The Saskatchewan Roughriders will look to jump out to a 2-0 start for the third consecutive season on Saturday night.
But they'll need to do it against the Calgary Stampeders, a team that's taken five of the last six matchups between them.
My Roughriders vs. Stampeders predictions and free CFL picks go against the grain by picking the road team, who now have the pieces to pick apart a good defense.
Roughriders vs Stampeders prediction
Roughriders vs Stampeders best bet: Roughriders -1.5 (-105)
The Grey Cup champions would love to beat the one team they never solved last season.
The Saskatchewan Roughriders revamped front seven held up last week and gets another test against Dedrick Mills, whose running kept QB Vernon Adams Jr. balanced in the Calgary Stampeders two wins last year.
Trevor Harris is coming off a 417-yard, three-touchdown performance against BC, and he'll have a healthier supporting cast this time.
Samuel Emilus and Kian Schaffer-Baker, both injured and unavailable in last year's losses to the Calgary Stampeders, are healthy, dynamic, and arguably the CFL's top receiving duo.
I'd lay up to -3 with Saskatchewan.

Roughriders vs Stampeders same-game parlay
With his receivers healthy, Trevor Harris has a higher-octane element to an offense that was middle of the pack in scoring last season (26.2 points per game).
That will matter against Calgary, who have held the Riders to less than 20 points in four of six matchups.
As I'm taking Saskatchewan to cover, it should be noted that the one time they did cover the spread in the last six against the Stamps, they hung a 37-29 win on them.
Calgary likely welcomes that style, as they're built for shootouts. The Stampeders have crossed the Over in seven of its last eight.
Roughriders vs Stampeders SGP
- Roughriders -1.5
- Over 51.5 points
Roughriders vs Stampeders odds
- Spread: Roughriders -1.5 | Stampeders +1.5
- Moneyline: Roughriders -125 | Stampeders -115
- Over/Under: Over 51 | Under 51
Roughriders vs Stampeders trend
The Roughriders have covered the spread in four of their last five games.
How to watch Roughriders vs Stampeders and game info
| Location | McMahon Stadium, Calgary, AB |
| Date | Saturday, June 20, 2026 |
| Kick-off | 7 p.m. ET |
| TV | TSN |
Roughriders vs Stampeders key injuries
Roughriders: FB Albert Awachie (out), WR Tommy Nield (out), OL Bryadon Noll (out), DB Kosi Onyeka (out), WR Shawn Bane (out).
Stampeders: WR Reggie Begelton (out), OL Bryce Bell (out), OL Aaron Crawford (out), LB Marquel Lee (out), DB Bentlee Sanders (knee), DL Charles Wiley (out).
Roughriders vs Stampeders weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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