The Milwaukee Brewers and Chicago Cubs open a series Monday night at Wrigley Field in the first meeting between these NL Central rivals since the Brewers won Game 5 of last October's NLDS. We like the Cubs to get revenge.
Read all about it in my Brewers vs. Cubs predictions and MLB picks for Monday, May 18, 2026.
Who will win Brewers vs Cubs today: Cubs -1.5 (+110)
Brandon Sproat takes the mound for the Milwaukee Brewers tonight with a concerning profile, especially against a team like the Chicago Cubs.
His pitching run value ranks in the third percentile of baseball, with the breaking ball slightly worse than that. That’s a problem against the Cubs because it forces him to rely too much on the fastball, which is a pitch the Cubs hit as well as any team in the sport.
On the other side is Shota Imanaga. His diverse skill set, which has resulted in a chase rate in the 99th percentile, will neutralize the Brewers' bats tonight. I would play this down to -110.

Brewers vs Cubs Over/Under pick: Under 10.5 (-105)
A very windy Wrigley Field has pushed this total up at least a full run. I get it. I still think it's a bit too much.
Imanaga has been sensational over the past month, and his 91st percentile whiff rate should grab some easy outs.
The Brewers are a disciplined lineup that chases at right around 25%, but that doesn't matter much here. Imanga generates swing-and-miss with pure stuff, which poses unique issues.
On the other hand, while I expect the Cubs to score enough to cover, it won't be enough to push this Over. I'd play to 10.
- ML/RL bets: 18-17, +.16 units
- Over/Under bets: 22-13, +11.59 units
Brewers vs Cubs odds
- Moneyline: Brewers +139 | Cubs -168
- Run line: Brewers +1.5 (-136) | Cubs -1.5 (+113)
- Over/Under: Over 10.5 (-112) | Under 10.5 (-107)
Brewers vs Cubs trend
The Chicago Cubs have hit the Moneyline in their last 15 games at home (+15.00 Units / 66% ROI)Find more MLB betting trends for Brewers vs. Cubs.
How to watch Brewers vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Monday, May 18, 2026 |
| First pitch | 7:40 p.m. ET |
| TV | Brewers.TV, Marquee |
| Brewers starting pitcher | Brandon Sproat (1-2, 5.75 ERA) |
| Cubs starting pitcher | Shota Imanaga (4-3, 2.32 ERA) |
Brewers vs Cubs latest injuries
Brewers vs Cubs weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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