Notre Dame vs Boston College Prediction, Picks & Odds for November 1 — College Football Week 10

Farmer's prediction: Irish defense stifles Eagles in Holy War rivalry.

Douglas Farmer - Betting Analyst at Covers
Douglas Farmer • Betting Analyst
Oct 30, 2025 • 19:58 ET • 4 min read

NCAAF

Match starts: 38 hrs
BC
49 %
ND
51 %
EXPERT PICK - PROP
Boston College u13.5  (-110) Boston College u13.5 (-110)
Read Analysis
Adon Shuler Notre Dame Fighting Irish NCAAF
Photo By - Imagn Images. Notre Dame safety Adon Shuler (8) runs onto the field.

Some Boston College Eagles fans may try to convince you this is a rivalry game, but no Notre Dame Fighting Irish fans treat it with the same intensity a true rivalry deserves.

Rather, the biggest question for the Irish this weekend is just how many points they can win by to best bolster their College Football Playoff résumé.

My Notre Dame vs. Boston College predictions see the best path to an Irish blowout coming via their defense.

Read more in my college football picks for Saturday, November 1.

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Notre Dame vs Boston College prediction

Notre Dame vs Boston College best bet: Boston College team total Under 13.5 (-110)

Notre Dame’s defense began the season in rather ugly fashion, most notably giving up 41 points to Texas A&M and then 30 to Purdue. 

Since then, the Irish held Arkansas, Boise State, and North Carolina State all below 14 points before giving up 24 to USC. Those four opponents all fell short of their team totals by an average of 10.25 points.

Worse yet for Boston College, all four of those opponents have genuinely decent passing offenses. The worst among them is Arkansas’s, ranking No. 48 in the country in expected points added (EPA) per dropback, according to CFB-graphs.com. All four programs also pass the ball more often than expected for an average team in a given game state, with Boise State the most conservative at 1.2% above expectation, and the other three all at 3.1% or higher.

USC managed to put forth an about-average passing performance against the Irish, but the other three all set their offenses back with each dropback, NC State faring the worst at -0.402 EPA per dropback.

Enter Boston College, throwing the ball more often than any of these at 5.0% more often than expected, but doing so abysmally, ranking No. 125 in the country in EPA per dropback.

Notre Dame’s aggressive secondary should feast on the Eagles. Add in how poorly Boston College finishes quality drives — ranking No. 118 in the country at 2.68 points per quality drive — and the Eagles very well might not score a touchdown at all.

Notre Dame vs Boston College same-game parlay

Notre Dame needs to continue running up scores in order to impress the Playoff selection committee, and beating Boston College by 30+ will certainly fit that need. 

Receiver Will Pauling has caught a touchdown in four straight games, in part because slot counterpart Jaden Greathouse has missed three straight games. Greathouse has been ruled out for at least one more week with a hamstring injury.

Notre Dame vs Boston College SGP

  • Boston College team total Under 13.5
  • Notre Dame -28.5
  • Will Pauling anytime touchdown

Our deep-ball SGP: Carr Show

Notre Dame quarterback CJ Carr has thrown at least two touchdown passes in every Irish blowout this season, including four straight games before a mildly more competitive win against USC two weeks ago.

Grayson James has thrown for five touchdowns over his last two starts, but he’ll be lucky to get one against this Irish secondary.

Notre Dame vs Boston College SGP

  • Boston College team total Under 13.5
  • Notre Dame -28.5
  • Will Pauling anytime touchdown
  • CJ Carr Over 1.5 touchdown passes
  • Grayson Games Under 0.5 touchdown passes

Notre Dame vs Boston College odds

  • Spread: Notre Dame -28.5 (-110) | Boston College +28.5 (-110)
  • Moneyline: Notre Dame -7000 | Boston College +2000
  • Over/Under: Over 56.5 (-110) | Under 56.5 (-110)

Notre Dame vs Boston College trend to know

Boston College has gone just 2-5 against the spread vs. FBS opponents this season. Find more college football betting trends for Notre Dame vs Boston College.

How to watch Notre Dame vs Boston College

Location Alumni Stadium, Chestnut Hill, MA
Date Saturday, November 1, 2025
Kickoff 3:30 p.m. ET
TV ESPN

Notre Dame vs Boston College latest injuries

Notre Dame vs Boston College weather

Monitor gametime conditions with our College football weather info.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Douglas Farmer
Betting Analyst

Douglas Farmer spends his days thinking about college football and his nights thinking about the NBA. His betting habits and coverage follow that same pattern. He covered Notre Dame football for various outlets from 2008 to 2024, most notably spending eight seasons as NBC Sports’ beat writer on the Irish. That was also when his gambling focus took off. Knowing there were veteran beat writers with three decades more experience than he had, Douglas found his niche by best recognizing Notre Dame’s standing in each year’s national landscape, a complex tapestry most easily understood and remembered via betting odds.

In 2021, that interest created a freelance opportunity with Covers, a role that eventually led to Douglas joining the company full-time in 2023. In the fall, Douglas will place five or six dozen bets each week, a disproportionate amount via BetRivers because the operator tends to have lines slightly different than the rest of the market. The same can be said of Circa Sports’ futures markets.

While Douglas is an avid NBA fan and covers the league throughout the year, the vast majority of his bets are on college football, because that is the biggest key to sports betting: Know what you do not know.

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