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MLB Picks

Get free expert and computer MLB picks for every game on Sept. 26, 2026.

New Computer Picks powered by Odds Shark

Predicted Score

HOU logo
HOU
HOU

6.50 @ 4.81

ATH
ATH logo
ATH

Astros vs Athletics · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

HOU logo
HOU
HOU

6.50

-177

o9.0 -105

-1.5 -110

ATH logo
ATH
ATH

4.81

+162

u9.5 -128

+1.5 -102

Arizona @ San Diego
Matchup Stats

Predicted Score

AZ logo
AZ
AZ

4.20 @ 4.04

SD
SD logo
SD

Diamondbacks vs Padres · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

AZ logo
AZ
AZ

4.20

+117

o7.5 -109

+1.5 -175

SD logo
SD
SD

4.04

-126

u7.5 -104

-1.5 +168

Top Projection Gabriel Moreno o0.5 Total RBIs (+236)
o0.5+245
LA Angels @ Seattle
Matchup Stats

Predicted Score

LAA logo
LAA
LAA

3.59 @ 3.60

SEA
SEA logo
SEA

Angels vs Mariners · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAA logo
LAA
LAA

3.59

+102

o6.5 -112

+1.5 -200

SEA logo
SEA
SEA

3.60

-115

u6.5 -102

-1.5 +163

Top Projection Josh Lowe o0.5 Total RBIs (+350)
o0.5+350
LA Dodgers @ San Francisco
Matchup Stats

Predicted Score

LAD logo
LAD
LAD

5.77 @ 2.57

SF
SF logo
SF

Dodgers vs Giants · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAD logo
LAD
LAD

5.77

-295

o7.5 -114

-2.5 -108

SF logo
SF
SF

2.57

+275

u8.0 -120

+2.5 -102

Top Projection Teoscar Hernandez o0.5 Total RBIs (+195)
o0.5+195
Pittsburgh @ Detroit
Matchup Stats

Predicted Score

PIT logo
PIT
PIT

4.36 @ 4.39

DET
DET logo
DET

Pirates vs Tigers · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

PIT logo
PIT
PIT

4.36

--

--

--

DET logo
DET
DET

4.39

--

--

--

Cincinnati @ Toronto
Matchup Stats

Predicted Score

CIN logo
CIN
CIN

4.26 @ 4.53

TOR
TOR logo
TOR

Reds vs Blue Jays · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CIN logo
CIN
CIN

4.26

+135

o7.5 -122

+1.5 -160

TOR logo
TOR
TOR

4.53

-155

u8.5 -132

-1.5 +141

LA Dodgers @ San Francisco
Matchup Stats

Predicted Score

LAD logo
LAD
LAD

5.56 @ 2.65

SF
SF logo
SF

Dodgers vs Giants · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAD logo
LAD
LAD

5.56

-325

o7.0 -125

-1.5 -181

SF logo
SF
SF

2.65

+280

u7.5 -119

+1.5 +149

NY Mets @ Washington
Matchup Stats

Predicted Score

NYM logo
NYM
NYM

5.10 @ 4.65

WAS
WAS logo
WAS

Mets vs Nationals · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

NYM logo
NYM
NYM

5.10

-130

o8.0 -125

-1.5 +130

WAS logo
WAS
WAS

4.65

+115

u8.5 -114

+1.5 -143

Atlanta @ Miami
Matchup Stats

Predicted Score

ATL logo
ATL
ATL

5.07 @ 4.44

MIA
MIA logo
MIA

Braves vs Marlins · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

ATL logo
ATL
ATL

5.07

--

--

--

MIA logo
MIA
MIA

4.44

--

--

--

Texas @ Minnesota
Matchup Stats

Predicted Score

TEX logo
TEX
TEX

4.79 @ 4.06

MIN
MIN logo
MIN

Rangers vs Twins · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TEX logo
TEX
TEX

4.79

--

--

--

MIN logo
MIN
MIN

4.06

--

--

--

Cleveland @ Kansas City
Matchup Stats

Predicted Score

CLE logo
CLE
CLE

4.55 @ 4.60

KC
KC logo
KC

Guardians vs Royals · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CLE logo
CLE
CLE

4.55

+100

o8.0 -115

-1.5 +163

KC logo
KC
KC

4.60

+110

u8.5 -118

+1.5 -159

Colorado @ Chi. White Sox
Matchup Stats

Predicted Score

COL logo
COL
COL

4.06 @ 4.85

CHW
CHW logo
CHW

Rockies vs White Sox · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

COL logo
COL
COL

4.06

+195

o7.5 -132

+1.5 -112

CHW logo
CHW
CHW

4.85

-230

u8.5 -130

-1.5 +100

St. Louis @ Milwaukee
Matchup Stats

Predicted Score

STL logo
STL
STL

3.88 @ 4.31

MIL
MIL logo
MIL

Cardinals vs Brewers · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

STL logo
STL
STL

3.88

+160

o7.5 -110

+1.5 -140

MIL logo
MIL
MIL

4.31

-188

u7.5 +100

-1.5 +122

Houston Astros image thumbnail HOU @ Athletics Athletics image thumbnail ATH Fri, Sep 25 • 9:40 PM ET
Total Home Runs
Yordan Alvarez logo Yordan Alvarez o0.5 Total Home Runs (+271)
Best Odds
Pick made: 8 hours ago
Josh Inglis logo
Josh Inglis
Betting Analyst

It must be the end of the season because we're getting Yordan Alvarez at one of his best prices in weeks, in maybe the best home-run matchup on the entire slate. Alvarez should be priced at 3.2x, not 3.7x, today against Jacob Lopez in Sacramento. Lopez looks like he wants to call it a season after giving up 10 runs in his last start and 19 runs over his last three starts, spanning just 12.1 innings. Lopez has also allowed multiple homers in three of his last four games, and Alvarez has taken him deep once in five meetings. This is the best September hitting weather, with winds blowing out, a tired starter who looks ready to wrap it up, and the price is right. Full send here.

Total Home Runs
Zack Gelof logo Zack Gelof o0.5 Total Home Runs (+710)
Best Odds
Pick made: 9 hours ago
Josh Inglis logo
Josh Inglis
Betting Analyst

This was a run-not-walk trade at a fair price of 6x, not 8.1x. Zack Gelof just launched two homers last night in Sacramento and has five dingers over his last 10 games. He has 22 on the season and gets the best hitting conditions on the board today at Sutter Health Park, with winds blowing out and decent temperatures. Hunter Brown is on the other side, which is a big reason why this is priced this long, but Gelof has a .936 OPS at home compared to .664 on the road and has seen Brown 14 times. The numbers aren't great, but there is some familiarity there. Sutter Health Park can get to even the best pitchers, which is why it finished as the best Over park of the season at better than 60%.

View 15 Picks
Arizona Diamondbacks image thumbnail AZ @ San Diego Padres image thumbnail SD Fri, Sep 25 • 9:40 PM ET
Total Home Runs
Corbin Carroll logo Corbin Carroll o0.5 Total Home Runs (+400)
Best Odds
Pick made: 10 hours ago
Todd Cordell logo
Todd Cordell
Betting Analyst

Corbin Carroll hasn’t hit for average, but he’s generated barrels at a remarkably high 20.2% clip against fastballs, splitters, and sliders over the last 25 games. That has led to an ISO of nearly .240.

It’s also worth noting Carroll’s had Casey Mize’s number, albeit over a limited sample. He is 4-6 with four hard hit balls and a triple against Mize.

Total
Arizona Diamondbacks image thumbnail San Diego Padres image thumbnail o7.5 (-105)
Best Odds
Pick made: 10 hours ago
Todd Cordell logo
Todd Cordell
Betting Analyst

A 7.5 total is a touch low, and I’m jumping on the Over to 54%.

Case Mize has allowed 3.3 runs per start with the San Diego Padres despite failing to complete five innings on average. 

Brandon Pfaadt has not been sharp (4.63 ERA, 4.23 xERA) over the last month. That should be exposed by a Padres offense sitting Top-5 in wOBA and SLG against righties in September.

View 14 Picks
Los Angeles Angels image thumbnail LAA @ Seattle Mariners image thumbnail SEA Fri, Sep 25 • 10:10 PM ET
Strikeouts Thrown
Reid Detmers logo Reid Detmers o6.5 Strikeouts Thrown (-139)
Best Odds
Pick made: 11 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Detmers has been generating plenty of swings and misses lately, posting 9.60 K/9 over his last five appearances and clearing this number in three of his previous four. He also punched out eight Mariners just 10 days ago, and Seattle has averaged 8.71 strikeouts per game at home this season. Another strong strikeout performance is well within reach.

Strikeouts Thrown
Reid Detmers logo
Reid Detmers u6.5 Strikeouts Thrown (-105)
Projection 6.04
Best Odds
Pick made: 4 minutes ago
EV Model Rating
Star rating: 3 out of 5
It is anticipated that we will see a Hitters Umpire (Andy Fletcher) calling pitches today.. Projected catcher Travis d'Arnaud profiles as a weak pitch framer, per the leading projection system (THE BAT).. The wind projects to be blowing out to LF at 15-mph in this contest, the most-favorable of the day for hitters.. With 6 batters of opposing handedness in the opposing team's projected lineup, Reid Detmers meets a tough challenge while lacking the platoon advantage in most plate appearances in this game.. Reid Detmers will be at a disadvantage playing on the road in today's matchup.
View 11 Picks
Los Angeles Dodgers image thumbnail LAD @ San Francisco Giants image thumbnail SF Fri, Sep 25 • 10:15 PM ET
Total Bases
Mookie Betts logo Mookie Betts o1.5 Total Bases (+103)
Best Odds
Pick made: 11 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Betts is seeing the ball exceptionally well, batting .458 over the last week with seven of his 11 hits going for extra bases. He's topped 1.5 total bases in five of his last seven games and now draws struggling rookie Yunior Marte along with a Giants bullpen carrying a 6.78 FIP over its last 22 innings. Betts should have plenty of opportunities to stay hot.

Total Home Runs
Max Muncy logo Max Muncy o0.5 Total Home Runs (+434)
Best Odds
Pick made: 11 hours ago
Ethan Diamandas logo
Ethan Diamandas
Betting Analyst

Play Max Muncy to 23% for a quarter unit. Muncy has 22 homers against right-handed pitching and matches up well with Marte’s four-seam-heavy arsenal.

View 14 Picks
Pittsburgh Pirates image thumbnail PIT @ Detroit Tigers image thumbnail DET Sat, Sep 26 • 1:10 PM ET
Moneyline
Detroit Tigers image thumbnail DET (-120)
Phil Naessens logo
Phil Naessens
Betting Analyst

Detroit sits at the top of baseball over the last 14 days with a 137 wRC+, pairing a .380 on-base percentage with a 3.53 bullpen SIERA. Justin Verlander takes the mound at Comerica Park for the final start of his Hall of Fame career. Facing a Pittsburgh bullpen carrying a 1.34 WHIP and 4.61 ERA, the Tigers hold massive offensive and bullpen advantages in an emotional home spot.

View Pick
Cleveland Guardians image thumbnail CLE @ Kansas City Royals image thumbnail KC Sat, Sep 26 • 7:10 PM ET
Moneyline
Cleveland Guardians image thumbnail CLE (-129)
Best Odds
Pick made: 3 hours ago
Phil Naessens logo
Phil Naessens
Betting Analyst

Cleveland enters the weekend in an all-out battle for the AL Central crown and the crucial first-round bye (No. 2 seed). Tanner Bibee gets the start, backed by a bullpen that ranks third in MLB over the last two weeks with a 2.99 SIERA and 31.3% strikeout rate. Kansas City's bullpen has faltered down the stretch (5.08 ERA, 1.47 WHIP), giving Cleveland a major late-inning edge with season-defining motivation.

View Pick
Arizona Diamondbacks image thumbnail AZ @ San Diego Padres image thumbnail SD Sat, Sep 26 • 8:40 PM ET
Moneyline
Arizona Diamondbacks image thumbnail AZ (+106)
Best Odds
Pick made: 3 hours ago
Phil Naessens logo
Phil Naessens
Betting Analyst

Arizona has rattled off five straight wins to stay alive in the wild-card race and gives the ball to Corbin Burnes in a must-win game. San Diego has already punched their postseason ticket, while the Diamondbacks offense has caught fire over the last fortnight (128 wRC+, .500 SLG, 3.49 bullpen SIERA). Getting Burnes backed by high urgency against Walker Buehler provides the premier late-game value on the board.

View Pick

What Is An MLB Computer Pick?

MLB picks are bet suggestions based on our computer's assessment of the game. Tons of betting data goes into a computer pick, including pitching matchups, injury reports, analytics, and even recent betting trends.

How To Use MLB Computer Picks

You can use the tables above to help with your bets during the MLB season. The first section includes free, computer-generated picks for daily Major League Baseball games. Baseball bettors can choose to follow the computer, fade the computer, or simply use our computer picks as one element of their betting strategy.

This page also tees up access to deeper betting trends. For example, if a club's run line is favored, you can check their ATS trends, potentially opening up some quality underdog bets.

If you're ready to get started with MLB betting, visit our dedicated page highlighting the best MLB betting sites.

Moneyline

This is the most common and easiest wager for a bettor to make when it comes to MLB picks. Basically, to win an MLB moneyline pick, you just have to choose which team will win the game.

It's simple: if you bet the White Sox moneyline over the Red Sox and Chicago wins, you win your bet.

Run line

The run line is another name for a point spread that you may be more familiar with in NBA and NFL betting. A point spread varies in the NFL and NBA from as little as 0.5 points up to double-digit spreads. A baseball run line is almost always a 1.5-point spread.

The favorite will be -1.5 while the underdog will be +1.5. At the end of the game, if you take away 1.5 runs from the favorite or add 1.5 runs to the underdog and they end up winning the game, you win your MLB pick against the spread.

Totals (Over/Under)

Another common wager is to bet on the total in baseball, which is a bet on the total runs scored in the baseball game. You are simply choosing whether the final score will be Over or Under that total. Betting the Over/Under on a matchup is a great way to get started in MLB score predictions.

Free Computer Picks by Odds Shark

More MLB Picks & Betting Tools

NRFI/YRFI MLB Picks

A new and emerging MLB betting market is the NRFI/YRFI bet. These are quick-hitters in which you make a wager on the O/U total of the first inning, typically set at 0.5 runs. Thus, the bet is coined as No Run First Inning or Yes Run First Inning. No need to wait a couple of hours to cash a bet when it could be done in 20 minutes or less.

First Five Innings MLB Picks

The above options, moneyline, run line, and Over/Under, can also be placed on the first five innings of a game rather than the full game. Many experienced bettors will use this approach because, typically, this will take bullpens out of the equation and make your job researching the game easier. After all, you can just focus on the starting pitchers.

MLB Picks And Parlays

If you want to combine multiple games into one mega wager, you may consider making a parlay bet. A parlay is when you pick two or more MLB games on one single betting ticket, which will increase the payout of your bet.

But it also comes with more risk, as each of those MLB picks must hit for your ticket to pay out. Our parlay calculator is a great tool to find out what your potential payout would be.

If you're looking for more MLB picks content, check out our consensus picks and prop bets pages to get your fix. While you're at it, head over to our MLB promos page to get the best bang for your buck.

MLB Player Props

Player props are a great way to hone in on an individual matchup for a game. These types of wagers will be individualized for a player: Will Shohei Ohtani hit a home run? Will Gerrit Cole get seven strikeouts? Will Paul Skenes allow two earned runs?

You simply choose whether this outcome will happen or not. Keeping up to date on daily pitching matchups and batters on a hot streak can give you a huge boost when placing player prop bets.

MLB Futures Picks

Lastly, prior to the season and even throughout the season, you can place futures bets on all the long-term awards and outcomes. You can lock in an MLB pick on who will win their division, which squad will win the World Series, or even who will win the Rookie of the Year, MVP, or Cy Young.

MLB Free Picks FAQs

When do we release our MLB picks?

Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.

What kinds of MLB picks do we make?

Covers provides free MLB picks covering many markets, including run lines, totals, moneylines, player props, and more.