The Milwaukee Brewers and San Francisco Giants begin a four-game set tonight, with San Francisco looking to build on Sunday's offensive explosion.
However, my Giants vs. Brewers predictions are targeting Milwaukee's pitching to dominate the series opener amid their impressive form.
Find out more in my MLB picks for Monday, June 1.
Who will win Giants vs Brewers today: Brewers moneyline (-140)
The Milwaukee Brewers turn to Shane Drohan, who owns a 2.63 ERA this season, and posted a 2.05 FIP in May. While he's expected to work only a few innings, Milwaukee can comfortably turn the game over to one of baseball's best bullpens.
The Brewers' relievers have allowed just a 6% barrel rate this season and enter Monday's contest rested after only two bullpen arms were used on Sunday.
The San Francisco Giants don't have the same luxury. The Giants' bullpen owns a 4.88 xERA and 5.40 xFIP over the last week, while Landen Roupp rarely works deep into games.
Milwaukee's bullpen advantage should prove decisive. I'd play this pick up to -155.
COVERS INTEL: Milwaukee's bullpen has held opponents to a .245 BABIP over the last seven days.
Giants vs Brewers Over/Under pick: Under 7.5 (-120)
My secondary lean is the Under. While the Giants exploded for 19 runs against Colorado on Sunday, that outburst heavily inflates their recent offensive numbers.
Milwaukee's pitching situation remains strong, with Drohan expected to cover the opening innings before handing the ball over to one of baseball's best bullpens.
Roupp has also held his own recently, posting a 2.71 FIP across his last two starts. With Milwaukee's elite relief corps entering rested and San Francisco's offensive form potentially overstated, this game could be lower-scoring than expected.
I'll play this to -130.
- ML/RL bets: 20-14, +5.21 units
- Over/Under bets: 20-13, +3.40 units
Giants vs Brewers odds
- Moneyline: Giants +133 | Brewers -138
- Run line: Giants +1.5 (-163) | Brewers -1.5 (+156)
- Over/Under: Over 7.5 (+108) | Under 7.5 (-113)
Giants vs Brewers trend
The Giants have hit the team total Under in 26 of their last 40 away games (+10.15 Units / 22% ROI). Find more MLB betting trends for Giants vs. Brewers.
How to watch Giants vs Brewers and game info
| Location | American Family Field, Milwaukee, WI |
| Date | Monday, June 1, 2026 |
| First pitch | 7:40 p.m. ET |
| TV | FS1 |
| Giants starting pitcher | Landen Roupp (5-5, 3.30 ERA) |
| Brewers starting pitcher | Shane Drohan (2-1, 2.63 ERA) |
Giants vs Brewers latest injuries
Giants vs Brewers weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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