The Kansas City Royals have struggled miserably on the road this season, winning just 10 of 31 away games.
My Royals vs. Twins predictions and MLB picks see another loss in the cards on Friday, June 5 in Minnesota.
Who will win Royals vs Twins today: Twins moneyline (-115)
The Minnesota Twins are in good form offensively, ranking Top 12 in batting average, OPS, and wOBA against right-handed pitching over the last three weeks.
Their success should continue against Michael Wacha. He has faced six opponents that rank Top 20 in both average and ISO vs. righties and struggled in such matchups. He posted a 5.44 ERA and allowed three runs or more in four of the six starts.
The Kansas City Royals rank 28th in wOBA against righties on the road and will struggle to keep up. Play the Twins to -125.

Royals vs Twins Over/Under pick: Over 8.5 (+100)
Wacha has allowed 19 runs over his last four starts against teams sitting Top 20 in average and ISO against righties.
The Twins are in good form at the plate and have scored 4.72 runs per game in Minnesota this season. They should cause problems for Wacha and the subpar bullpen behind him.
Zebby Matthews has struggled to keep the ball on the ground, posting a fly-ball rate just under 50%. That’s a real issue given a high 16.1% HR/FB.
Expect the offenses to shine tonight. I'd play this to -110.
- ML/RL bets: 23-16, +0.92 units
- Over/Under bets: 19-19-2, -2.71 units
Royals vs Twins odds
- Moneyline: Royals -105 | Twins -115
- Run line: Royals -1.5 (+160) | Twins +1.5 (-190)
- Over/Under: Over 8 (-120) | Under 8 (+100)
Royals vs Twins trend
The Twins have cashed the Over in 21 of their last 35 games for +10 units and a 26% ROI. Find more MLB betting trends for Royals vs. Twins.
How to watch Royals vs Twins and game info
| Location | Target Field, Minneapolis, MN |
| Date | Friday, June 5, 2026 |
| First pitch | 8:15 p.m. ET |
| TV | Apple TV |
| Royals starting pitcher | Michael Wacha (4-3, 3.23 ERA) |
| Twins starting pitcher | Zebby Matthews (1-3, 4.63 ERA) |
Royals vs Twins latest injuries
Royals vs Twins weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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