Yankees vs Athletics Prediction, Picks & Odds for Today’s MLB Game

The New York Yankees have a clear advantage in pitching today, which is why you should take them to win the first five innings.

Kenny Ducey - Contributor at Covers
Kenny Ducey • Betting Analyst
May 10, 2025 • 14:32 ET • 4 min read
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This article contains predictions for an old game!

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Carlos Rodon New York Yankees MLB
Photo By - Imagn Images. Rodon deals to the plate.

The New York Yankees are back on a roll with three wins in a row, and over that span, they’ve scored 26 runs to instill fear in opposing pitchers after a brief slump to begin the month.

Now, they’ll face a friendly fly-ball arm in one of their former farmhands, and my Yankees vs Athletics predictions will go over why they should have the upper hand in the pitching matchup.

Without further ado, let’s hand out some MLB picks for Saturday, May 10.

Yankees vs Athletics prediction

My Yankees vs Athletics best bet: Yankees F5 moneyline (-148 at FanDuel)

After a couple of tumultuous seasons with the New York Yankees, Carlos Rodon is finally pitching like Carlos Rodon again.

This man was one of the National League’s Top 5 arms as recently as two years ago, blending solid strikeout numbers with friendly numbers on contact, and in 2025, he will be taking yet another step forward.

Rodon has decided to mix in a sinker this season and throw the changeup more frequently, leading to a huge jump in ground ball rate. That’s not always the best strategy, but for a guy who struggled to a barrel rate over 11% the past two seasons, it’s refreshing to see.

The lefty’s heavy fly-ball approach led to plenty of home runs inside his hitter-friendly park, but now he can allow his dominant 30.3% strikeout rate to go to work even more for him. Pitching in Sacramento, Rodon will rest on his new profile to make it through.

JP Sears hasn’t learned quite the same lesson, though he’s pitched well enough to a 3.23 xERA thanks to very few walks and a fair bit of ground balls.

He’s brought his rate of contact on the ground up two points, though it hasn’t come up quite high enough, and that’s led to a 5.00 ERA in nine innings at home with two home runs.

The Athletics rank sixth in OPS against ground ball pitchers this season compared to 17th in the reverse split, but I have some doubts against Rodon, given they’re sporting just a .125 Isolated Power in the last two weeks.

The Yankees, meanwhile, are the fourth-best offense in those 14 days with an insane .246 ISO and low strikeout rate — and Sears may not stand a chance.

There’s little value to be found in the total here, so I think you want to take the better of the two starting pitchers for this kind of environment and bank on the Athletics’ lack of power.

Yankees vs Athletics same-game parlay (SGP)

Yankees F5 moneyline

Carlos Rodon Over 6.5 strikeouts

Paul Goldschmidt 2+ total bases

Rodon struck out just five San Diego Padres in his most recent start, but that’s a pretty impressive number given they’re one of the stingiest teams when it comes to striking out.

Prior to that, he’d gone for seven or more in all but one of his seven outings, and against an Athletics team which has stuck out in 22.5% of plate appearances vs. lefties, I think there’s a great chance he can do it again.

I also love Paul Goldschmidt here. Not only is he hitting over .300 against fly-ball arms this season, but he’s hitting .581 against southpaws in 37 plate appearances with a .450 ISO, with two multi-hit games in his last four.

Yankees vs Athletics odds

Yankees vs Athletics live odds

Yankees vs Athletics opening odds

  • Moneyline: New York -158 | Athletics +134
  • Run line: New York -1.5 (-105) | Athletics +1.5 (-114)
  • Over/Under: Over 10 | Under 10

Yankees vs Athletics trend

The New York Yankees have hit the first five innings (F5) moneyline in 21 of their last 38 games (+5.15 Units / 9% ROI)
 Find more MLB betting trends for Yankees vs. Athletics.

How to watch Yankees vs Athletics and game info

Location Sutter Health Park, West Sacramento, CA
Date Saturday, 5-10-2025
First pitch 4:05 p.m. ET
TV YES, NBCSCA
Yankees starting pitcher Carlos Rodon
(4-3, 2.96 ERA)
Athletics starting pitcher JP Sears
(4-2, 2.93 ERA)

Yankees vs Athletics latest injuries

Yankees vs Athletics weather

Not intended for use in MA.
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Kenny Ducey - Covers
Betting Analyst

Kenny Ducey has worked in sports media for more than 10 years and began his journey as a credentialed reporter with Fordham University's WFUV Sports before moving on to Sports Illustrated. There, he wrote about baseball, basketball, and tennis - twice covering the NBA Finals.

He's been in the betting space for seven years, and has established himself as a top expert in MLB and tennis handicapping with brands like Tennis Channel, NBC Sports, and DraftKings. He's also been a frequent guest on betting shows such as MLB's Bettor's Eye and Tennis Bets Live.

Kenny has a knack for identifying underappreciated pitchers and tennis players as moneyline underdogs and credits his unique data analysis and hours of watching sports as the biggest reasons for success through the years. His best advice to bettors? Watch the games, trust your eye, and always question the public narrative.

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