Yankees vs Red Sox Prediction, Picks & Odds for Today's MLB Game

Chris Hatfield - Contributor at Covers.com
Chris Hatfield • Betting Analyst 12+ years betting experience
Updated: Apr 23, 2026 , 10:26 AM ET • 4 min read

Hatfield's prediction: Bombers sweep Red Sox behind another Schlittler gem.

MLB

Match starts: 6 hrs
NYY
63 %
BOS
37 %
EXPERT PICK - MONEYLINE
NY Yankees -143 NY Yankees -143
Read Analysis
Cam Schlittler New York Yankees MLB
Photo By - Reuters Connect. Cam Schlittler in MLB action.

The New York Yankees will try to complete a road sweep of the Boston Red Sox tonight behind the electric Cam Schlittler.

My Yankees vs. Red Sox predictions believe Boston righty Payton Tolle is completely outmatched, and my MLB picks will take the Bombers moneyline on Thursday, April 23. 

Who will win Yankees vs Red Sox today: Yankees moneyline (-143)

I’ve tried to find a scenario where the Boston Red Sox should be less than a +150 underdog to avoid the sweep against New York Yankees righty Cam Schlittler, and I just can’t get there. I’d play this to around -160.

Schlittler threw eight scoreless innings and registered 12 strikeouts against his boyhood team in last year's postseason.

Schlittler's most thrown pitch, the fastball, has been one of the best pitches in baseball, ranking in the 100th percentile of run value.

Boston righty Payton Tolle, meanwhile, is walking over 10% of batters he faces and is carrying a 4.70 xERA.

New York shouldn’t need to score much to get the win.

Covers COVERS INTEL: Schlittler’s chase rate sits at 41% through five starts, ranking him in the Top 2% of the sport.

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Yankees vs Red Sox Over/Under pick: Under 8.5 (-120)

I’m not sure this one looks much different from yesterday when Max Fried threw eight scoreless innings in a near-shutout win. I’ll back the Under here with a projected total of 8.1. 

This Under lives and dies with Schlittler, and I'm fine with that. He’ll get plenty of chase, as Boston’s Top 7 whiff rate and Bottom 7 chase contact rate looms large..

Tolle's command issues could let the Yankees get to four or five runs, but this still doesn't feel like an eight-run ballgame.

Chris Hatfield's 2026 Transparency Record
  • ML/RL bets: 7-6, +0.92 units
  • Over/Under bets: 8-6, +2 units

Yankees vs Red Sox odds

  • Moneyline: Yankees -150 | Red Sox +130
  • Run line: Yankees -1.5 | Red Sox +1.5
  • Over/Under: Over 8.5 | Under 8.5

Yankees vs Red Sox trend

The Red Sox have hit the Under in 24 of their last 40 games at home (+7.35 Units / 17% ROI). Find more MLB betting trends for Yankees vs. Red Sox.

How to watch Yankees vs Red Sox and game info

Location Fenway Park, Boston, MA
Date Thursday, April 23, 2026
First pitch 6:10 p.m. ET
TV FS1
Yankees starting pitcher Cam Schlittler
(2-1, 1.95 ERA)
Red Sox starting pitcher Payton Tolle
(0-1, 6.06 ERA)

Yankees vs Red Sox latest injuries

Yankees vs Red Sox weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Chris Hatfield - Covers.com
Betting Analyst

Chris has always had a passion for three things: solving problems, sports, and writing. It’s no wonder then that he found himself attracted to the sports betting industry. You can find Chris betting every day. Whether it’s shot prop markets in Champions League Soccer qualifiers or NBA Summer League, he has no offseason. As an EV+ bettor, he especially values the insight gained through a data-driven approach.

His work has been featured on various websites such as SBNation, Rivals, Bleacher Report, and 247Sports. He has appeared on radio outlets such as ESPN 680 and The Sharp 600 podcast. You can listen to his own podcast, “What High School Did You Go To?” on Apple Podcast and Soundcloud.

Chris has carved out a niche as a college basketball originator with massive profitability success in that sport and stresses one piece of advice to sports bettors: exploit edges as broadly as possible and take advantage of them while they last. His preferred sportsbook is bet365 because of the range of markets you can find.

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