The Chicago Sky are seeking a 3-0 start to the WNBA season.
To do it, they’ll have to hit the road and head into the desert to take on the Phoenix Mercury.
Phoenix has dominated this head-to-head, and my Sky vs. Mercury predictions and WNBA picks has that trend continuing Friday night from the Mortgage Matchup Center in Phoenix on May 15.
Sky vs Mercury prediction
Sky vs Mercury best bet: Mercury -4.5 (-110)
After tying for the worst record in the league a season ago, the Chicago Sky sit on top and has the second-best scoring defense in the league in the early going.
But how legit is their start?
They’ve beaten last year’s expansion team from Golden State, and opened the year with a win over Portland, who are in their debut season.
The Phoenix Mercury have won seven straight against Chicago, and they’re the top shooting 3-point team in the league, firing at a 41.3% clip.
Phoenix has averaged 90.3 points across those seven wins, and they burst the early-season good vibes in the Chi Friday.

Sky vs Mercury same-game parlay
Alyssa Thomas has cracked double-digit assists once in three games, but missing the Over two other times by three total assists. Last season, she had separate 15-assists and 10-assist games against Chicago.
And Kamilla Cardoso hasn’t been able to dominate the glass against the Mercury. In seven career games against Phoenix, she’s gone Under 10.5 boards each time, hitting 10 rebounds just once.
Sky vs Mercury SGP
- Mercury -4.5
- Alyssa Thomas Over 9.5 assists
- Kamilla Cardoso Under 10.5 rebounds
Sky vs Mercury first basket scorer: Kamilla Cardoso (+450)
The Sky big opened the scoring in Chicago’s season opener against Portland and dropped the first bucket in two meetings against the Mercury a season ago.
Sky vs Mercury odds
- Spread: Chicago +4.5 (-110) | Phoenix -4.5 (-110)
- Moneyline: Chicago +170 | Phoenix -205
- Over/Under: Over 166.5 (-110) | Under 166.5 (-110)
Sky vs Mercury trend
The Chicago Sky have lost 11 straight after winning as underdogs. Find more WNBA betting trends.
How to watch Sky vs Mercury
| Location | Mortgage Matchup Center, Phoenix, AZ |
| Date | Friday, May 15, 2026 |
| Tip-off | 10:00 p.m. ET |
| TV | ION |
Sky vs Mercury latest injuries
Sky: DiJonai Carrington (foot) ruled out.
Mercury: Sami Whitcomb (knee) and Monique Akoa Makani ruled out.
Find our latest WNBA injury reports.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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