Lions vs Roughriders Prediction, Picks & Odds for CFL Western Final

Ponnaiya's prediction: Backed by an elite rushing attack and defence, A.J. Ouellette & Co. will be Grey Cup-bound by the end of Saturday night.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Nov 7, 2025 • 15:01 ET • 4 min read

CFL

Match starts: 22 hrs
SSK
47 %
BC
53 %
EXPERT PICK - SPREAD
Saskatchewan -2.5 (-125) Saskatchewan -2.5 (-125)
Read Analysis
A.J. Ouellette Saskatchewan Roughriders CFL
Photo By - Imagn Images. Saskatchewan Roughriders running back A.J. Ouellette (45).

The Saskatchewan Roughriders welcome the BC Lions to Mosaic Stadium in the West Final on Saturday.

Saskatchewan finished the regular season with the best record in the league, and my Lions vs. Roughriders predictions are betting on them to win and cover at home.

Here are my best free CFL picks for this playoff clash on November 8, with kickoff at 6:30 p.m. ET.

Lions vs Roughriders prediction

My Lions vs Roughriders pick: Roughriders -2.5 (-125 at BET99)

The BC Lions were fortunate to escape the West Semi-Final on a walk-off field goal. They were outgained 476-298 by the Stampeders, but the Leos got huge plays on special teams, and some lucky bounces went their way as well.

Now they're on the road against a well-rested Saskatchewan Roughriders squad that's been the best team in the CFL all year. The Riders haven't played a meaningful game since October 10, which has allowed their banged-up receivers and defensive backs to get healthy.

Temperatures are expected to dip below freezing in Regina on Saturday. That plays right into the hands of the Riders, who have an elite rushing attack led by A.J. Ouellette, along with the league's best run defence.

Meanwhile, the Leos play their home games indoors and aren't as suited for cold-weather contests. They've struggled to defend the run, and star RB James Butler is questionable with an ankle injury. Even if he plays, he'll be less than 100%, which we saw last week when he was held to 25 yards on seven carries.

Both teams have explosive passing games, but the Riders have the superior stop unit, especially at linebacker and in the secondary. Expect them to lean on the ground game and defense to cover.

Lions vs Roughriders same-game parlay (SGP)

Roughriders -2.5

Over 53.5

The Lions lead the league in nearly every offensive category during the regular season thanks to MOP favorite Nathan Rourke. That said, their vulnerable defense has led to the Over going 11-2 in their last 13 games.

The Over also cashed in the first two meetings between these teams this year. Although they finished just below the total in Week 21, that was with Saskatchewan pulling Ouellette and QB Trevor Harris in the second quarter.

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Lions vs Roughriders odds

Lions vs Roughriders live odds

Lions vs Roughriders opening odds

  • Spread: BC +3.5 (-110) | Saskatchewan -3.5 (-110)
  • Moneyline: BC +140 | Saskatchewan -170
  • Over/Under: Over 53.5 (-110) | Under 53.5 (-110)

Lions vs Roughriders trend

The Roughriders are 5-0 ATS in the last five meetings between these West Division foes.

How to watch Lions vs Roughriders and game info

Location Mosaic Stadium, Regina, SK
Date Saturday, November 8, 2025
Kick-off 6:30 p.m. ET
TV TSN

Lions vs Roughriders key injuries

Lions: James Butler RB (Questionable), Dejon Allen RT (Out), Sione Teuhema DL (Out), Cristophe Beaulieu S (Out), Jalon Edwards-Cooper DB (Out).
Roughriders: KeeSean Johnson WR (Out), Shawn Bane Jr. WR (Out), Daniel Johnson OT (Out), Shane Ray DE (Out), Benny Sapp III DB (Out).

Lions vs Roughriders weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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