The Cleveland Guardians will be searching for their fifth straight victory tonight as they take on the Detroit Tigers. First pitch is scheduled for 6:40 p.m. ET at Comerica Park.
While Tanner Bibee has had bad luck this season, I’m eyeing Cleveland to deliver another high-scoring win in my Guardians vs. Tigers predictions.
Read more in my MLB picks for Wednesday, May 20.
Who will win Guardians vs Tigers today: Guardians moneyline (-117)
The Cleveland Guardians are 7-3 in their last 10 games, notching four consecutive victories on the road.
Tanner Bibee owns an 0-6 record, but his 4.15 ERA is respectable, and the right-hander has improved lately. He’s only surrendered four earned runs across his last two starts, lasting at least six frames in each.
The Guardians are currently flourishing offensively. The Detroit Tigers haven’t announced who will pitch here, but it’ll likely be an opener.
Regardless of who’s on the bump, Cleveland should continue to produce. They’ve scored 29 runs across the last four games.
COVERS INTEL: The Guardians are sixth in wRC+ (107) over the last two weeks. 
Guardians vs Tigers Over/Under pick: Over 7.5 (-112)
Although Bibee has been better over the last few weeks, he’s still struggled on the road, and the Tigers are scoring more runs at home overall, averaging 4.13 per contest.
Bibee won’t get lit up, but he’s also not going to throw a scoreless gem, either.
As for Detroit’s pen, they own an ERA just under 4.00. The Guardians are averaging 7.33 runs per game across their last three, making the most of their offensive opportunities.
With a total this low, there’s clear value in the Over.
- ML/RL bets: 12-11, +2.26 units
- Over/Under bets: 14-9, +3.16 units
Guardians vs Tigers odds
- Moneyline: Guardians -117 | Tigers +113
- Run line: Guardians -1.5 (+144) | Tigers +1.5 (-150)
- Over/Under: Over 7.5 (-108) | Under 7.5 (+104)
Guardians vs Tigers trend
The Guardians have hit the Moneyline in 22 of their last 35 away games (+13.95 Units / 37% ROI). Find more MLB betting trends for Guardians vs. Tigers.
How to watch Guardians vs Tigers and game info
| Location | Comerica Park, Detroit, MI |
| Date | Wednesday, May 20, 2026 |
| First pitch | 6:40 p.m. ET |
| TV | Guardians.TV, DSN |
| Guardians starting pitcher | Tanner Bibee (0-6, 4.15 ERA) |
| Tigers starting pitcher | TBD |
Guardians vs Tigers latest injuries
Guardians vs Tigers weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
