MLB Picks

Get free expert and computer MLB picks for every game on April 22, 2026. With over 25 years of betting experience, our analysts and predictive models help you find the best value.

St. Louis Cardinals logo STL @ Miami Marlins logo MIA Wed, Apr 22 • 12:10 PM ET
1 Expert Pick 10 Computer Picks
Total Home Runs
Otto Lopez logo Otto Lopez o0.5 Total Home Runs (+1120)
Best Odds
Pick made: 1 hours ago
Josh Inglis image
Josh Inglis
Betting Analyst

I’m going four-digit hunting with the No. 2 hitter in the Miami Marlins lineup in a controlled environment with a plus-plus matchup. Kyle Leahy has the second-worst Blast Contact% among MLB starters this year, and it caught up to him last time out when Houston took him deep three times indoors. Among pitchers with at least 10 innings, he ranks dead last in BlastCon%. Miami isn’t known for home-run power, but Otto Lopez stands out at a massive price. He’s being priced like a No. 8 hitter with no pop, but he’s among the team leaders in power metrics and sits well above league average in key home-run indicators. This may be the best pitching matchup for dingers on the board. The St. Louis Cardinals could also be without key bullpen arms, and they already rank 29th in xFIP among all MLB bullpens, adding to the appeal.

Total Hits
Nathan Church logo
Nathan Church u0.5 Total Hits (+184)
Projection 0.84
Best Odds
Pick made: 26 minutes ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Nathan Church in the 24th percentile when it comes to his overall offensive talent.. Nathan Church is penciled in 7th in the batting order in today's game.. When starting against a northpaw this year, Nathan Church has been lifted for a pinch-hitter 16% of the time.. The 4th-deepest RF dimensions among all stadiums are found in LoanDepot Park.. LoanDepot Park's elevation is near sea-level, one of the lowest among all major league parks, which generally leads to lower offensive output.
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Houston Astros logo HOU @ Cleveland Guardians logo CLE Wed, Apr 22 • 1:10 PM ET
10 Computer Picks
Total Bases
Yordan Alvarez logo
Yordan Alvarez o1.5 Total Bases (+105)
Projection 2.04
Best Odds
Pick made: 3 hours ago
EV Model Rating
Star rating: 4 out of 5
According to the leading projection system (THE BAT X), Yordan Alvarez ranks as the 2nd-best batter in the league.. Yordan Alvarez is projected to hit 2nd in the batting order today.. The #3 field in baseball for boosting base hits to LHB, per the leading projection system (THE BAT), is Progressive Field.. Built 673 feet above sea level, Progressive Field has the 7th-highest elevation among all parks, which tends to lead to higher offensive output.. Humid weather has a small yet noteworthy link with more offense (and fewer whiffs), and the weather report calls for the 3rd-most humidity on the slate at 76%.
Total Bases
Kyle Manzardo logo
Kyle Manzardo u1.5 Total Bases (-230)
Projection 0.68
Best Odds
Pick made: 40 minutes ago
EV Model Rating
Star rating: 3 out of 5
Kyle Manzardo has been pinch hit for 23% of the time when starting against a righty hurler this year.. In Major League Baseball, the 4th-tallest fences are at Progressive Field.. Kyle Manzardo's ability to hit the ball at a HR-optimizing launch angle (between 23° and 34°) has declined from last year to this one, going from 18.7% to 11.4%.. With a .219 Expected Batting Average (an advanced metric created by the leading projection system (THE BAT X) utilizing Statcast data) since the start of last season , Kyle Manzardo finds himself in the 13th percentile.. Kyle Manzardo has put up a .270 BABIP since the start of last season, ranking in the 20th percentile.
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Cincinnati Reds logo CIN @ Tampa Bay Rays logo TB Wed, Apr 22 • 1:10 PM ET
10 Computer Picks
Total Hits
Cedric Mullins logo
Cedric Mullins u0.5 Total Hits (+150)
Projection 0.71
Best Odds
Pick made: 6 minutes ago
EV Model Rating
Star rating: 3 out of 5
Cedric Mullins's BABIP ability is projected in the 4th percentile by the leading projection system (THE BAT X).. Cedric Mullins is projected to hit 6th in the lineup in today's game.. The #4 ballpark in the game for suppressing BABIP to LHB, via the leading projection system (THE BAT), is Tropicana Field.. Brandon Williamson will have the benefit of the platoon advantage against Cedric Mullins today.. Extreme groundball hitters like Cedric Mullins generally hit worse against extreme groundball pitchers like Brandon Williamson.
Total Hits
Ryan Vilade logo
Ryan Vilade u0.5 Total Hits (+130)
Projection 0.68
Best Odds
Pick made: 4 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Ryan Vilade in the 12th percentile when assessing his overall offensive ability.. The leading projection system (THE BAT) profiles Tropicana Field as the 4th-worst venue in the game for righty BABIP.. Ryan Vilade hits many of his flyballs to center field (38.6% — 89th percentile) but may find it hard to clear MLB's 9th-deepest CF fences in today's matchup.. Ryan Vilade's footspeed has fallen off this season. His 27.54 ft/sec Statcast Sprint Speed last season sits at 26.69 ft/sec now.. Sporting a .187 Expected Batting Average (an advanced metric created by the leading projection system (THE BAT X) based on Statcast data) since the start of last season , Ryan Vilade grades out in the 16th percentile.
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Baltimore Orioles logo BAL @ Kansas City Royals logo KC Wed, Apr 22 • 2:10 PM ET
3 Expert Picks 10 Computer Picks
Total
Baltimore Orioles logo Kansas City Royals logo u9.5 (-126)
Best Odds
Pick made: 3 hours ago
Phil Naessens image
Phil Naessens
Betting Analyst

Wacha may be outperforming his metrics, but his 23.5% strikeout rate and 33% chase rate are legitimate, and Baltimore's lineup punches out 25% of the time against right-handers. 

Kansas City's bullpen may be a disaster, but they won't be tested much if Wacha deals deep into the game. Kansas City's hacky lineup will swing early and often against Bassitt, which should help the struggling Orioles starter.

With two pitchers doing just enough against two aggressive lineups, runs might be hard to come by. Take the Under.

Moneyline
Baltimore Orioles logo BAL (+115)
Best Odds
Pick made: 3 hours ago
Phil Naessens image
Phil Naessens
Betting Analyst

The Baltimore Orioles lineup is already rolling, scoring 12 runs in this series, and this is not a soft landing spot. The Orioles also hold a clear bullpen edge, with a reliable relief group compared to the Kansas City Royals' struggles. 

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Toronto Blue Jays logo TOR @ Los Angeles Angels logo LAA Wed, Apr 22 • 3:07 PM ET
2 Expert Picks 10 Computer Picks
Total Home Runs
Daulton Varsho logo Daulton Varsho o0.5 Total Home Runs (+510)
Best Odds
Pick made: 10 minutes ago
Mike DiStefano image
Mike DiStefano
Betting Analyst

Daulton Varsho brings a lot of pop from the left side of the plate, and Soriano has given up a little bit more power to lefties than righties this season. Varsho does seem to see the sinker well out of the pitcher's hand, which is the most used pitch Soriano throws against lefties. The Jays outfielder owns a .438 batting average and a .688 slugging percentage against the pitch.

Total Bases
Vladimir Guerrero Jr. logo Vladimir Guerrero Jr. o1.5 Total Bases (+135)
Best Odds
Pick made: 12 minutes ago
Mike DiStefano image
Mike DiStefano
Betting Analyst

Vladdy is 2-for-2 with a walk in three plate appearances against Jose Soriano, and Soriano's most-used pitch is a sinker-ball, a pitch that Guerrero owns a .444 batting average with a 55% hard-hit rate against. I’m expecting Guerrero Jr. to continue this trend as he's one of baseball’s best hitters.

View 12 Picks
Athletics Athletics logo ATH @ Seattle Mariners logo SEA Wed, Apr 22 • 4:10 PM ET
1 Expert Pick 10 Computer Picks
Total Home Runs
Shea Langeliers logo Shea Langeliers o0.5 Total Home Runs (+440)
Best Odds
Pick made: an hour ago
Josh Inglis image
Josh Inglis
Betting Analyst

Let's stay indoors and bet on a bat who has already homered in two straight games in Seattle with Shea Langeliers, who has launched eight homers this year. Logan Gilbert is a flyball pitcher, which is in our favor here, and Langeliers has also seen plenty of this Seattle bullpen and took it deep last night. Ultimately, this is a play on price, and getting elite HR hitters at +EV isn't a common occurrence. The fair price is around +380. Let's back the hot stick today with great expected value. 

Total Hits
Carlos Cortes logo
Carlos Cortes u0.5 Total Hits (+135)
Projection 0.7
Best Odds
Pick made: 6 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Carlos Cortes in the 11th percentile when assessing his BABIP skill.. When starting against a right-handed starter this year, Carlos Cortes has been replaced by a pinch-hitter 47% of the time.. The leading projection system (THE BAT) profiles T-Mobile Park as the worst venue in the league for lefty batting average.. T-Mobile Park's elevation is near sea-level, one of the lowest in MLB, which generally leads to lower offensive output.. Less offense (and more strikeouts) are strongly linked with lower temperatures, and the weather report for this contest predicts the 4th-lowest temperature on the slate today at 57°.
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Milwaukee Brewers logo MIL @ Detroit Tigers logo DET Wed, Apr 22 • 6:40 PM ET
10 Computer Picks
Total Hits
Sal Frelick logo
Sal Frelick u0.5 Total Hits (+185)
Projection 0.84
Best Odds
Pick made: 10 minutes ago
EV Model Rating
Star rating: 3 out of 5
Sal Frelick is penciled in 7th on the lineup card in this game.. The 2nd-deepest centerfield fences in the league are found in Comerica Park.. Playing on the road typically lowers batter metrics across the board due to the lack of home field advantage, which figures to be the case for Sal Frelick in today's matchup.. Sal Frelick has been cold in recent games, with his seasonal exit velocity of 85.1-mph dropping to 81.1-mph in the last 7 days.. Sal Frelick's ability to hit the ball at a base hit-optimizing launch angle (between -4° and 26°) has decreased from last season to this one, falling from 41.1% to 29.1%.
Total Bases
Kerry Carpenter logo
Kerry Carpenter o1.5 Total Bases (+170)
Projection 1.55
Best Odds
Pick made: 24 minutes ago
EV Model Rating
Star rating: 4 out of 5
When assessing his home run talent, Kerry Carpenter ranks in the 96th percentile according to the leading projection system (THE BAT X).. The leading projection system (THE BAT) profiles Comerica Park as the 10th-best ballpark in the game for run-scoring.. Among all stadiums, Comerica Park has the 2nd-lowest average fence height.. Built 602 feet above sea level, Comerica Park has the 9th-highest elevation among all parks, which tends to lead to better offense.. Kerry Carpenter will hold the platoon advantage against Chad Patrick today.
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Atlanta Braves logo ATL @ Washington Nationals logo WAS Wed, Apr 22 • 6:45 PM ET
10 Computer Picks
Total Bases
CJ Abrams logo
CJ Abrams o1.5 Total Bases (+160)
Projection 1.65
Best Odds
Pick made: 34 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects CJ Abrams in the 81st percentile as it relates to his batting average skill.. CJ Abrams is penciled in 4th on the lineup card in this game.. In terms of temperature and humidity, the weather report projects for the 3rd-most favorable hitting conditions of the day.. Martin Perez will hold the platoon advantage against CJ Abrams today.. CJ Abrams pulls a lot of his flyballs (34.9% — 82nd percentile) and will have a big advantage hitting them towards MLB's 10th-shallowest RF fences in today's matchup.
Total Bases
James Wood logo
James Wood o1.5 Total Bases (+120)
Projection 1.92
Best Odds
Pick made: 6 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects James Wood as the best hitter in the game as it relates to his BABIP ability.. James Wood is projected to hit 1st on the lineup card in this game.. In Major League Baseball, Nationals Park's RF fences are the 9th-shallowest.. In terms of temperature and humidity, the weather report projects for the 3rd-most favorable hitting conditions of the day.. Martin Perez will have the handedness advantage over James Wood in today's matchup.
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New York Yankees logo NYY @ Boston Red Sox logo BOS Wed, Apr 22 • 6:45 PM ET
10 Computer Picks
Total Hits
Giancarlo Stanton logo
Giancarlo Stanton u0.5 Total Hits (+150)
Projection 0.76
Best Odds
Pick made: 1 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Giancarlo Stanton in the 14th percentile when estimating his BABIP skill.. Built just 16 feet above sea level, Fenway Park has one of the lowest altitudes in the league, which tends to lead to lower offensive output.. Less offense (and more strikeouts) are strongly connected with cold weather, and the weather report for this game projects the lowest temperature on the slate at 46°.. Out of all the teams playing today, the best infield defense is that of the Boston Red Sox.. Playing on the road typically diminishes hitter metrics across the board due to the lack of home field advantage, which should be the case for Giancarlo Stanton in today's game.
Total Hits
Randal Grichuk logo
Randal Grichuk u0.5 Total Hits (+130)
Projection 0.68
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Randal Grichuk in the 16th percentile when assessing his BABIP ability.. Randal Grichuk is projected to bat 6th in the lineup in today's game.. Randal Grichuk has been replaced by a pinch-hitter 45% of the time when starting against a left-handed pitcher since the start of last season.. Built just 16 feet above sea level, Fenway Park has one of the lowest altitudes in the league, which tends to lead to lower offensive output.. Less offense (and more strikeouts) are strongly connected with cold weather, and the weather report for this game projects the lowest temperature on the slate at 46°.
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Minnesota Twins logo MIN @ New York Mets logo NYM Wed, Apr 22 • 7:10 PM ET
10 Computer Picks
Total Hits
Juan Soto logo
Juan Soto u0.5 Total Hits (+180)
Projection 0.83
Best Odds
Pick made: 14 minutes ago
EV Model Rating
Star rating: 3 out of 5
The #3 stadium in Major League Baseball for suppressing base hits to LHB, via the leading projection system (THE BAT), is Citi Field.. Built just 13 feet above sea level, Citi Field has one of the lowest elevations among all parks, which usually leads (as a rule of thumb) to worse offense.. Cold weather is strongly correlated with less offense (and more strikeouts), and the weather report projects the 3rd-coldest temperature on the slate today at 53°.. The wind projects to be blowing in from CF at 8.1-mph in this match-up, the most-favorable of the day for pitchers.. Connor Prielipp will have the handedness advantage against Juan Soto in today's matchup.
Total Hits
Tyrone Taylor logo
Tyrone Taylor u0.5 Total Hits (-105)
Projection 0.55
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 3 out of 5
Tyrone Taylor is projected to bat 9th in the batting order today.. Citi Field ranks as the #29 venue in MLB for RHB base hits, according to the leading projection system (THE BAT).. Built just 13 feet above sea level, Citi Field has one of the lowest elevations among all parks, which usually leads (as a rule of thumb) to worse offense.. Cold weather is strongly correlated with less offense (and more strikeouts), and the weather report projects the 3rd-coldest temperature on the slate today at 53°.. The wind projects to be blowing in from CF at 8.1-mph in this match-up, the most-favorable of the day for pitchers.
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Philadelphia Phillies logo PHI @ Chicago Cubs logo CHC Wed, Apr 22 • 7:40 PM ET
2 Expert Picks 10 Computer Picks
Spread
Chicago Cubs logo CHC -1.5 (+128)
Best Odds
Pick made: an hour ago
Neil Parker image
Neil Parker
Betting Analyst

The Cubbies are cruising along a 10-3 heater while scoring 6.4 runs per game and pacing the majors in wOBA. Chicago has also covered the run line in eight of the highlighted 10 wins and 14 of the past 22 at Wrigley Field. Philadelphia is projected to go with opener Kyle Backhus, and then have veteran Taijuan Walker in bulk relief, which sets up poorly for the Phillies. Walker has been saddled with a 5.08 ERA and 4.90 xFIP alongside the fourth lowest strikeout-to-walk rate (7.9%) in the majors across four seasons with the club, after all.

Total RBIs
Nico Hoerner logo Nico Hoerner o0.5 Total RBIs (+180)
Best Odds
Pick made: an hour ago
Quinn Allen image
Quinn Allen
Betting Analyst

Hoerner has four RBI in his last five games, and he is hitting .347 in April. Hoerner ranks third in the Majors in RBI. He is 1-1 lifetime against Kyle Backhus with a pair of RBI. 

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Pittsburgh Pirates logo PIT @ Texas Rangers logo TEX Wed, Apr 22 • 8:05 PM ET
10 Computer Picks
Total Bases
Brandon Lowe logo
Brandon Lowe u1.5 Total Bases (-159)
Projection 0.9
Best Odds
Pick made: 40 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT) profiles Globe Life Field as the worst field in the league for run-scoring.. The 6th-deepest centerfield dimensions in the league are found in Globe Life Field.. Among every team today, the 4th-strongest infield defense is that of the Texas Rangers.. Playing on the road typically lowers batter stats across the board due to the lack of home field advantage, which ought to be the case for Brandon Lowe today.. Brandon Lowe's average exit velocity has dropped off this year; his 91-mph mark last year has fallen off to 86.2-mph.
Total Bases
Oneil Cruz logo
Oneil Cruz u1.5 Total Bases (-150)
Projection 0.96
Best Odds
Pick made: 40 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT) profiles Globe Life Field as the worst field in the league for run-scoring.. In today's matchup, Oneil Cruz is at a disadvantage facing the league's 6th-deepest CF center field fences given that he hits his flyballs towards center field at a 38.6% rate (89th percentile).. Among every team today, the 4th-strongest infield defense is that of the Texas Rangers.. Playing on the road generally diminishes hitter stats in all categories due to the lack of home field advantage, which should be the case for Oneil Cruz in today's matchup.. Oneil Cruz has been lucky this year, notching a .384 wOBA despite the leading projection system (THE BAT X) estimating his true talent level to be .346 — a .038 difference.
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San Diego Padres logo SD @ Colorado Rockies logo COL Wed, Apr 22 • 8:40 PM ET
2 Expert Picks 10 Computer Picks
Spread
San Diego Padres logo SD -1.5 (+100)
Best Odds
Pick made: 1 hours ago
Josh Inglis image
Josh Inglis
Betting Analyst

Don’t let the sub-4.00 ERA from Tomoyuki Sugano fool you. He’s been one of the luckiest pitchers to start the year, carrying a 7.71 xERA vs. a 3.92 ERA. He’s getting hit hard, running a low BABIP, and stranding 88% of runners — clear regression signals. The San Diego Padres, sitting at 16-7 SU, are well-positioned to stack runs and win by multiple runs. A late comeback is unlikely with a fully available bullpen, including Mason Miller, who was rested yesterday. The fair price on the moneyline sits around -195 versus a -165 market, and the run line breakeven is closer to -130, making +100 strong value. The Rockies were just shut out last night, and I'm hoping that struggle continues into today.

Total Home Runs
Fernando Tatis Jr. logo Fernando Tatis Jr. o0.5 Total Home Runs (+400)
Best Odds
Pick made: 1 hours ago
Josh Inglis image
Josh Inglis
Betting Analyst

I had this start circled for five days. Tomoyuki Sugano owns a sub-4.00 ERA, but his xERA is closer to 8.00. He’s been wildly lucky while allowing the eighth-worst Blast Contact% among starters, and he’s also posted one of the worst HR/9 rates over the last two seasons. In short, the San Diego Padres are a great place to look for dingers on Wednesday at Coors Field, especially with poor hitting weather elsewhere. Fernando Tatis Jr. is +400 to go deep with a fair price around +330, per Covers projections powered by THE BAT. He’s the best +EV home run on the board this morning. It’s surprising he hasn’t gone deep yet, but that’s why the price is discounted. He leads the team with a 27.5% Blast Contact% rate, and it feels like a matter of time before that breaks through.

View 12 Picks
Chicago White Sox logo CHW @ Arizona Diamondbacks logo AZ Wed, Apr 22 • 9:40 PM ET
1 Expert Pick 10 Computer Picks
Total RBIs
Munetaka Murakami logo Munetaka Murakami o0.5 Total RBIs (+150)
Best Odds
Pick made: an hour ago
Quinn Allen image
Quinn Allen
Betting Analyst

The slugger has eight RBI across his last four games, and he’s also gone deep in four straight appearances. Murakami cannot be stopped. He was 3-for-5 in Tuesday’s series opener against the Arizona Diamondbacks with a home run, an RBI, and three hits.

Total Bases
Everson Pereira logo
Everson Pereira u1.5 Total Bases (-180)
Projection 0.86
Best Odds
Pick made: 6 hours ago
EV Model Rating
Star rating: 3 out of 5
The league's 10th-highest average fence height can be found at Chase Field.. Everson Pereira hits a lot of his flyballs to center field (38.3% — 85th percentile) and has the misfortune of hitting them in the direction of baseball's 3rd-deepest CF fences today.. The Arizona Diamondbacks outfield defense profiles as the strongest out of all the teams today.. Everson Pereira will be at a disadvantage playing as a visiting player in today's matchup.. Everson Pereira's speed has fallen off this season. His 28.31 ft/sec Statcast Sprint Speed last year sits at 26.88 ft/sec now.
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Los Angeles Dodgers logo LAD @ San Francisco Giants logo SF Wed, Apr 22 • 9:45 PM ET
4 Expert Picks 10 Computer Picks
Strikeouts Thrown
Shohei Ohtani logo Shohei Ohtani o6.5 Strikeouts Thrown (-122)
Best Odds
Pick made: an hour ago
Quinn Allen image
Quinn Allen
Betting Analyst

Ohtani racked up 10 Ks in his last start against the New York Mets. While San Fran is around the middle of the pack in team strikeouts, they’re swinging and missing a lot more lately, striking out nearly 10 times per game across their previous three contests. Also, Ohtani has collected 16 Ks in 12 innings of work at home. 

Strikeouts Thrown
Shohei Ohtani logo Shohei Ohtani o6.5 Strikeouts Thrown (-122)
Best Odds
Pick made: an hour ago
Quinn Allen image
Quinn Allen
Betting Analyst

Ohtani racked up 10 Ks in his last start against the New York Mets. While San Fran is around the middle of the pack in team strikeouts, they’re swinging and missing a lot more lately, striking out nearly 10 times per game across their previous three contests. Also, Ohtani has collected 16 Ks in 12 innings of work at home. 

View 14 Picks

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