Padres vs Phillies Prediction, Picks & Best Bets for Tonight’s MLB Game

Zack Wheeler will be on the mound for Philly tonight, and our Padres vs. Phillies predictions think that gives the home team a huge edge.

Neil Parker - Analyst at Covers.com
Neil Parker • Betting Analyst
Jun 30, 2025 • 15:25 ET • 4 min read

MLB

Match starts: 2 hrs
PHI
78 %
SD
23 %
EXPERT PICK - RUN LINE
Philadelphia -1.5 (-110) Philadelphia -1.5 (-110)
Read Analysis
Zack Wheeler Philadelphia Phillies MLB
Photo By - Imagn Images. Zack Wheeler on the mound against the Blue Jays in a recent start.

A pair of the best teams in the National League hit the field at Citizens Bank Park, with the Philadelphia Phillies hosting the San Diego Padres on Monday, June 30.

Philly has ace Zach Wheeler hitting the bump, while San Diego will counter with Matt Waldron making his first start of the year. My Padres vs. Phillies predictions and top MLB picks are calling for Wheeler to lead the way to a convincing win in the City of Brotherly Love.

Padres vs Phillies prediction

My Padres vs Phillies best bet: Phillies -1.5 (-115 at Caesars)

Caesars QuickPick: Our Padres vs Phillies same-game parlay (SGP)

Phillies -1.5

Kyle Schwarber Over 1.5 hits + runs + RBI

Fernando Tatis Jr. Over 1.5 total bases

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Padres vs Phillies odds

Padres vs Phillies live odds

Padres vs Phillies opening odds

  • Moneyline: San Diego +180 | Philadelphia -220
  • Run line: San Diego +1.5 (-110) | Philadelphia -1.5 (-110)
  • Over/Under: Over 9 | Under 9

Odds courtesy of Caesars.

Padres vs Phillies trend

The Phillies have cashed the moneyline in 36 of their last 58 games (+7.85 units / 9% ROI). Find more MLB betting trends for Padres vs. Phillies.

How to watch Padres vs Phillies and game info

Location Citizens Bank Park, Philadelphia, PA
Date Monday, 6-30-2025
First pitch 6:35 p.m. ET
TV MLB Network
Padres starting pitcher Matt Waldron
(0-0, 0.00 ERA)
Phillies starting pitcher Zack Wheeler
(7-3, 2.45 ERA)

Padres vs Phillies latest injuries

Padres vs Phillies weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Neil Parker - Covers
Betting Analyst

Neil Parker is, first and foremost, a sports fan. A huge supporter of the Cowboys, Cubs, and Maple Leafs, he has managed to parlay his passion into writing gigs with Sportsbook Review, USA TODAY, theScore, DraftKings Playbook, and RotoWire, among many others. He also co-hosted the Daily Fantasy Edge podcast and can now be seen offering expert golf and hockey advice on Covers’ Before you Bet broadcast.

Neil takes a numbers-based approach to his handicapping and complements his in-depth statistical analysis with a keen eye on the markets to provide the best available odds. He loves to lean on his rolodex of idioms to offset his inner nerd. When it comes to wagering, he throws down on anything that catches his eye at bet365, Betway and BetVictor. He also keeps a close eye on CoolBet because the polar bear brand often has outlier NHL and NFL moneyline prices.

Neil graduated with honors from St. Thomas University in 2007 before completing his BEd at Acadia University in 2010. After teaching a myriad of courses and subjects, he found a groove delivering fun lessons to exceptional learners in non-traditional classroom environments. If his decade-plus teaching run taught him anything about sports betting, it’s to stay the course and use the summer – or offseason – to refresh and prepare to be better in the year to come.

Neil’s top pieces of advice for recreational bettors are to stay within your means and to remember sportsbooks aren’t bank accounts. Don’t be afraid to pull those winnings and treat yourself to a lifetime experience courtesy of a big win.

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