The Los Angeles Angels hope to avoid a sweep as they host the Athletics tonight in Anaheim.
My A’s vs. Angels predictions see the Halos grabbing a much-needed win with ace Jose Soriano on the bump.
Who will win A's vs Angels today: Angels moneyline (-108)
Jose Soriano has been flat-out one of the most effective starting pitchers in baseball, taking the leap from solid rotation piece to bona fide ace.
The right-hander has a 2.41 ERA through 10 starts primarily thanks to his elite swing-and-miss stuff. He rides a 93rd percentile whiff rate en route to a 28% strikeout rate.
When he’s not striking batters out, he’s doing the next-best thing — inducing soft-contact (75th percentile in hard-hit rate) grounders (81st percentile in ground ball rate).
The Los Angeles Angels are a different team with their flamethrower on the hill, winning 70% of his starts.
COVERS INTEL: The A’s hit the ball to the opposite field more than any other team (31.7% in May). That’s not typically a viable approach against Soriano, who has the seventh-lowest Oppo% (16.6%) among qualified starters.
A's vs Angels Over/Under pick: Under 8.5 (-115)
One thing about betting on the Angels is that it’s difficult to count on much run support from the lineup, which has a league-worst 54 wRC+ against RHP this month.
Luis Severino allows too many baserunners (1.57 WHIP) for me to rely on him to lead his team to victory, but he could help keep this a low-scoring game against the Angels.
His 107 Stuff+ ranks 12th among qualified starters, and this is the second consecutive season in which he’s been more effective on the road (3.56 ERA).
- ML/RL bets: 14-15 -5.53 units
- Over/Under bets: 22-8, +13.64 units
A's vs Angels odds
- Moneyline: A's -110 | Angels -110
- Run line: A's -1.5 (+135) | Angels +1.5 (-180)
- Over/Under: Over 8.5 (-115) | Under 8.5 (-110)
A's vs Angels trend
The A’s are 6-16-1 O/U in their last 23 road games. Find more MLB betting trends for A's vs. Angels.
How to watch A's vs Angels and game info
| Location | Angels Stadium, Anaheim, CA |
| Date | Thursday, May 21, 2026 |
| First pitch | 9:38 p.m. ET |
| TV | NBCS-California, ABTV |
| A's starting pitcher | Luis Severino (2-5, 4.45 ERA) |
| Angels starting pitcher | Jose Soriano (6-3, 2.41 ERA) |
A's vs Angels latest injuries
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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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