Oregon faces a tough test in traveling to Kinnick Stadium to take on Iowa, highlighting Week 11's afternoon slate, along with an SEC showdown between No. 3 Texas A&M and No. 19 Missouri.
We've got a best bet for each of those games, plus a few other matchups in the late-afternoon time slot — see below for our college football picks and analysis.
College football best bets for Week 11 afternoon games
| Game | Time (ET) Network |
Best bet |
|---|---|---|
 vs  |
3:30 | CBS | Moulton o54.5 rush -114 |
 vs  |
3:30 | ABC | Over 47.5 -110 |
 vs  |
3:30 | ESPN | Under 45.5 -110 |
 vs  |
3:30 | FOX | -6.5 -122 |
 vs  |
3:30 | SECN | -6.5 -110 |
 vs  |
4:30 | BTN | -11.5 -106 |
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Oregon vs Iowa best bet
Kamari Moulton Over 54.5 rushing yards (-114 at FanDuel)
Oregon’s defense is much better against the pass (eighth in EPA per pass allowed) than the run (80th). It’s a comical stylistic clash in because the Hawkeyes are generally content to keep the ball on the ground. Moulton has seen steady volume, with 14+ carries in five consecutive games, and has responded with at least 68 rushing yards in each game.
See our full analysis and Ducks/Hawkeyes SGP in our Oregon vs. Iowa predictions.
Texas A&M vs Missouri best bet
Over 47.5 (-110 at FanDuel)
It may feel like Mizzou is in trouble offensively following QB Beau Pribula's ankle injury, suffered two weeks ago against Vanderbilt. However, head coach Eli Drinkwitz has had an extra week of practice with backup Matt Zollers, who looked impressive in relief. This total is overcompensating for the loss of Pribula; Texas A&M will continue to roll, and Zollers will be better than expected.
See our full analysis and Aggies/Tigers SGP in our Texas A&M vs. Missouri predictions.
Syracuse vs Miami best bet
Under 45.5 (-110 at FanDuel)
Syracuse is a complete mess on offense since losing starting QB Steve Angeli, failing to score more than 18 points in any game and averaging just 12 ppg in that span. Miami has also struggled, having been held to 28 points or less in four of its last five games, while also dealing with key injuries as WR CJ Daniels and RB Mark Fletcher Jr. could both sit out.
See our full analysis and Orange/Hurricanes SGP in our Syracuse vs. Miami predictions.
Iowa State vs TCU best bet
TCU -6.5 (-122 at FanDuel)
TCU’s offense is much more explosive than Iowa State, and the Cyclones' defense has really fallen apart over their last four games. ISU is 0-3 against the spread on the road, while the Horned Frogs are 3-1 ATS at home. TCU needs this game badly, and they will play like it against a struggling defense.
See our full analysis and Cyclones/Horned Frogs SGP in our Iowa State vs. TCU predictions.
Auburn vs Vanderbilt best bet
Vanderbilt -6.5 (-110 at FanDuel)
Vanderbilt owns a Top-10 offensive profile; it sustains drives at an elite rate and is great through the air (fifth nationally in pass success and sixth in EPA per dropback). That directly attacks Auburn’s weakest unit: Pass defense. The Tigers rank in the Bottom 40th percentile of college football against the pass.
See our full analysis and Tigers/Commodores SGP in our Auburn vs. Vanderbilt predictions.
Washington vs Wisconsin best bet
Washington -11.5 (-106 at FanDuel)
Wisconsin followed up a respectable showing at Oregon with an idle week, and now it seems the market has forgotten that things can always get worse. Before the Badgers scored a whopping seven points in the Pacific Northwest, they had gone more than 14 quarters without finding the end zone — one touchdown when trailing by 21 points should not erase those miseries from our memories.
See full analysis, and more of Douglas' best bets for Week 11, in his college football predictions for Week 11.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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