Looking for college football touchdown predictions and picks for Week 3?
Ryan Coleman-Williams is our top play, while Florida-Auburn offers plus-money value on Micah Mays Jr. and Jeremiah Cobb.
Here are the best touchdown plays and college football picks for Week 3.
Best Week 3 college football anytime touchdown picks
| Pick |  Odds |
|---|---|
 Ryan Coleman-Williams |
-110 |
 Jeremiah Cobb |
+110 |
 KJ Duff |
-105 |
 Kevin Jennings |
+245 |
 Micah Mays |
+390 |
Pick #1: Ryan Coleman-Williams -110
Alabama’s offense ranks 28th nationally in success rate at 52.9%, while Florida State’s defense ranks 103rd in net EPA per play and allows +0.20 EPA per play.
That should create consistent scoring opportunities for Alabama, particularly if the Crimson Tide controls field position. Ryan Coleman-Williams enters this matchup after a 130-yard performance and offers the explosive receiving ability needed to capitalize on Florida State’s defensive weaknesses.
Alabama’s defense also ranks 13th in net EPA, increasing the likelihood of short fields and extra possessions. At -110, Coleman-Williams needs to score in roughly 52.4% of outcomes to break even.
- Matchup: Alabama vs Florida State
- Date/Time: Saturday, Sept. 19 at 3:30 p.m. ET
- Location: Bryant-Denny Stadium, Tuscaloosa, Alabama
- TV: ABC
Pick #2: Jeremiah Cobb +110
Jeremiah Cobb leads Auburn with 24 carries and 138 rushing yards through two games, including a touchdown in the season opener. Auburn’s offense has struggled with efficiency, but Florida’s defense ranks only 89th nationally in net EPA per play.
Florida’s offense should also force Auburn to remain aggressive, creating opportunities for Cobb to stay involved throughout the game. His workload gives him the clearest path to a touchdown among Auburn players, and his role should be especially valuable near the goal line.
At +110, Cobb offers value as Auburn’s primary rushing threat.
- Matchup: Florida vs. Auburn
- Date/Time: Saturday, Sept. 19 at 7:00 p.m. ET
- Location: Jordan O'Hare Stadium, Auburn, Alabama
- TV: ESPN
Pick #3: KJ Duff anytime touchdown -105
KJ Duff is Rutgers’ best offensive weapon and should benefit from the game script against a heavily favored USC team.
Rutgers' offense has not been good, but it's almost entirely him providing it; in addition, USC’s defense has allowed +0.158 EPA per play, ranking 80th.
The Trojans also rank only 67th in defensive success rate.
Duff has 333 receiving yards and five touchdowns through three games.
If Rutgers falls behind, quarterback AJ Surace should be forced to throw more, giving Duff more opportunities against a defense that hasn't been particularly efficient.
- Matchup: USC vs. Rutgers
- Date/Time: Saturday, Sept.19 at 3:30 PM E.T.
- Location: Shi Stadium
- TV: CBS
Pick #4: Kevin Jennings anytime touchdown +245
Kevin Jennings is a strong longshot because SMU’s offense has been one of the most efficient units in this matchup. The Mustangs have generated +0.284 EPA per play, ranking 28th nationally, with a 56.7% success rate, ranking 15th.
Louisville’s defense ranks 89th in EPA per play allowed and 77th in defensive success rate. Head Coach Jeff Brohm is winless against SMU and has struggled against mobile QBs throughout his tenure at Louisville, which is probably why he's failed to beat the stud QB.
Jennings threw five touchdown passes last week and remains a legitimate rushing threat when Louisville’s pass rush forces him to improvise. The game total is near 60 points, and the close spread should keep SMU aggressive for four quarters. Jennings can score on a designed run, scramble or short-yardage play.
- Matchup: Louisville vs. SMU
- Date/Time: Saturday, Sept. 19 at 3:30 PM E.T.
- Location: L&N Federal Credit Union Stadium, Louisville, Kentucky
- TV: ESPN2
Pick #5: Micah Mays +390
Florida ranks second nationally in net EPA per play and sixth in offensive success rate at 58.2%, while Auburn’s defense ranks 113th in net EPA per play and 114th in success rate allowed.
That creates a strong environment for Florida’s passing game to produce a touchdown, even if Auburn focuses on limiting the Gators’ rushing attack.
Micah Mays Jr. provides a different route to the end zone as a perimeter receiver in an offense expected to generate multiple scoring opportunities. Florida’s efficiency and Auburn’s defensive profile make Mays an intriguing alternative in this matchup.
- Matchup: Auburn vs Florida
- Date/Time: Saturday, Sept.19 at 7:00 PM E.T
- Location: Jordan O'Hare Stadium, Auburn, Alabama
- TV: ESPN
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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