The Chicago Cubs and Milwaukee Brewers will meet for the second of a three-game set this evening.
The Brewers took the first game last night in comfortable fashion and, with their ace on the mound tonight, look poised to make it two straight.
Read all about it in my Brewers vs. Cubs predictions and MLB picks for Tuesday, May 19.
Who will win Brewers vs Cubs today: Brewers moneyline (-115)
If you haven't heard, this Jacob Misiorowski guy is pretty good. His May has been spotless, allowing zero runs over three starts, and his 99th percentile K rate and whiff rate should have some success here.
Collectively, the Chicago Cubs don't strikeout a ton, but you can quiet the big bats like Ian Happ, Pete Crow-Armstrong, and Seiya Suzuki, who all have over a 25% K rate.
On the other side, the Milwaukee Brewers' 23% whiff rate and 26% chase rate are a problem for Ben Brown, who needs hitters to expand the zone to play. I'd play this to -130.

Brewers vs Cubs Over/Under pick: Under 7.5 (+100)
Two starters with sub-2.50 expected ERAs walk into two lineups that have different matchup issues.
The Brewers' offense should score because of its patient approach, but it can still struggle from time to time because it relies on stringing hits together. Brown, who is likely a quasi-opener, going three to four innings, should have some success against that with a rested bullpen behind.
Meanwhile, Misiorowski should do Miz things with a 92nd percentile barrel suppression rate among other elite metrics. I projected exactly 7 runs.
- ML/RL bets: 18-18, -0.84 units
- Over/Under bets: 22-14, +10.54 units
Brewers vs Cubs odds
- Moneyline: Milwaukee -115 | Chicago -105
- Run line: Milwaukee -1.5 | Chicago +1.5
- Over/Under: Over 8 | Under 8
Brewers vs Cubs trend
The Milwaukee Brewers have covered the Run Line in 27 of their last 45 games (+13.60 Units / 26% ROI). Find more MLB betting trends for Brewers vs. Cubs.
How to watch Brewers vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Tuesday, May 19, 2026 |
| First pitch | 7:40 p.m. ET |
| TV | Brewers.TV, MARQ |
| Brewers starting pitcher | Jacob Misiorowski (3-2, 2.12 ERA) |
| Cubs starting pitcher | Ben Brown (1-1, 1.60 ERA) |
Brewers vs Cubs latest injuries
Brewers vs Cubs weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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