The Minnesota Twins have a prime opportunity to complete the sweep on Wednesday afternoon with Erick Fedde taking the mound for the Chicago White Sox.
My Twins vs. White Sox predictions will explain why I expect Minnesota to finish the job at home.
Read more in my MLB picks for Wednesday, June 3.
Who will win White Sox vs Twins today: Twins moneyline (-150)
The Minnesota Twins offense gets a favorable matchup against Chicago White Sox starter Erick Fedde in Wednesday's series finale. The veteran right-hander has struggled recently, posting a 7.04 FIP across his last two starts. His road numbers are concerning as well, as he owns a 5.30 xFIP away from home this season.
Minnesota's power profile is particularly appealing in this matchup. The Twins rank 14th in home runs, while Fedde has allowed nearly 50% of his contact to come in the air on the road. Even more concerning, 17.6% of those fly balls have left the yard. Fedde has also surrendered 10 earned runs over his last two outings.
Taj Bradley's recent 5.00 ERA doesn't tell the full story. The right-hander owns a 3.14 xERA across his last two starts and has allowed just a 5% barrel rate during that span.
I'll play this pick up to -160.
COVERS INTEL: Fedde has allowed a 44.8% hard-hit rate over his last two outings. 
White Sox vs Twins Over/Under pick: Under 8.5 (+100)
This game could ultimately come down to how much offense Minnesota generates against Fedde because Chicago's bullpen has been lights out lately. Over the last week, the White Sox relievers own a 2.95 FIP and have held opponents to a minuscule 2.8% barrel rate.
The Twins' bullpen, meanwhile, owns a 5.05 xERA over the last seven days. However, Bradley has consistently worked deep into games, limiting Minnesota's reliance on its relievers. That should help against a White Sox lineup that has struggled to generate quality contact recently, posting just a 7.8% barrel rate over the last week.
I'll play this pick up to -110.
- ML/RL bets: 21-14, +5.92 units
- Over/Under bets: 20-14, +2.40 units
White Sox vs Twins odds
- Moneyline: White Sox +138 | Twins -144
- Run line: White Sox +1.5 (-156) | Twins -1.5 (+144)
- Over/Under: Over 8.5 (-113) | Under 8.5 (+108)
White Sox vs Twins trend
Minnesota has won two straight as moneyline favorites against Chicago. Find more MLB betting trends for White Sox vs. Twins.
How to watch White Sox vs Twins and game info
| Location | Target Field, Minneapolis, MN |
| Date | Wednesday, June 3, 2026 |
| First pitch | 1:40 p.m. ET |
| TV | CHSN, Twins.TV |
| White Sox starting pitcher | Eric Fedde (0-5, 5.40 ERA) |
| Twins starting pitcher | Taj Bradley (5-1, 3.21 ERA) |
White Sox vs Twins latest injuries
White Sox vs Twins weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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