Anytime Touchdown Scorer 49ers vs Seahawks Prediction: TD Picks for NFC Divisional Round

With all eyes on Jaxon Smith-Njigba, Seattle wideout Cooper Kupp could emerge as a key factor inside the red zone.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Jan 16, 2026 • 15:24 ET • 4 min read
Cooper Kupp Seattle Seahawks NFL
Photo By - Reuters Connect. Seattle Seahawks wide receiver Cooper Kupp (10).

Christian McCaffrey and the San Francisco 49ers upset the Eagles last week, but now they head to Lumen Field on Saturday to face the No. 1-seed Seattle Seahawks.

While I expect C-Mac to add to his touchdown tally, Cooper Kupp also presents strong upside for a Seattle team that should have no trouble finding the end zone.

Here are my best free 49ers vs. Seahawks anytime touchdown picks for the NFC Divisional Round on January 17. 

For more NFL picks, make sure to check out our full 49ers vs. Seahawks predictions!

49ers anytime touchdown pick

Christian McCaffrey (-130 at FanDuel)

I don’t expect the San Francisco 49ers to generate much offense in this game, so it makes sense to go chalky with my anytime touchdown prop. If the Niners are going to score, there’s a strong chance it will come via Christian McCaffrey.

The Pro Bowl running back is a dual threat, capable of scoring on the ground and through the air. He’s recorded an incredible 98 red-zone touches this season (74 carries and 20 receptions), resulting in 17 total touchdowns.

C-Mac punched the ball into the end zone twice against Philadelphia last week and has scored in seven of his last eight games.

Enjoying Covers content? Add us as a preferred source on your Google account Add as a preferred source on Google

Seahawks anytime touchdown pick

Cooper Kupp (+310 at FanDuel)

Meanwhile, I could see the Seattle Seahawks putting up plenty of points against a San Francisco defense that ranks 30th in the league in success rate. That opens the door for several Seahawks playmakers to get in on the scoring action.

One of those is wide receiver Cooper Kupp. The veteran wideout was targeted 12 times in the red zone during the regular season, with eight of those coming in the final six weeks after Tory Horton suffered a season-ending injury.

Kupp is a reliable route-runner with sticky hands, and his experience is invaluable on a young team. That could make Sam Darnold look his way, especially with the Niners' defense focused on stopping Jaxon Smith-Njigba.

Bet on the NFL at FanDuel!

Make your NFL bets at FanDuel, America's No. 1 sportsbook! Sign up now and by placing $5 on your first bet, you could win $300 in bonus bets if your wager is a winner!

*Eligible U.S. locations only

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo