The Milwaukee Brewers host the Minnesota Twins in the second matchup of this three-game series at American Family Field. MLB odds list Minnesota as a -124 favorite, while the total sits at 7.5.
My Twins vs. Brewers prediction targets the total in this interleague matchup.
Read on for my MLB picks for Saturday, May 17.
Twins vs Brewers prediction
My Twins vs Brewers best bet: Under 7.5 (-110 at FanDuel)
The Minnesota Twins hands the ball to right-hander Pablo López, and he should serve as a good candidate to back. Through seven starts this season, López is 3-2 with a 2.77 ERA and 0.97 WHIP.
His underlying metrics are equally impressive. The right-hander ranks in the top third of the league in expected ERA (xERA), expected batting average (xBA), average exit velocity and hard-hit rate.
He has particularly displayed excellent command, ranking in the 80th percentile in strikeout rate and 91st percentile in walk rate.
Following López is one of the best bullpens in baseball. Entering this matchup, the Twins’ relief staff ranks fourth in ERA, second in fielding independent pitching (FIP), first in expected FIP (xFIP) and first in wins above replacement (WAR).
Meanwhile, right-hander Tobias Myers takes the mound for the Milwaukee Brewers. Through five appearances, Myers is 1-0 with a 3.86 ERA.
Analytically, he’s even stronger. Myers sports a 3.82 xERA and .239 xBA, two metrics that reflect his outstanding 1.9% barrel rate.
Twins vs Brewers same-game parlay (SGP)
Under 7.5
Pablo Lopez over 5.5 strikeouts
Twins moneyline
Sticking with the theme of a pitching duel, López is worth backing in the prop market. He ranks in the 61st percentile in whiff rate, 68th percentile in chase rate and 80th percentile in strikeout rate.
López has recorded six or more strikeouts in each of his past five starts.
Furthermore, if we are backing López to produce a strong performance, then there is an increased probability of Minnesota winning this game. The Twins outrank Milwaukee in batting average, slugging percentage and OPS.
Learn how to bet a same-game parlay with these helpful tips and strategies.
Twins vs Brewers odds
Twins vs Brewers live odds
Twins vs Brewers opening odds
- Moneyline: Minnesota -124 | Milwaukee +106
- Run line: Minnesota -1.5 (+136) | Milwaukee +1.5 (-164)
- Over/Under: Over 7.5 (-110) | Under 7.5 (-110)
Twins vs Brewers trend
There have been seven or fewer total runs scored in six of Milwaukee’s past seven games. Find more MLB betting trends for Twins vs. Brewers.
How to watch Twins vs Brewers and game info
| Location | American Family Field, Milwaukee, Wisconsin |
| Date | Saturday, 5-17-2025 |
| First pitch | 7:15 p.m. ET |
| TV | FOX |
| Twins starting pitcher | Pablo Lopez (3-2, 2.77 ERA) |
| Brewers starting pitcher | Tobias Myers (1-0, 3.86 ERA) |
Twins vs Brewers latest injuries
Twins vs Brewers weather
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