Padres vs Diamondbacks Prediction, Picks & Odds — Tuesday, August 5

Caley's prediction: Caroll leads the charge vs. Padres.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Aug 5, 2025 • 15:12 ET • 4 min read

MLB

Match starts: 3 hrs
AZ
54 %
SD
46 %
EXPERT PICK - PROP
Corbin Carroll o2.5  Hits, Runs, and RBIs (+125) Corbin Carroll o2.5 Hits, Runs, and RBIs (+125)
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Arizona Diamondbacks right fielder Corbin Carroll (7) hits a single against Detroit Tigers.
Photo By - Imagn Images. Arizona Diamondbacks right fielder Corbin Carroll (7) hits a single against Detroit Tigers.

The San Diego Padres went all-in at the trade deadline, but if they want to achieve their goals of winning a World Series, they’ll need the best version of Yu Darvish.

The veteran right-hander is coming off his best start of the season, but the Arizona Diamondbacks will provide an interesting test. And one D-back in particular has been a thorn in Darvish’s side.

My Padres vs. Diamondbacks predictions are highlighted by a player prop and more MLB picks for this National League West showdown with first pitch in Phoenix scheduled for 9:40 pm ET on Tuesday, August 5.

Padres vs Diamondbacks prediction

My Padres vs Diamondbacks best bet: Corbin Carroll Over 2.5 hits, runs, and RBI (+125 at BetMGM)

The San Diego Padres made some of the boldest moves at the trade deadline, but they still need their starting pitching to step up if they hope to compete with the other contenders in the National League.

That includes veteran Yu Darvish. The veteran right-hander has missed the majority of the season with inflammation in his throwing elbow and will be making just his sixth start since returning to the Padres’ rotation at the beginning of July.

It’s taken Darvish a while to knock the rust off, but he's coming off his best performance of the season, shutting out the Mets over seven innings on just two hits. However, a matchup with Corbin Carroll and the Arizona Diamondbacks could indicate a slight regression.

That’s because Ketel Marte, Alek Thomas, and most specifically, Corbin Carroll have great numbers against the Padres’ right-hander.

But let’s focus on Carroll. The two-time All-Star is a ridiculous 8-for-15 with two doubles and two dingers in his career vs. Darvish. That’s good for a .359 expected batting average and a .689 expected slugging.

Carroll has also been in a groove in the second half. He’s hitting .293 with a .907 OPS over the last 15 games. Carroll has also scored nine runs and driven in eight more. 

That has me looking at his Hits, Runs, and RBIs prop, which is set at 2.5 for this matchup vs. Darvish. But it’s a number he’s gone Over three times in his last six games. And he totaled five when he last faced Darvish back on July 7. I love taking this shot at plus money.

Padres vs Diamondbacks same-game parlay (SGP)

Corbin Carroll Over 2.5 H/R/R

Ryne Nelson Under 16.5 outs

Xander Bogaerts Over 1.5 H/R/R

Countering Darvish is Ryne Nelson. The 27-year-old right-hander has had an up-and-down season and enters this game ranked in the 43rd percentile in expected ERA. Like Darvish, a few Padres in particular have given him real problems in the past.

Nelson has also been a permanent starter for the D-backs for just the last two months. He averages 85.2 pitches per start, and with a tough matchup with the Padres, we’re putting Under 16.5 outs for Nelson in this same-game parlay. A number he’s stayed Under in five of his last 10 starts, including a June 13 meeting against the Padres.

One of his toughest outs has been Xander Bogaerts. The Padres infielder is 4-for-11 with two home runs in his career vs. Nelson. That’s good for a .370 expected batting average and a .935 expected slugging.

Let’s add Over 1.5 H/R/R for Bogaerts to this SGP as well. 

Padres vs Diamondbacks odds

Padres vs Diamondbacks live odds

Padres vs Diamondbacks opening odds

  • Moneyline: Padres -135 | Diamondbacks +115
  • Run line: Padres -1.5 (+115) | Diamondbacks +1.5 (-135)
  • Over/Under: Over 9.0 | Under 9.0

Padres vs Diamondbacks trend

The Diamondbacks have hit the Game Total Under in 10 of their last 14 games for +8.90 Units and a 58% ROI. Find more MLB betting trends for Padres vs. Diamondbacks.

How to watch Padres vs Diamondbacks and game info

Location Chase Field, Phoenix, AZ
Date Tuesday, 8-5-2025
First pitch 9:40 p.m. ET
TV SDPA, ARID
Padres starting pitcher Yu Darvish
(1-3, 6.46 ERA)
Diamondbacks starting pitcher Ryne Nelson
(6-3, 3.20 ERA)

Padres vs Diamondbacks latest injuries

Padres vs Diamondbacks weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Andrew Caley
Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew "Taco" Caley wanted to do was write about sports, something he's been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS. These days Andrew's betting expertise is focused on his favorite teams; the Toronto Blue Jays and Toronto Raptors. He's also an avid college football fan and bettor. He can't be friends with you if you don't appreciate a Service Academy Under. The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It's not an interesting story. Seriously.

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