Inter Milan vs Barcelona Predictions, Picks & Odds for Tuesday’s Champions League Match

With it all the play for on Tuesday, both Inter Milan and Barcelona will be hoping to take the fight to the other team. One player who should continue to dazzle is Lamine Yamal. Find out why he's the subject of Tuesday's best bet.

Emanuel Rosu - Betting Analyst at Covers.com
Emanuel Rosu • Betting Analyst
May 6, 2025 • 09:34 ET • 4 min read
Lamine Yamal of FC Barcelona during the UEFA Champions League match.
Photo By - Imagn Images. Lamine Yamal of FC Barcelona during the UEFA Champions League match.

After an all-time Champions League classic in the first leg, these two European giants promise to offer another game to remember at the iconic San Siro in Milan.

It ended 3-3 in Barcelona, and both Inter and Barca have plenty of winning cards to throw on the table. Barcelona have a flamboyant attack, while Inter are solid as a rock and would be tough to crack no matter who they would face. I will opt for a prop bet on in-form Barcelona winger Lamine Yamal, looking for another top delivery from the youngster.

Here are my Inter Milan vs. Barcelona predictions and free betting picks for Tuesday, May 6.

Inter Milan vs Barcelona picks and predictions

My Inter Milan vs Barcelona best bet: Lamine Yamal 2+ shots on target (+172 at Betano)

Lamine Yamal averages 1.66 shots on target per match in the Champions League. To say the 17-year-old is influential for Barcelona would be an understatement. Yamal is one of the hottest topics in world football's elite, as he was often unplayable among the big guns despite his young age.

Given that this match can go in either direction, I am focusing on Lamine's performance to get a nice return. If you feel adventurous, know that Betano pays +590 for Lamine shooting on goal three or more times.

In the first leg last week, Barcelona had no fewer than 19 attempts, with 10 of them coming on goal. They now play away, but their attacking approach should stay the same, based on manager Hansi Flick's principles. And with Yamal in form and hungry for glory, he should be involved in many of Barcelona's attacks on Tuesday night.

Inter Milan vs Barcelona same-game parlay (SGP)

Lamine Yamal 2+ shots on target

Raphinha 2+ shots on target

Over 9.5 corners

Alongside Yamal and Lewandowski, when you think of Barcelona scoring, you can't ignore Raphinha. Especially in the Champions League, he's been flying this season. He hit the net 12 times. He's only behind Dortmund's Guirassy in the top scorer's list and looks to score to extend his tally in order to win the competition's Golden Boot. He's been so close to scoring a fabulous goal last week!

His shot from outside the box in the 65th minute hit the crossbar, then bounced into the net after touching Inter's keeper Sommer. Unluckily for Raphinha, it counted as an own goal. We'll add him to our parlay, also counting on his shots, just like in Yamal's case. Up to now, Raphinga averages 1.5 shots on target per game.

Set-pieces could play an important role on Tuesday night in Milan, thinking that both sides have quality players to provoke free-kicks and corners. Barcelona averages almost five corners per game, while Inter stands just below three. I'll go for over 9.5 corners in this match to round up a really nice +1100 paycheck for Tuesday's Champions League soccer.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Inter Milan vs Barcelona odds

Inter Milan vs Barcelona live odds

Inter Milan vs Barcelona opening odds

  • Moneyline: Inter Milan +180 | Barcelona +135
  • Draw: +275
  • Over/Under: Over 2.5 -213 | Under 2.5 +170

How to watch Inter Milan vs Barcelona

Location Stadio Giuseppe Meazza, Milan, Italy
Date Tuesday, 5-6-2025
Time 3:00 p.m. ET
TV CBS, Paramount+
Weather Temps in the 50s, with minimal wind and some rain expected.

Inter Milan vs Barcelona key injuries

Inter Milan: Benjamin Pavard CB (Out).
Barcelona: Jules Kounde RB (Out), Alejandro Balde LB (Out), Marc Casado CM (Out), Marc Bernal CM (Out), Robert Lewandowski ST (Questionable).

Not intended for use in MA.
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Emanuel Rosu
Betting Analyst

Emanuel Roșu studied public administration but only to have a degree in something. He was always passionate about football. Writing about it, that is, as we've seen him play and he should feel fortunate he never took that road. He is based in Bucharest and has reported on Champions League, Europa League, and European Championship matches for various media outlets in Europe. He wrote stories for The Guardian, BBC, FourFourTwo, and many more. He represents Romania in the vote for the "Ballon d'Or", the most important individual trophy in world football.

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