The Syracuse Orange will try to build on a two-game winning streak against one of their toughest conference rivals as they visit the Duke Blue Devils tonight.
The Orange are facing an uphill climb, but I still like them to cover the massive spread in my Syracuse vs. Duke predictions.
Let’s see how bettors can approach tonight’s game in my free college basketball picks for Monday, February 16.
Syracuse vs Duke prediction
Syracuse vs Duke best bet: Syracuse +19.5 (-110)
We have two very clear trends heading into tonight’s game. The Syracuse Orange have covered in five straight contests, while the Duke Blue Devils are 0-4 against the spread in their last four games, three of which saw them as a double-digit favorite.
The problem with these huge spreads is that Duke plays slowly, ranking 267th in the country in adjusted tempo. So while the Blue Devils play elite defense, they’ve averaged only 68.8 points per game over their last five. That style makes it hard to win by 20+ points, which is why I’m taking Syracuse to cover.
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Syracuse vs Duke same-game parlay
The Orange aren’t nearly as good as the Blue Devils, but Syracuse will stay in this game in large part because Duke tends to keep the overall scoring down, having hit the Under in six straight. I’m also taking Syracuse guard Nate Kingz to hit at least two shots from deep, something he’s done in five of his last six games.
Syracuse vs Duke SGP
- Syracuse +19.5
- Under 142
- Nate Kingz Over 1.5 made threes
Our beyond the arc SGP: Put up your Dukes
Cameron Boozer (22.8 PPG) is known for his elite scoring, but he does a lot more for the Blue Devils. I’m taking Boozer to hit three other Overs (assists, rebounds, and threes) while helping teammate Isaiah Evans hit his own scoring total of 15.5 points, a number he’s gone Over in each of his last two games.
Syracuse vs Duke SGP
- Isaiah Evans Over 15.5 points
- Cameron Boozer Over 4.5 assists
- Cameron Boozer Over 10.5 rebounds
- Cameron Boozer Over 1.5 made threes
Syracuse vs Duke odds
- Spread: Syracuse +19.5 (-110) | Duke -19.5 (-110)
- Moneyline: Syracuse +1600 | Duke -5000
- Over/Under: Over 142 (-110) | Under 142 (-110)
Syracuse vs Duke betting trend to know
Syracuse is 5-0 ATS in its last five games. Find more college basketball betting trends for Syracuse vs. Duke.
How to watch Syracuse vs Duke
| Location | Cameron Indoor Stadium, Durham, NC |
| Date | Monday, February 16, 2026 |
| Tip-off | 7:00 p.m. ET |
| TV | ESPN |
Syracuse vs Duke key injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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