Best WNBA Combo Picks & Predictions: Tuesday, Sept. 22

Kyle LaRusic - Betting Analyst at Covers.com
Kyle LaRusic • Betting Analyst 5+ years betting experience
Updated: Sep 22, 2026 , 04:28 PM ET • 4 min read

A showdown between two of the WNBA's top teams gets highlighted in our top combo plays.

wnba

Jan 01 • 12:00 AM ET
WNBA Combo Picks
Photo By - Reuters Connect. Caitlin Clark (22) passes past the defense of Minnesota Lynx forward Napheesa Collier

Five games take place in the W tonight, and we've created WNBA combo picks for the best matchups — including the Minnesota Lynx vs. Indiana Fever.

Find out which WNBA picks you need to make for Tuesday, Sept. 22.

WNBA combo picks today

For help understanding Kalshi probabilities, see our odds calculator.

Matchup Combo Kalshi
Probability
Sun Sun vs. Mystics Mystics

Mystics -18.5

Over 160.5

Kiki Iriafen 15+ points

5.90x
Lynx Lynx vs. Fever Fever

Caitlin Clark 20+ points

Napheesa Collier 20+ points

Over 187.5

4.53x

Percentages courtesy of Kalshi, one of the best prediction market apps.

Enjoying Covers content? Add us as a preferred source on your Google account Add as a preferred source on Google

Sun vs Mystics combo

Mystics -18.5

Over 160.5

Kiki Iriafen 15+ points

The Sun have been allowing opposing offenses to run wild lately, allowing 103.0 ppg over their last four contests. The Mystics have also been playing to the Over even with their sturdy defense, hitting the Over in six of their last eight games overall. The total is low here, making the Over a good combo play.

I'm also taking Washington's Kiki Iriafen to score 15+ points tonight. Iriafen is averaging 15.5 ppg and has hit the 15+ mark in eight of her last nine games. She should feast in a game where the Mystics could easily go for 100+ points as a team.

Check out Ed Scimia's full Sun vs. Mystics predictions.

Lynx vs Fever combo

Caitlin Clark 20+ points

Napheesa Collier 20+ points

Over 187.5

Napheesa Collier has scored 20-plus points in six of 14 games for the Minnesota Lynx, averaging 16.6 at home and 19.6 on the road. Leading scorer Olivia Miles is questionable with a calf injury, and her absence could mean additional offensive responsibilities for Collier. Even if Miles is available, I’ll still play this one up to 20.5, as the Fever rank 11th in defensive rating and allow the most PITP per game.

The Fever’s offense has clicked with Clark in the lineup, posting a 110.8 offensive rating and 90.4 ppg since she was drafted in 2024. Indiana leads the W in Over percentage at 61.9% and ppg at home (99.2). Minnesota ranks fourth in road scoring at 90 ppg.

Even if Miles is sidelined, Minnesota boasts more than enough firepower to put up points against a Fever defense surrendering 91.2 ppg at home. Play this to 189.5.

Check out Zak Hanshew's full Lynx vs. Fever predictions.

Start trading with Kalshi today!

Sign up now using our exclusive Kalshi promo code 'COVERS60' and trade $25 on any event contracts to get $60 — including the WNBA!

*Eligible U.S. locations only

How to trade WNBA combos today

Kalshi users can combine predictions for various markets for every WNBA game! Moneylines, spreads, and totals are fair game, as well as props for a player’s total points, assists, rebounds, 3-pointers made, and combo markets.

Prediction markets like Kalshi will set a projected total number for all the traditional markets and player stats, and users can predict whether the team will win or cover, if the total will go Over or Under, or whether players will reach certain statistical thresholds.

Combining predictions can increase a potential payday, but it also increases the risk level. If even one prediction in a three-leg combo is wrong, the whole thing is graded as a loss.

What is Kalshi?

Kalshi is a federally regulated platform for trading event outcomes on prediction markets. Traders can buy and sell simple, transparent contracts that settle based on the outcome of real-world events. Markets revolve around a yes/no proposition, with prices adjusting dynamically based on traders’ perceived probability that the event will occur. When the event concludes, if you are correct, the contract “honors” at a predetermined price; if you are incorrect, it expires at $0.

WNBA combos FAQs

What are the best WNBA combos today?

  • Sun vs. Mystics: Mystics -18.5/Over 160.5/Kiki Iriafen 15+ points
  • Lynx vs. Fever: Clark 20+ points/Collier 20+ points/Over 187.5

Where can I trade on WNBA combos?

Kalshi is a regulated prediction market that is federally legal in all 50 states.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Kyle LaRusic - Covers
Betting Analyst

Kyle LaRusic joined Covers in 2020 with a Holland College diploma in Journalism and a Mount Saint Vincent Degree in Public Relations. Stints at Amherst News and the Cape Breton Post helped sharpen his skills in a newsroom setting, while working for MSVU and Dalhousie’s athletic departments landed Kyle in his comfort zone.

Kyle has been an avid bettor for over five years, starting with just one Sports Interaction account before discovering both the beauty and importance of price shopping. bet365 and Pinnacle are his go to books, but accounts at 10+ sportsbooks give him an array of options. “Rusty” will bet on anything under the sun as long as there’s value and good reasoning behind it, but NHL and NFL are his two favorite leagues to watch and wager on — especially with friends.

Kyle’s biggest tip for any bettor is simple: gamble responsibly. Only bet what you’re willing to lose and make sure to install a proper bankroll method to keep track of your ROI. If you’re still dwelling on the amount you lost the next day, it’s time to decrease your spending.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo