It’s a Southwest Division showdown tonight at the FedExForum as the San Antonio Spurs visit the Memphis Grizzlies.
With Victor Wembanyama questionable and De’Aaron Fox playing well right now, my Spurs vs. Grizzlies predictions and NBA picks are eyeing the guard to torch Memphis this evening.
Spurs vs Grizzlies prediction
Spurs vs Grizzlies best bet: De'Aaron Fox Over 22.5 points (-110)
De'Aaron Fox missed the start of the season due to injury, but he’s now healthy and thriving. The veteran is playing a key part for the San Antonio Spurs, averaging 21.7 points, 5.8 assists, and 3.8 rebounds per night.
Wemby is still battling knee soreness, and he may not suit up against the Memphis Grizzlies. Even if he does, this bet still offers value. Fox has cashed the Over in points in three of his last five games, and he already dominated the Grizzlies last month, balling out for 29.
The Kentucky product is also playing better on the road, averaging 23.2 ppg compared to 20.1 at home. Against Southwest Division opponents, Fox is averaging just north of 23 points per night. He’ll make his presence felt tonight.
Spurs vs Grizzlies same-game parlay
Jaren Jackson Jr. is averaging 18.4 points this season, and he’s cashed the Under in two of his last three outings. The Spurs held the big man to seven points in early December, and I expect another quiet night tonight.
Julian Champagnie is by no means a star, but he’s a crucial piece to the puzzle for the Spurs, averaging 10.8 points and 5.8 rebounds per contest. He’s had a couple of mammoth games lately, though, cashing the Over in two of his last three.
On Saturday, he scored 20 against the Trail Blazers. On New Year’s Eve, he also torched the Knicks for 36 points.
Spurs vs Grizzlies SGP
- De'Aaron Fox Over 22.5 points
- Jaren Jackson Jr. Under 19.5 points
- Julian Champagnie Over 12.5 points
Our "from downtown" SGP: No luck in Memphis
Cam Spencer isn’t shooting it well from deep at the moment, cashing the Under in triples made in four games in a row.
Spurs vs Grizzlies SGP
- De'Aaron Fox Over 22.5 points
- Jaren Jackson Jr. Under 19.5 points
- Julian Champagnie Over 12.5 points
- Cam Spencer Under 2.5 threes
Spurs vs Grizzlies odds
- Spread: Spurs -5.5 | Grizzlies +5.5
- Moneyline: Spurs -225 | Grizzlies +185
- Over/Under: Over 239.5 | Under 239.5
Spurs vs Grizzlies betting trend to know
The Spurs have cashed the moneyline in 14 of their last 21 away games for +24.10 units and a 61% ROI. Find more NBA betting trends for Spurs vs. Grizzlies.
How to watch Spurs vs Grizzlies
| Location | FedExForum, Memphis, TN |
| Date | Tuesday, January 6, 2026 |
| Tip-off | 8:00 p.m. ET |
| TV | FDSN-Southwest, FDSN-Memphis |
Spurs vs Grizzlies latest injuries
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