The No. 13 Vanderbilt Commodores face the Memphis Tigers at the FedEx Center tonight.
Early money has come in on the undefeated Commodores, shifting their line from -7.5 to -9.5, and my Vanderbilt vs Memphis predictions are following that line movement.
Here are my best free college basketball picks for this non-conference clash between in-state foes on Wednesday, December 17.
Vanderbilt vs Memphis prediction
Vanderbilt vs Memphis best bet: Vanderbilt -9.5 (-110)
The Memphis Tigers are coming off a 99-73 loss to Louisville, which snapped a three-game winning streak. They are 4-5 straight up but 7-2 against the spread, with their best win coming against Baylor.
Meanwhile, the Vanderbilt Commodores have gone a perfect 10-0. They have yet to face a ranked team but have blowout wins against VCU, Saint Mary's, and SMU, who are all in the Top 50 at KenPom.
The Commodores are fourth in the country in adjusted offense, rank fourth in 2-point percentage (63.5%), and 47th in 3-point percentage (37.5%) while turning the ball over at the seventh-lowest rate.
Expect them to get buckets against a Memphis side that allows foes to shoot 34.7% from deep and sits outside the Top 300 in threes allowed per game (9.1) and defensive rebounding rate
The Dores haven't been quite as dominant on the other end of the floor, but have still impressed. They are 34th in opponent 2-point percentage (46%) while ranking 29th in defensive rebounding rate.
Dug McDaniel leads Memphis with 14.1 PPG, but he's the only player on the team averaging double-digit points. The Tigers shoot just 48.4% inside the arc and won't have the firepower to keep up with Vandy's up-tempo attack.
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Vanderbilt vs Memphis same-game parlay
Tyler Nickel shoots a sizzling 47.3% from downtown and has knocked down more than 2.5 threes in seven of his last 10 games. He should torch a Memphis team that struggles to defend the arc.
Vandy guard Duke Miles is coming off a game against lowly Central Arkansas, where he had just two assists. He has finished with fewer than 3.5 dimes in all four games against high-major foes.
Vanderbilt vs Memphis SGP
- Vanderbilt -9.5
- Tyler Nickel Over 2.5 threes
- Duke Miles Under 3.5 assists
Our beyond the arc SGP: Can you Dug it?
McDaniel is the only Memphis player capable of creating his own shot, so expect a high shooting volume in a losing cause. He has scored at least 15 points in games against Louisville, Purdue, Wake Forest, and Ole Miss.
Vanderbilt vs Memphis SGP
- Vanderbilt -9.5
- Tyler Nickel Over 2.5 threes
- Duke Miles Under 3.5 assists
- Dug McDaniel Over 13.5 points
Vanderbilt vs Memphis odds
- Spread: Vanderbilt -9.5 | Memphis +9.5
- Moneyline: Vanderbilt -500 | Memphis +375
- Over/Under: Over 158.5 | Under 158.5
Vanderbilt vs Memphis betting trend to know
The Commodores have covered the first half spread in 22 of their last 33 games (+8.95 Units / 23% ROI). Find more college basketball betting trends for Vanderbilt vs. Memphis.
How to watch Vanderbilt vs Memphis
| Location | FedExForum, Memphis, TN |
| Date | Wednesday, December 17, 2025 |
| Tip-off | 7:00 p.m. ET |
| TV | ESPN2 |
Vanderbilt vs Memphis key injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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