Purdue vs Indiana Prediction, Picks & Odds for Tonight's College Basketball Game

Ponnaiya's prediction: The Boilermakers are set to roast a shady Hoosiers' defense.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Jan 27, 2026 • 11:20 ET • 4 min read

NCAAB

Match starts: 8 hrs
IND
40 %
PUR
60 %
EXPERT PICK - TOTAL
Purdue o78.5 (-110)
Read Analysis
Braden Smith (3) drives to the basket in the second half against the UCLA Bruins at Pauley Pavilion presented by Wescom Financial.
Photo By - Reuters Connect. Braden Smith (3) drives to the basket in the second half against the UCLA Bruins at Pauley Pavilion presented by Wescom Financial.

The No. 12-ranked Purdue Boilermakers try to snap a two-game skid as they head to Bloomington to face the Indiana Hoosiers tonight.

The Boilermakers have a highly rated offense, and my Purdue vs. Indiana predictions expect them to put up points at Assembly Hall. 

Here are my free college basketball picks for this rivalry clash on January 27

Purdue vs Indiana prediction

Purdue vs Indiana best bet: Purdue team total Over 78.5 (-120)

The Purdue Boilermakers are fresh off an 88-82 loss to No. 9 Illinois. They had a sizzling 62.9 eFG% and turned the ball over just three times against the Illini, but couldn't overcome a 46-point game from Keaton Wagler.

They should bounce back against the Indiana Hoosiers, who are 1-4 in their last five and have struggled defensively. The Hoosiers have allowed fewer than 80 points in just three of their last seven games, with two of those coming against Rutgers and Maryland, who sit outside the Top 140 in adjusted offense.

IU won't be able to contain a highly-efficient Purdue attack that is second in the country in adjusted offense and ranks eighth in eFG% (58.6%). 

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Purdue vs Indiana same-game parlay

Point guard Braden Smith is the focal point of Purdue's highly-rated offense. Smith leads the country with 9.3 assists per game and has dropped at least eight assists in 15 of 20 games

Trey Kaufman-Renn has struggled the last few weeks, but the senior forward averaged 20.1 points per game on 59.7 2PT% last year. He should get back on track against an Indiana side that sits 15th in conference play in opponent 2PT% (56%).

Purdue vs Indiana SGP

  • Purdue team total Over 78.5
  • Braden Smith Over 7.5 assists
  • Trey Kaufman-Renn Over 12.5 points

Our beyond the arc SGP: Lamr LeMerrier

Purdue also has defensive issues, especially against teams with shot-makers who can punish them on switches. That makes this a good spot for Indiana's Lamar Wilkerson (19.4 ppg, 3.2 rpg), who has scored 19+ points and grabbed at least four boards in seven of his last nine games.

Purdue vs Indiana SGP

  • Purdue team total Over 78.5
  • Braden Smith Over 7.5 assists
  • Trey Kaufman-Renn Over 12.5 points
  • Lamar Wilkerson Over 18.5 points
  • Lamar Wilkerson Over 3.5 rebounds

Purdue vs Indiana odds

  • Spread: Purdue -5 | Indiana +5
  • Moneyline: Purdue -220 | Indiana +180
  • Over/Under: Over 151.5 | Under 151.5

Purdue vs Indiana betting trend to know

The Boilermakers have covered the first-half spread in 21 of their last 35 games (+4.60 Units / 11% ROI). Find more college basketball betting trends for Purdue vs. Indiana.

How to watch Purdue vs Indiana

Location Simon Skjodt Assembly Hall, Bloomington, IN
Date Tuesday, January 27, 2026
Tip-off 9:00 p.m. ET
TV Peacock

Purdue vs Indiana key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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