Week 7 wakes up with an interesting non-conference clash on Thursday Night Football.
The New England Patriots roll into Chi-Town to take on the Chicago Bears at Soldier Field, and I’ve got three Patriots vs. Bears combos to pump you up for this prime-time tilt.
Here are my best NFL picks to combo on Oct. 22.
Best Patriots vs Bears combos
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Patriots vs Bears combo
Bears moneyline
A.J. Brown 70+ receivers
D’Andre Swift 3+ receptions
Prime-time pups are all the rage, so I’m avoiding laying the half-point hook on the field goal with the Chicago Bears and instead opting for the home team to win this one outright.
The Chicago defense has its holes, but it is aggressive and creates chaos, which in turn produces takeaways. New England Patriots quarterback Drake Maye has had his share of miscues already this season and is playing behind a patchwork offensive line.
A.J. Brown had a case of the butterfingers in his return from injury, dropping three of the 10 passes his way in Week 6. With the rust shaken off, Brown is the clear WR1 due to the Romeo Doubs injury, and he’s awesome versus man coverage, which Chicago runs a lot of.
D’Andre Swift hasn’t been able to gain traction as a rusher, so Ben Johnson is finding other ways to get the ball in his hands. He has eight catches on 10 targets in the past two games, and with the Pats bringing blitz, he’s a perfect check-down option for Caleb Williams.
Patriots vs Bears touchdown combo
Caleb Williams
A.J. Brown
Colston Loveland
Caleb Williams rushed for two touchdowns in Week 1 and can do damage with his legs against blitz-heavy defenses like New England’s.
Brown torched this Bears team for 132 yards and two touchdowns as an Eagle last season. With a negative game script expected, the Patriots will be forced to lean on the pass, and Brown should see his share of red-zone targets.
The Bears’ tight ends have drawn nine red-zone targets, resulting in five catches, but Colston Loveland has just one touchdown. New England’s pass coverage is struggling, with several members of its secondary on the injury report.
Patriots vs Bears milestone combo
D’Andre Swift 25+ receiving yards
A.J. Brown 100+ receiving yards
Drake Maye 40+ rushing yards
Swift has been more involved in the passing game over the past two weeks, recording 26 and 30 receiving yards in those outings.
Brown’s projections had a ceiling of 88 yards, and considering he’s one of the best WRs versus man coverage, getting to 100+ receiving yards isn’t a stretch.
The Bears bring blitz at the seventh-highest rate, putting pressure on Maye and forcing him to take off. He’s gone for 40+ rushing yards in two games in 2026. Chicago hasn’t faced many mobile QBs in the opening six weeks.
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