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MLB Picks

Get free expert and computer MLB picks for every game on Sept. 26, 2026.

New Computer Picks powered by Odds Shark

Predicted Score

TEX logo
TEX
TEX

4.66 @ 3.75

MIN
MIN logo
MIN

Rangers vs Twins · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TEX logo
TEX
TEX

4.66

-122

o7.5 -115

-1.5 +140

MIN logo
MIN
MIN

3.75

+112

u8.0 -118

+1.5 -148

Cleveland @ Kansas City
Matchup Stats

Predicted Score

CLE logo
CLE
CLE

4.56 @ 4.69

KC
KC logo
KC

Guardians vs Royals · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CLE logo
CLE
CLE

4.56

-105

o8.0 -120

-1.5 +150

KC logo
KC
KC

4.69

+102

u8.5 -115

+1.5 -157

Top Projection Salvador Perez o0.5 Total RBIs (+191)
o0.5+191
Colorado @ Chi. White Sox
Matchup Stats

Predicted Score

COL logo
COL
COL

4.06 @ 4.87

CHW
CHW logo
CHW

Rockies vs White Sox · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

COL logo
COL
COL

4.06

+215

o7.5 -139

+2.0 -124

CHW logo
CHW
CHW

4.87

-230

u8.5 -125

-2.0 +102

Top Projection Mickey Moniak o1.5 Total Bases (+250)
o1.5+250
St. Louis @ Milwaukee
Matchup Stats

Predicted Score

STL logo
STL
STL

3.66 @ 3.99

MIL
MIL logo
MIL

Cardinals vs Brewers · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

STL logo
STL
STL

3.66

+141

o7.5 -109

+1.5 -148

MIL logo
MIL
MIL

3.99

-152

u7.5 -102

-1.5 +135

Top Projection Dustin May o3.5 Strikeouts Thrown (+150)
o2.5-125
Tampa Bay @ Philadelphia
Matchup Stats

Predicted Score

TB logo
TB
TB

4.33 @ 4.15

PHI
PHI logo
PHI

Rays vs Phillies · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TB logo
TB
TB

4.33

+106

o6.5 -125

+1.5 -200

PHI logo
PHI
PHI

4.15

-110

u7.0 -115

-1.5 +178

Top Projection Bryce Harper o0.5 Total RBIs (+213)
o0.5+230
Arizona @ San Diego
Matchup Stats

Predicted Score

AZ logo
AZ
AZ

4.73 @ 4.13

SD
SD logo
SD

Diamondbacks vs Padres · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

AZ logo
AZ
AZ

4.73

+110

o7.5 -109

+1.5 -200

SD logo
SD
SD

4.13

-117

u7.5 -105

-1.5 +170

Houston @ Athletics
Matchup Stats

Predicted Score

HOU logo
HOU
HOU

5.85 @ 5.37

ATH
ATH logo
ATH

Astros vs Athletics · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

HOU logo
HOU
HOU

5.85

-155

o9.5 -115

-1.5 +100

ATH logo
ATH
ATH

5.37

+140

u10.0 -115

+1.5 -111

Top Projection Shea Langeliers o1.5 Hits+Runs+RBIs (-115)
o1.5-110
LA Angels @ Seattle
Matchup Stats

Predicted Score

LAA logo
LAA
LAA

3.11 @ 4.46

SEA
SEA logo
SEA

Angels vs Mariners · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAA logo
LAA
LAA

3.11

+140

o7.0 -120

+1.5 -143

SEA logo
SEA
SEA

4.46

-155

u7.5 -115

-1.5 +140

Top Projection J.P. Crawford o0.5 Total RBIs (+360)
o0.5+360
NY Mets @ Washington
Matchup Stats

Predicted Score

NYM logo
NYM
NYM

4.84 @ 4.26

WAS
WAS logo
WAS

Mets vs Nationals · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

NYM logo
NYM
NYM

4.84

-109

o8.0 -115

-1.5 +155

WAS logo
WAS
WAS

4.26

-108

u8.5 -120

+1.5 -180

Baltimore @ NY Yankees
Matchup Stats
LA Dodgers @ San Francisco
Matchup Stats

Predicted Score

LAD logo
LAD
LAD

5.72 @ 3.19

SF
SF logo
SF

Dodgers vs Giants · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAD logo
LAD
LAD

5.72

--

--

--

SF logo
SF
SF

3.19

--

--

--

Houston @ Athletics
Matchup Stats

Predicted Score

HOU logo
HOU
HOU

6.51 @ 5.55

ATH
ATH logo
ATH

Astros vs Athletics · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

HOU logo
HOU
HOU

6.51

--

--

--

ATH logo
ATH
ATH

5.55

--

--

--

Tampa Bay @ Philadelphia
Matchup Stats

Predicted Score

TB logo
TB
TB

3.72 @ 4.83

PHI
PHI logo
PHI

Rays vs Phillies · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TB logo
TB
TB

3.72

+112

o7.0 -120

+1.5 -185

PHI logo
PHI
PHI

4.83

-130

u7.5 -120

-1.5 +170

Chi. Cubs @ Boston
Matchup Stats

Predicted Score

CHC logo
CHC
CHC

4.76 @ 4.66

BOS
BOS logo
BOS

Cubs vs Red Sox · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHC logo
CHC
CHC

4.76

--

--

--

BOS logo
BOS
BOS

4.66

--

--

--

Cincinnati @ Toronto
Matchup Stats

Predicted Score

CIN logo
CIN
CIN

3.88 @ 4.53

TOR
TOR logo
TOR

Reds vs Blue Jays · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CIN logo
CIN
CIN

3.88

--

--

--

TOR logo
TOR
TOR

4.53

--

--

--

Atlanta @ Miami
Matchup Stats

Predicted Score

ATL logo
ATL
ATL

4.51 @ 4.25

MIA
MIA logo
MIA

Braves vs Marlins · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

ATL logo
ATL
ATL

4.51

-109

o8.5 -120

-1.5 +160

MIA logo
MIA
MIA

4.25

-110

u9.0 -115

+1.5 -170

Colorado @ Chi. White Sox
Matchup Stats

Predicted Score

COL logo
COL
COL

3.95 @ 4.63

CHW
CHW logo
CHW

Rockies vs White Sox · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

COL logo
COL
COL

3.95

+181

o8.5 -114

+1.5 -110

CHW logo
CHW
CHW

4.63

-213

u8.5 -104

-1.5 -105

Texas @ Minnesota
Matchup Stats

Predicted Score

TEX logo
TEX
TEX

4.51 @ 3.95

MIN
MIN logo
MIN

Rangers vs Twins · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TEX logo
TEX
TEX

4.51

--

--

--

MIN logo
MIN
MIN

3.95

--

--

--

Cleveland Guardians image thumbnail CLE @ Kansas City Royals image thumbnail KC Sat, Sep 26 • 7:10 PM ET
Total Home Runs
Vinnie Pasquantino logo Vinnie Pasquantino o0.5 Total Home Runs (+434)
Best Odds
Pick made: 9 hours ago
Todd Cordell logo
Todd Cordell
Betting Analyst

Vinnie Pasquantino is hammering Tanner Bibee’s pitch mix, hitting .303 with a .242 ISO and 53.6% hard hit rate over the last 25 games when facing right-handed fastballs, cutters, and changeups.

Those are Bibee’s most used pitches, and account for well over 70% of what he throws to lefties.

Pasquantino has a shockingly good track record against Bibee. He is 11-18 with 10 hard hit balls and five extra base hits, two of which went the distance.

Total
Cleveland Guardians image thumbnail Kansas City Royals image thumbnail u8.5 (-119)
Best Odds
Pick made: 9 hours ago
Todd Cordell logo
Todd Cordell
Betting Analyst

The Under is playable to 55%.

Tanner Bibee has pitched well against Kansas City this season, posting a 3.48 xERA – nearly a full run below his season output of 4.46.

Michael Wacha is an innings eater who held the Guardians to three runs over 23 innings this season. He’ll likely pitch deep into this one, giving the Guardians less time to produce against the Royals’ underwhelming bullpen.

View 14 Picks
Colorado Rockies image thumbnail COL @ Chicago White Sox image thumbnail CHW Sat, Sep 26 • 7:10 PM ET
Total Home Runs
Miguel Vargas logo Miguel Vargas o0.5 Total Home Runs (+337)
Best Odds
Pick made: 7 hours ago
Shawn Krest logo
Shawn Krest
Betting Analyst

Vargas has been Chicago's hottest power hitter, with an OPS+ nearly two and a half times league average over the past week. He also has hit lefthanders better than righties and should have a chance to take Quintana out. 

Total
Colorado Rockies image thumbnail Chicago White Sox image thumbnail o8.5 (-101)
Best Odds
Pick made: 7 hours ago
Shawn Krest logo
Shawn Krest
Betting Analyst

Colorado starter Jose Quintana has battled elbow trouble and has one of the slowest fastballs in MLB. Chicago has been scoring runs and Colorado allowing them lately. The Rockies also match up well with Sox starter Davis Martin. 

View 13 Picks
St. Louis Cardinals image thumbnail STL @ Milwaukee Brewers image thumbnail MIL Sat, Sep 26 • 7:10 PM ET
Total Home Runs
Ivan Herrera logo Ivan Herrera o0.5 Total Home Runs (+750)
Best Odds
Pick made: 13 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Play up to 16%. Ivan Herrera has shown serious pop lately, homering three times in his last six games while carrying a .417 ISO. His 23.1% barrel rate and 46.2% fly-ball rate add to the appeal against Dustin May, who has allowed 1.96 HR/9 across his last five outings.

Strikeouts Thrown
Quinn Mathews logo
Quinn Mathews o4.5 Strikeouts Thrown (-120)
Projection 5.48
Best Odds
Pick made: 15 seconds ago
EV Model Rating
Star rating: 3 out of 5
The Milwaukee Brewers have 3 batters in their projected lineup today with a high (i.e. over 27%) underlying K% (according to the leading projection system, THE BAT X) (Jake Bauers, Garrett Mitchell, David Hamilton).. The leading projection system (THE BAT) profiles American Family Field as the 4th-best ballpark in Major League Baseball for strikeouts.. Less offense (and more strikeouts) are strongly correlated with lower temperatures, and the weather report for this game predicts the 3rd-lowest temperature of all games on the slate today at 59°.. Considering the 0.65 difference between Quinn Mathews's 7.92 K/9 and his 8.57 estimated true talent K/9 (via the leading projection system, THE BAT), it's safe to say he's been one of the least fortunate pitchers in Major League Baseball this year as it relates to strikeouts and ought to positively regress the rest of the season.
View 11 Picks
Tampa Bay Rays image thumbnail TB @ Philadelphia Phillies image thumbnail PHI Sat, Sep 26 • 7:15 PM ET
Total Home Runs
Kyle Schwarber logo Kyle Schwarber o0.5 Total Home Runs (+301)
Best Odds
Pick made: 3 hours ago
Jason Ence logo
Jason Ence
Betting Analyst

Kyle Schwarber will have the handed advantage over Griffin Jax, and has posted a .400 ISO at home against RHP this season. Schwarber also had a 50% hard-hit rate in the month of September. If anybody's gonna get one through the wind tonight, Schwarber is the best option to do so. 

Total
Tampa Bay Rays image thumbnail Philadelphia Phillies image thumbnail u6.5 (+112)
Best Odds
Pick made: 3 hours ago
Jason Ence logo
Jason Ence
Betting Analyst

I'm backing the Under to 51% in a game that will likely see weather delays—and possibly an early end. Winds will be blowing in from center field at up to 36 mph, which will help the best two bullpens in the majors at limiting hard contact over the past week. With rain chances jumping to 90% after midnight, a long rain delay will likely see this game halted prematurely. 

View 13 Picks
Arizona Diamondbacks image thumbnail AZ @ San Diego Padres image thumbnail SD Sat, Sep 26 • 8:40 PM ET
Total Home Runs
Nolan Arenado logo Nolan Arenado o0.5 Total Home Runs (+525)
Best Odds
Pick made: 13 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Play up to 20%. Nolan Arenado is locked in at the plate, going deep four times over his last six games while posting a .520 ISO. Walker Buehler has allowed 2.28 HR/9 over the last month, and Arenado has already taken him deep twice in his career.

Moneyline
Arizona Diamondbacks image thumbnail AZ (+106)
Best Odds
Pick made: yesterday
Phil Naessens logo
Phil Naessens
Betting Analyst

Arizona has rattled off five straight wins to stay alive in the wild-card race and gives the ball to Corbin Burnes in a must-win game. San Diego has already punched their postseason ticket, while the Diamondbacks offense has caught fire over the last fortnight (128 wRC+, .500 SLG, 3.49 bullpen SIERA). Getting Burnes backed by high urgency against Walker Buehler provides the premier late-game value on the board.

View 12 Picks
Houston Astros image thumbnail HOU @ Athletics Athletics image thumbnail ATH Sat, Sep 26 • 9:40 PM ET
Total Bases
Shea Langeliers logo
Shea Langeliers o1.5 Total Bases (+119)
Projection 2.2
Best Odds
Pick made: 15 seconds ago
EV Model Rating
Star rating: 4 out of 5
When assessing his home run ability, Shea Langeliers ranks in the 96th percentile according to the leading projection system (THE BAT X).. Shea Langeliers is projected to hit 3rd on the lineup card in this game.. Sutter Health Park profiles as the #1 park in the league for right-handed home runs, per the leading projection system (THE BAT).. Sutter Health Park has the 2nd-shortest average fence height among all major league stadiums.. A correlation exists between high heat and more offense (and fewer Ks), and this game is predicted to have the hottest weather on the slate at 87°.
Total Bases
Henry Bolte logo
Henry Bolte o1.5 Total Bases (+119)
Projection 1.83
Best Odds
Pick made: 18 minutes ago
EV Model Rating
Star rating: 3 out of 5
When estimating his BABIP skill, Henry Bolte is projected as the best hitter in the game by the leading projection system (THE BAT X).. Henry Bolte has primarily hit in the back-half of the batting order this season (50% of the time), but he is projected to bat 1st on the lineup card in this matchup.. Sutter Health Park profiles as the #1 park in the league for right-handed home runs, per the leading projection system (THE BAT).. Sutter Health Park has the 2nd-shortest average fence height among all major league stadiums.. A correlation exists between high heat and more offense (and fewer Ks), and this game is predicted to have the hottest weather on the slate at 87°.
View 10 Picks
Los Angeles Angels image thumbnail LAA @ Seattle Mariners image thumbnail SEA Sat, Sep 26 • 9:40 PM ET
Total Home Runs
Randy Arozarena logo Randy Arozarena o0.5 Total Home Runs (+475)
Best Odds
Pick made: 13 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Play up to 20%. Randy Arozarena’s recent contact profile points to more power, with a 57.1% hard-hit rate and 14.3% barrel rate over the last week. Ryan Johnson has allowed 1.79 HR/9 on the road, while the Angels’ bullpen has also been vulnerable to the long ball.

Total Hits
Dominic Canzone logo
Dominic Canzone u0.5 Total Hits (+170)
Projection 0.85
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 3 out of 5
T-Mobile Park grades out as the #30 venue in the league for lefty batting average, via the leading projection system (THE BAT).. Built just 17 feet above sea level, T-Mobile Park has one of the lowest elevations in MLB, which usually leads (as a rule of thumb) to lower offensive output.. In terms of temperature and humidity, the weather forecast expects the 2nd-most favorable pitching conditions on the slate today.. Out of every team on the slate today, the 2nd-strongest infield defense is that of the the Los Angeles Angels.
View 11 Picks

What Is An MLB Computer Pick?

MLB picks are bet suggestions based on our computer's assessment of the game. Tons of betting data goes into a computer pick, including pitching matchups, injury reports, analytics, and even recent betting trends.

How To Use MLB Computer Picks

You can use the tables above to help with your bets during the MLB season. The first section includes free, computer-generated picks for daily Major League Baseball games. Baseball bettors can choose to follow the computer, fade the computer, or simply use our computer picks as one element of their betting strategy.

This page also tees up access to deeper betting trends. For example, if a club's run line is favored, you can check their ATS trends, potentially opening up some quality underdog bets.

If you're ready to get started with MLB betting, visit our dedicated page highlighting the best MLB betting sites.

Moneyline

This is the most common and easiest wager for a bettor to make when it comes to MLB picks. Basically, to win an MLB moneyline pick, you just have to choose which team will win the game.

It's simple: if you bet the White Sox moneyline over the Red Sox and Chicago wins, you win your bet.

Run line

The run line is another name for a point spread that you may be more familiar with in NBA and NFL betting. A point spread varies in the NFL and NBA from as little as 0.5 points up to double-digit spreads. A baseball run line is almost always a 1.5-point spread.

The favorite will be -1.5 while the underdog will be +1.5. At the end of the game, if you take away 1.5 runs from the favorite or add 1.5 runs to the underdog and they end up winning the game, you win your MLB pick against the spread.

Totals (Over/Under)

Another common wager is to bet on the total in baseball, which is a bet on the total runs scored in the baseball game. You are simply choosing whether the final score will be Over or Under that total. Betting the Over/Under on a matchup is a great way to get started in MLB score predictions.

Free Computer Picks by Odds Shark

More MLB Picks & Betting Tools

NRFI/YRFI MLB Picks

A new and emerging MLB betting market is the NRFI/YRFI bet. These are quick-hitters in which you make a wager on the O/U total of the first inning, typically set at 0.5 runs. Thus, the bet is coined as No Run First Inning or Yes Run First Inning. No need to wait a couple of hours to cash a bet when it could be done in 20 minutes or less.

First Five Innings MLB Picks

The above options, moneyline, run line, and Over/Under, can also be placed on the first five innings of a game rather than the full game. Many experienced bettors will use this approach because, typically, this will take bullpens out of the equation and make your job researching the game easier. After all, you can just focus on the starting pitchers.

MLB Picks And Parlays

If you want to combine multiple games into one mega wager, you may consider making a parlay bet. A parlay is when you pick two or more MLB games on one single betting ticket, which will increase the payout of your bet.

But it also comes with more risk, as each of those MLB picks must hit for your ticket to pay out. Our parlay calculator is a great tool to find out what your potential payout would be.

If you're looking for more MLB picks content, check out our consensus picks and prop bets pages to get your fix. While you're at it, head over to our MLB promos page to get the best bang for your buck.

MLB Player Props

Player props are a great way to hone in on an individual matchup for a game. These types of wagers will be individualized for a player: Will Shohei Ohtani hit a home run? Will Gerrit Cole get seven strikeouts? Will Paul Skenes allow two earned runs?

You simply choose whether this outcome will happen or not. Keeping up to date on daily pitching matchups and batters on a hot streak can give you a huge boost when placing player prop bets.

MLB Futures Picks

Lastly, prior to the season and even throughout the season, you can place futures bets on all the long-term awards and outcomes. You can lock in an MLB pick on who will win their division, which squad will win the World Series, or even who will win the Rookie of the Year, MVP, or Cy Young.

MLB Free Picks FAQs

When do we release our MLB picks?

Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.

What kinds of MLB picks do we make?

Covers provides free MLB picks covering many markets, including run lines, totals, moneylines, player props, and more.