This game is priced as a coin flip, with Chicago and Texas both carrying -110 odds on the moneyline.
Anthony Kay is not pitching as well as his results indicate, and the lefty-mashing Rangers should take full advantage of that.
Let's break it all down with my White Sox vs. Rangers predictions and MLB picks for Wednesday, July 22.
Who will win White Sox vs Rangers today: Texas Rangers moneyline (-110)
Anthony Kay’s 3.15 ERA has masked the fact he owns a 4.85 xFIP over the last 30 days.
The southpaw is playing with fire, and there’s real potential he gets burned against the Texas Rangers.
They have hammered left-handed pitching unlike any other team, ranking first in average, OPS, and wOBA since June 1.
The Chicago White Sox sit 21st in wOBA vs. right-handed pitching this month. They’re in a bit of a rut, which should help Cal Quantrill avoid a blow up.
Back the Rangers to take the rubber match up to -125.
COVERS INTEL: Kay ranks in the 12th percentile with a 5.35 xERA this season.
White Sox vs Rangers Over/Under pick: Over 8.5 (-120)
Kay has posted an xERA of 5.05 or worse in three of his last four starts. He’s allowing a lot of quality contact and it’ll be tough to get the cat back in the bag against an offense feasting on lefties.
While the White Sox haven’t lit it up of late, this is a good spot to get on track. They’ll see a lot of Quantrill, who ranks in the 21st percentile in barrel rate and has allowed 2.14 homers per nine innings the last month. That should play well for their power.
Bet to -130.
- ML/RL bets: 62-50, +1.15 units
- Over/Under bets: 62-45-5, +9.34 units
White Sox vs Rangers weather
This game will be played in a dome.
White Sox vs Rangers odds
- Moneyline: Chicago -110 | Texas -110
- Run line: Chicago -1.5 (+150) | Texas +1.5 (-175)
- Over/Under: Over 8.5 (-120) | Under 8.5 (+100)
White Sox vs Rangers trend
Texas has hit the Game Total Over in 18 of the last 24 home games (+11.35 units, 42% ROI). Find more MLB betting trends for White Sox vs. Rangers.
How to watch White Sox vs Rangers and game info
| Location | Globe Life Field, Arlington, TX |
| Date | Wednesday, July 22, 2026 |
| First pitch | 8:05 p.m. ET |
| TV | CHSN, RSN |
| White Sox starting pitcher | Anthony Kay (6-4, 4.24 ERA) |
| Rangers starting pitcher | Cal Quantrill (3-2, 3.93 ERA) |
White Sox vs Rangers latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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