Giants vs Dodgers Picks and Predictions: Life (and Buehler's Fastball) Moves Pretty Fast

The Giants are the first team to 60 wins, after taking two of the first three on the road from the Dodgers. But L.A. has its ace on the mound tonight, so we're expecting the home team to deliver as a big MLB betting favorite.

Jul 22, 2021 • 14:24 ET • 4 min read
Walker Buehler Los Angeles Dodgers MLB
Photo By - USA TODAY Sports

The San Francisco Giants are the first team in the MLB to reach 60 wins this season and they did it after beating the Los Angeles Dodgers for the second time in three games, extending their lead in the National League West to two games.

Can the Giants continue to be David, and win their third game in this series as underdogs, or will Walker Buehler prove too much as the Dodgers try to earn the split? 

Find out who has the MLB betting edge in our free baseball picks and predictions for Giants vs. Dodgers on Wednesday, July 22.

Giants vs Dodgers game info

Location: Dodger Stadium, Los Angeles, CA
Date: Thursday, July 22, 2021
Time: 10:10 p.m. ET
TV: NBCS BA, SportsNet LA

Giants vs Dodgers odds

Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.

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MLB sharp money and line movement report

By Patrick Everson

TwinSpires Sportsbook opened the Dodgers -165 and spent some time at -172 on the way to -177, where the moneyline sits at 6:45 p.m. ET. But the betting splits bely the movement, with the Giants taking 63 percent of bets and 68 percent of money. "San Francisco is a trendy 'dog tonight. It's a rare spot where we'll need the Dodgers," TwinSpires trading analyst Zachary Lucas said. The total is stable at 7.5, with 65 percent of tickets/55 percent of cash on the Over.

Check out the full line movement for this game

Giants vs Dodgers betting preview

Starting pitchers

Anthony DeSclafani (10-4, 2.78 ERA): Talk about a breakout season! DeSclafani is having the best year of his career, as the right-hander has a 2.78 ERA, a 0.99 WHIP, and is limiting opponents to a .201 batting average. All career bests for the 31-year-old in his first season pitching in the Bay.

Walker Buehler (10-1, 2.37 ERA): Buehler has been the Dodgers' best starter this season and hasn’t allowed more than three earned runs in a start since May 11. In that 12 start stretch, he is pitching to a 1.75 ERA and is limiting opponents to a .172 batting average.

Weather

Be sure to monitor the gametime conditions with our MLB weather info.

Key injuries

Giants: Brandon Crawford SS (Out), Evan Longoria 3B (Out), Tommy La Stella 2B (Out), Brandon Belt 1B (Out), Reyes Moronta RP (Out).
Dodgers: Mookie Betts RF (Questionable), Justin Turner 3B (Questionable), Corey Seager SS (Out), Jimmy Nelson RP (Out), Scott Alexander RP (Out), Gavin Lux 2B (Out),  Corey Knebel RP (Out).
Find our latest MLB injury reports.

Betting trend to know

The Under is 5-0 in Anthony DeSclafani's last five starts on the road. Find more MLB betting trends for Giants vs. Dodgers.

Moneyline pick

A night after a ninth-inning comeback by the Dodgers on Tuesday, San Francisco plated three runs in the top of the ninth last night on its way to a 4-2 victory. But L.A. is happy to hand the ball to Walker Buehler with a chance to even up the series between these NL West rivals.

As mentioned, Beuhler has been on quite the roll — and he has been outstanding at Dodger Stadium. The righty has a 2.31 ERA with an 0.96 WHIP and is limiting opponents to a .192 batting average in 11 starts at home this season. 

While DeSclafani has been arguably as good as Buehler this season, the potent Dodgers lineup has given him some problems. L.A. has lit up DeSclafani to the tune of a 10.95 ERA, 2.27 WHIP, and is hitting .352 with five dingers in three games against him this season.

With DeSclafani’s struggles against the Dodgers and Buehler’s recent dominance, it looks like it is worth backing the favorite at this price.

PREDICTION: Dodgers (-160)

Over/Under pick

The Over has been the slightly better bet when these two teams have met this season, going 7-5 in their 12 games, but with these two starters on the bump, we’re leaning the other way in this one — even with a low number of 7.5.

Yes, we said how DeSclafani has been thumped by the Dodgers this season but he was a little better in his most recent two starts against them, allowing five earned runs on 10 hits in 9 2-3 innings. The other thing is since he is backed up by an excellent bullpen, he will likely have a short leash if he gets in trouble. San Fran ranks third in bullpen ERA and first in WHIP.

Buehler, on the other hand, has allowed a single run on 12 hits in 19 2-3 innings in three starts against the Giants this season and is backed up by a bullpen that ranks 10th in ERA and sixth in opponent batting average. Bet this one to stay Under the number.

PREDICTION: Under 7.5 (-110)

Giants vs Dodgers betting card

  • Dodgers ML (-160)
  • Under 7.5 (-110)

Picks made on 7/22/2021 at 2:02 p.m. ET

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