MLB Home Run Predictions Today: Best HR Prop Bets, Picks, Parlay & Odds for Thursday, May 21

Josh Inglis - Betting Analyst at Covers.com
Josh Inglis • Betting Analyst 13+ years betting experience
Updated: May 21, 2026 , 09:28 AM ET • 4 min read

After a day of rest, Corbin Carroll will step back in the box against the Rockies, launching one over the fences in the process.

Corbin Carroll Arizona Diamondbacks MLB
Photo By - Reuters Connect. Arizona Diamondbacks right fielder Corbin Carroll (7) slides into third base with a triple against the San Francisco Giants

It's a small slate Thursday, and things have been at their coldest around here of late. It's time to ask sweet Baby Jesus to bless these four-baggers and MLB player props. I don't always look for help, but today it's needed, and one game is getting a lot of attention.

The Colorado Rockies just saw lefty Eduardo Rodriguez, and the familiarity factor usually isn't priced in, while the Diamondbacks might get to tee off on a bunch of Colorado bullpen arms, and with how that stable of relievers has played over the last two weeks, the home side is going deep today. 

These are my favorite home run predictions for Thursday, May 21. 

Best MLB home run props today

Player to hit a HR Odds
Rockies Hunter Goodman +447
Diamondbacks Corbin Carroll +445
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Home run pick: Hunter Goodman (+447)

Hunter Goodman is just 1-for-13 in his career against Arizona Diamondbacks lefty Eduardo Rodríguez, but at this price, there is still plenty of home-run upside today.

First, it’s a small slate, but Goodman just saw E-Rod in his last start and did rope a 101-mph single off him. The Colorado Rockies also put nine balls in play at 95+ mph against the lefty in that series. Goodman posted a .969 OPS during it as well, including a homer off Merrill Kelly. The right-handed bat also owns the fastest swing on the team over the last two weeks at 75 mph.

The familiarity factor usually isn’t priced in, which gives this HR prop more expected value with a fair price around +380. The lefty starter has also pitched above both his career fly-ball and HR/FB rates, so some long-ball regression could finally be on the way.

With colder weather rolling in and pitcher-friendly winds showing up around the league, a controlled hitting environment may be the best place to hunt dingers on a small-slate Thursday.

  • Time: 9:40 p.m. ET
  • Where to watch: DBACKS.TV, Rockies.TV

Home run pick: Corbin Carroll (+445)

The Diamondbacks have a great hitting matchup today as the Rockies are rolling with call-up Zach Agnos, who hasn’t started a game this year and will hand things off early to a Colorado bullpen that owns the second-worst ERA over the last two weeks and ranks 28th in HR/FB rate over that stretch.

Corbin Carroll got the day off yesterday, but before that, he had ripped triples in back-to-back games and, three games ago, launched a pair of home runs against the Rockies and this bullpen.

It’s also nice to get a Top-10 bat sitting right at +EV with a fair price around +360. Over the last two weeks, Carroll ranks eighth in BlastContact, third in slugging, and second in ISO. On this small slate, he projects as the third-most likely player to go deep behind only Aaron Judge and Mike Trout.

  • Time: 9:40 p.m. ET
  • Where to watch: DBACKS.TV, Rockies.TV
Josh Inglis' 2026 Transparency Record
  • HR picks: 13-83, -15.94 units

Odds are correct at the time of publishing and are subject to change.
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Josh Inglis - Covers
Betting Analyst

Josh Inglis is a rising star in the sports betting content space, specializing in MLB, NHL, and NFL markets. Since joining Covers in 2019, Josh has focused his betting expertise on player props and derivative markets, finding them easier for beating the closing line compared to sides and totals. His engaging analysis and content have been showcased on major networks such as TSN, VSiN, BetMGM Network, and NBC. Josh is a prolific bettor, tracking over 2,500 bets annually and he consistently shares his results through monthly transparency reports. At Covers, he is renowned for his MLB release shows and NHL Puck Props, which are integral parts of the site's live content lineup.

Before his tenure at Covers, Josh spent a decade teaching while pursuing sports media on the side. He has also contributed to live global senior-level broadcasts for the WBSC.

Josh advocates for sports bettors to bet early, emphasizing the importance of securing better numbers by beating the public to the market. He also advises having multiple sportsbook accounts to ensure access to the best possible odds.

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