San Diego Padres 3B Manny Machado's prowess against the Los Angeles Dodgers has been well documented.
My Dodgers vs. Padres predictions and MLB picks for Wednesday, June 11, expect another big game at the dish for the veteran infielder.
Dodgers vs Padres prediction
My Dodgers vs Padres best bet: Manny Machado Over 1.5 total bases (-110 at bet365)
Los Angeles Dodgers lefty Justin Wrobleski hasn’t fared well in his previous two away starts this season, and he likely won’t today against the big-hitting San Diego Padres.
Wrobleski has allowed 12 earned runs across 11 away frames, mostly because righties slash .324/.366/.432 against him.
That could mean a big day for Padres 3B Manny Machado. He’s crushing lefties (1.024 OPS) and slashes .324/.367/.647 with 33 hits and nine bombs across 102 lifetime at-bats against LA.
If Machado doesn’t get to Wrobleski, the Padres slugger can seal the deal against a leaky Dodgers bullpen yielding 52 earned runs with a 29th-best 4.24 xFIP across the last two weeks.
Machado is riding an eight-game hitting streak and has cleared 2+ total bases in six straight.
Dodgers vs Padres same-game parlay (SGP)
Manny Machado 2+ total bases
Randy Vasquez 3+ strikeouts
Padres moneyline
Randy Vasquez has quality starts in three of six at Petco and has recorded 3+ punchouts in six of seven starts. He should twirl three against a Dodgers lineup with 20 strikeouts in this series.
The Padres are 21-11 SU at Petco. They’ve scored 20 runs in this series with the much fresher bullpen. San Diego should get the win over a .500 Dodgers with an inconsistent starter and gassed bullpen.
Dodgers vs Padres odds
Dodgers vs Padres live odds
Dodgers vs Padres opening odds
- Moneyline: Los Angeles -140 | San Diego +120
- Run line: Los Angeles -1.5 (+110) | San Diego +1.5 (-130)
- Over/Under: Over 9.5 (+100) | Under 9.5 (-120)
Dodgers vs Padres trend
Manny Machado has cleared 2+ total bases in eight of his previous 10 games. Find more MLB betting trends for Dodgers vs. Padres.
How to watch Dodgers vs Padres and game info
| Location | PETCO Park, San Diego, CA |
| Date | Wednesday, 6-11-2025 |
| First pitch | 4:10 p.m. ET |
| TV | SNLA, SDPA |
| Dodgers starting pitcher | Jacob Wrobleski (1-2, 7.20 ERA) |
| Padres starting pitcher | Randy Vasquez (3-4, 3.70 ERA) |
Dodgers vs Padres latest injuries
Dodgers vs Padres weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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