Penn State vs Ohio State Prediction, Picks & Odds for Tonight's College Basketball Game

Ohio State isn’t a total powerhouse, but the Buckeyes have more than enough in the tank to cover this double-digit spread.

Ed Scimia - Contributor at Covers.com
Ed Scimia • Betting Analyst
Jan 26, 2026 • 13:19 ET • 4 min read

NCAAB

Match starts: 4 hrs
OSU
50 %
PSU
50 %
EXPERT PICK - SPREAD
Ohio St. -11.5 (-110) Ohio St. -11.5 (-110)
Read Analysis
John Mobley Jr. (0) celebrates after the game against the Minnesota Golden Gophers at Value City Arena.
Photo By - Reuters Connect. John Mobley Jr. (0) celebrates after the game against the Minnesota Golden Gophers at Value City Arena.

The Penn State Nittany Lions will try to end a six-game losing streak when they visit the Ohio State Buckeyes tonight.

The Nittany Lions may be getting a boatload of points tonight, but it’s not enough for me to bet against the Buckeyes in my Penn State vs. Ohio State predictions.

Read on to see my full thoughts on tonight’s matchup in my free college basketball picks for Monday, January 26.

Penn State vs Ohio State prediction

Penn State vs Ohio State best bet: Ohio State -11.5 (-110)

Penn State is still searching for its first Big Ten win after eight consecutive conference losses, and it’s far from clear when that victory might come.

There have been some close calls along the way, but this team is fundamentally lacking in talent on both sides of the ball compared to the rest of the conference.

Even as the Nittany Lions played three schools they should be competitive against in their last three games, they lost each by double digits.

While Penn State lacks imposing scoring threats — Kayden Mingo leads the way at 14.6 ppg — their real issues come on the defensive end.

The Nittany Lions allow opponents to shoot 48.5% from the floor and 37.8% from 3-point range, both among the very worst numbers in the country. Even accounting for the strength of schedule, KenPom rates this defense outside the Top 200.

Ohio State isn’t elite, but the Buckeyes are a tournament-level team that is far better across the board. At home, even this spread seems far too small given the gap between these two programs right now.

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Penn State vs Ohio State same-game parlay

While I expect Ohio State to win this game with ease, this shouldn’t be a shootout. These teams both play at relatively slow paces and neither has a clear trend to either side of the total, so I’m taking the Under tonight.

John Mobley has hit at least four 3-pointers in each of his last three games and six of his last eight outings overall.

Penn State vs Ohio State SGP

  • Ohio State -11.5
  • Under 153
  • John Mobley Over 3.5 threes

Penn State vs Ohio State odds

  • Spread: Penn State +11.5 | Ohio State -11.5
  • Moneyline: Penn State +550 | Ohio State -800
  • Over/Under: Over 153 | Under 153

Penn State vs Ohio State betting trend to know

Ohio State is 4-1 ATS in its last five games overall. Find more college basketball betting trends for Penn State vs. Ohio State.

How to watch Penn State vs Ohio State

Location Value City Arena, Columbus, OH
Date Monday, January 26, 2026
Tip-off 7:00 p.m. ET
TV FS1

Penn State vs Ohio State key injuries

Odds are correct at the time of publishing and are subject to change.
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Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

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