced.

The key with numbers like +420 is market positioning. Enter before tiebreakers and lookahead lines coalesce, then plan to create a synthetic middle in the championship game if the opponent opens as a short favorite. That way, you can hold a plus-money base ticket and still harvest value with a partial hedge on the other side, converting uncertainty into optionality.

Elsewhere, remember that leagues with compressed standings create bracket chaos. A single upset or injury report can flip home-field expectations and first-half totals. If your read is less about a dominant team and more about a favorable bracket, isolate the team whose path is least punishing and whose coaching staff has demonstrated in-season adaptability. Those are the portfolios that pay in December.

How narratives shape markets, and how to bet them

The common thread across Heisman futures, playoff odds, and late-season spreads is not just performance; it's the narrative velocity around it. Love's surge and Mendoza's idle ascension show how attention reallocates price. Mississippi's plunge without playing reveals how whispers of coaching change can be as loud as a loss. If you can anticipate the next storyline before it hardens into consensus, you can buy yesterday's number at tomorrow's price.

In practical terms, build a two-track process: numbers first, narratives second. Start with independent power ratings and path probabilities. Then layer the intangibles like press conference tone shifts, contract leaks, and travel or scheduling quirks that sap focus. When both tracks point the same direction, act early. When they diverge, reduce stake size or wait for steam to reveal where you're gaining the most edge.

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Ryan Murphy Managing Editor at Covers
Managing Editor

Ryan Murphy began his love affair with sports journalism at the age of nine when he wrote his first article about his little league baseball team. He has since authored his own weekly column for Fox Sports and has been a trusted voice within the sports betting industry for the past eight years with stops at XL Media and Churchill Downs. He’s been proud to serve as Managing Editor at Covers since 2022.

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