Blue Jays vs Yankees Prediction, Odds & Home Run Pick for Today's MLB Game

Dustin Saracini -  - Betting Analyst at Covers.com
Dustin Saracini • Betting Analyst 14+ years betting experience
Updated: Aug 22, 2026 , 09:14 AM ET • 4 min read

Dylan Cease owns the Yankees, so our MLB expert will ride with him as a road underdog.

Dylan Cease Toronto Blue Jays MLB
Photo By - Reuters Connect. Dylan Cease of the Toronto Blue Jays.

It’s Dylan Cease bump day, so you know we have to back Toronto in our Blue Jays vs. Yankees predictions.

The Toronto Blue Jays visit the New York Yankees for Game 2 of their three-game series this afternoon at Yankee Stadium as slight -105 underdogs at BET99. They’ve shrunk their path to the Wild Card to just 1.5 games, and are looking for an eighth straight series win.

Let’s dive into my MLB picks for Saturday, Aug. 22, and win another best bet.

Blue Jays vs Yankees predictions

Blue Jays vs Yankees best bet: Blue Jays moneyline (-105)

Dylan Cease is likely going to win the AL Cy Young odds race for a reason — he’s pretty good at throwing baseballs. He’s especially good at throwing baseballs against the New York Yankees.

Across 126 plate appearances, New York owns just a .306 xwOBA, .232 xBA, and is striking out at a 28% clip.

The Toronto Blue Jays fare much better against Ryan Weathers, owning a .311 average and .469 xSLG over 66 at-bats.

Look for them to take Game 2 of the series with Cease on the mound.

Covers COVERS INTEL: Who's hotter than Alejandro Kirk right now? He just moved his hitting streak to nine games yesterday, and is 3-for-5 with a .330 xBA against Weathers.

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Blue Jays vs Yankees same-game parlay (SGP)

We’re riding Cease to go deep and record nine strikeouts after punching this lineup out at a 28% rate.

Charles McAdoo has also done his job since getting called up, and we’re taking a chance on him after going 2-for-3 in his initial meeting with Weathers. Let’s cash our third SGP this week.

Blue Jays vs Yankees SGP

  • Charles McAdoo 2+ H/R/RBI
  • Blue Jays moneyline
  • Dylan Cease 8+ Ks

Covers Alberta: Sports betting is now live!

Regulated Alberta sports betting has officially launched, allowing sportsbooks to operate under provincial oversight.

You can sign up and join BET99 — one of the best Alberta betting apps — now to get in on the Blue Jays action!

Blue Jays vs Yankees home run pick: George Springer (+575)

Let’s ride with the veteran George Springer here, who has two homers under his belt against Weathers in just eight at-bats.

At this price, you have to take a chance on him at one of the most hitter-friendly ballparks in the bigs.

2026 Transparency Record
  • Best bets: 5-5, +2.36 units 
  • SGPs:  2-8, -0.7 units
  • HR picks: 0-10, -2.3 units

Blue Jays vs Yankees odds

  • Moneyline: Toronto (-105) | New York (-115)
  • Run line: Toronto -1.5 (+170) | New York +1.5 (-210)
  • Over/Under: Over 7 (+100) | Under 7 (-120)

Blue Jays vs Yankees trend

The Blue Jays are 5-0 in Cease's last five starts as a road underdogs. Find more MLB betting trends for Blue Jays vs. Yankees.

How to watch Blue Jays vs Yankees and game info

Location Yankee Stadium, Bronx, NY
Date Saturday, August 22, 2026
First pitch 1:35 p.m. ET
TV YES, SportsNet
Blue Jays starting pitcher Dylan Cease
(7-5, 2.42 ERA)
Yankees starting pitcher Ryan Weathers
(5-7, 3.56 ERA)

Blue Jays vs Yankees latest injuries

Blue Jays vs Yankees weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Dustin Saracini
Betting Analyst

Dustin Saracini is a betting analyst at Covers with over 14 years of experience in the sports betting industry. Throughout his career, Dustin has hosted multiple betting shows- breaking down NBA, NFL, PGA, and MLB markets alongside top handicappers - and has appeared as a Super Bowl consultant for CNN. A disciplined daily bettor who extensively line-shops across FanDuel, DraftKings, BetMGM, and Caesars, his sharpest edges lie in MLB and the NFL (followed closely by the NHL and NBA). A self-proclaimed NRFI guru targeting his second straight +10u MLB season, Dustin holds a Broadcast Journalism degree from Western University (2014). For daily picks, market strategies, and insights, follow him on X (Twitter) @DustinSaracini.

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