MLB Player Props & Best Bets for Today, May 21

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst 7+ years betting experience
Updated: May 21, 2026 , 11:15 AM ET • 4 min read

Vladimir Guerrero Jr. keeps dominating Carlos Rodon.

Vladimir Guerrero Jr. Toronto Blue Jays MLB
Photo By - Reuters Connect. Toronto Blue Jays first baseman Vladimir Guerrero Jr. (27) hits an RBI sacrifice fly during the seventh inning against the New York Yankees

Today's slate features just seven games, but I've still found value in my MLB player props

I'm focusing on strong showings from Spencer Strider, Ronald Acuna Jr., and Vladimir Guerrero Jr. 

Read more in my MLB picks for Thursday, May 21. 

Best MLB player props today

Player  Pick Odds
Braves Spencer Strider Over 5.5 strikeouts -133
Braves Ronald Acuna Jr. Over 0.5 runs -106
Blue Jays Vladimir Guerrero Jr.  Over 0.5 RBI +185
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Spencer Strider Over 5.5 strikeouts (-133)

Spencer Strider only made his season debut at the beginning of this month, but he's been lights out. The right-hander owns a 2.45 ERA through three starts, and he's struck out 18 hitters in 14 2/3 innings of work. While Strider finished with just four Ks last time out, he cashed the Over in his two other appearances, and both were on the road. 

The Miami Marlins are 12th in team strikeouts, and they're averaging 9.67 punchouts over their previous three contests. Strider hasn't faced many of these Marlins hitters before, but his swing-and-miss stuff is evident right now. He'll rack up the Ks in the series finale here. 

  • Time: 6:40 p.m. ET
  • Where to watch: BravesVision, Marlins.TV

Ronald Acuna Jr. Over 0.5 runs (-106)

Ronald Acuna Jr. just returned from injury, and he's made an immediate impact for the Atlanta Braves. The slugger has four runs across his last two games, and he's hit the Over in runs scored in four straight. Acuna had two walks and a hit in the series opener against the Fish, and he registered another base knock on Wednesday. 

The Venezuelan will be licking his chops ahead of tonight's matchup, too. He'll face Sandy Alcantara, against whom he's hitting .342 (13-for-38) with four doubles, a triple, two home runs, and two RBI. He's also drawn eight walks vs. Alcantara, and the Braves are hitting .270 with RISP. 

  • Time: 6:40 p.m. ET
  • Where to watch: Braves.Vision, Marlins.TV

Vladimir Guerrero Jr. Over 0.5 RBI (+187)

The Toronto Blue Jays take on the New York Yankees again tonight, and Vladimir Guerrero Jr. will be biting at the bit to step up to the plate. Carlos Rodon takes the hill, and Guerrero is 11-for-18 lifetime against the lefty with seven RBI. He's driven in a run in each of the first two games of this series as well. 

The slugger's last three RBI have all been on the road, where he's notched 13 of his 22 RBIs on the year. Rodon has had serious trouble getting Guerrero out, and it's common knowledge that the 27-year-old typically swings it well against the Bronx Bombers overall. 

  • Time: 7:05 p.m. ET
  • Where to watch: Sportsnet, YES
Quinn Allen's 2026 Transparency Record
  • Prop picks: 34-62, +3.65 units

Odds are correct at the time of publishing and are subject to change.
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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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