Sodiq Yusuff vs Mairon Santos Predictions, Picks & Odds

Howard's prediction: Yusuff wins a marathon fight.

Danny Howard - Contributor at Covers.com
Danny Howard • Betting Analyst
May 17, 2025 • 12:10 ET • 4 min read
 Sodiq Yusuff moves in with a hit against Andre Fili.
Photo By - Imagn Images. Sodiq Yusuff moves in with a hit against Andre Fili.

Sodiq Yusuff is trying to rewrite the narrative after a pair of losses and prove he’s not prospect bait against young Mairon Santos.

Santos will step up the competition, while Yusuff hopes to avoid suffering a detrimental third loss in a row when the two clash at UFC Fight Night

UFC odds favor Santos at -150, with Yusuff returning as a +130 underdog in Las Vegas tonight.

Here are my best Yusuff vs. Santos predictions for Saturday, May 17.

Yusuff vs Santos prediction and best bet

Fight analysis
When Yusuff debuted in the UFC back in 2018, it didn’t take long for him to get noticed thanks to his high-volume striking and polished skill set. But it also didn’t take long for him to hit a roadblock, starting with a 2020 loss to Arnold Allen.

While some feel he’s hit his developmental ceiling, it may be too soon to relegate him to gatekeeper status, though this matchup against Santos suggests that’s the direction the UFC may be leaning.

Yusuff is moving up in weight to face Santos after being a solid top-15 featherweight contender. However, he’s on a two-fight skid for two very different reasons. Diego Lopes overwhelmed him early with a first-round knockout, and before that, Edson Barboza dropped him and outworked him, along with taking him down three times. At his best, Yusuff is a sharp boxer with good power and tight defense, but questions about his chin and focus remain, especially with the added variable of moving up a division.

Santos, the TUF 32 winner, is coming off a shaky split decision win over Francis Marshall, where he struggled with pace and gave up three takedowns. Statistically, Santos has a solid +1.77 striking differential, indicating he can land and defend efficiently. Still, Marshall was a grappler, and Kaan Ofli, whom Santos stopped in two rounds, isn’t the type of high-volume striker Yusuff is.

This fight may come down to who can apply the more effective pressure. Yusuff will look to slow Santos down with crisp, accurate shots and prevent him from settling into a rhythm. On the flip side, if Santos uses his size and athleticism early, he could break through Yusuff’s guard with a big shot and change the dynamic.

While Yusuff’s stock has dipped, Santos is still very green, and this is a step up in competition. I’m not ready to write Yusuff off yet. Yusuff is the pick in a minor upset.

Best bet analysis
This fight is likely to lean technical, to the dismay of fight fans. Yusuff won’t recklessly push forward against the naturally bigger Santos, and Santos is unlikely to go full throttle given the striking caliber of his opponent. Both prefer to keep fights standing, but neither is overly aggressive in forcing finishes. Yusuff tends to manage his output and avoids overcommitting, especially against bigger, longer fighters. My best bet is that the fight goes over 2.5 rounds.

Sodiq Yusuff vs Mairon Santos odds

Bet99
Method of Victory Yusuff Santos
To win outright +130 -150
To win by KO/TKO +625 +325
To win by decision +245 +155
To win by submission +1150 +1550
Draw +2500 +2500

Odds as of 5-17.

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Sodiq Yusuff vs Mairon Santos tale of the tape

Yusuff   Santos
32 Age 24
5-foot-9 Height 5-foot-7
Lightweight Weight Class Lightweight
71 inches Reach 72 inches
13-4-0 Record 16-1
6 Wins by KO 8
1 Wins by submission 0

Not intended for use in MA.
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Danny Howard - Covers.com
Betting Analyst

After a decade of covering all things boxing, from recapping the sport’s biggest fights to sharing behind-the-scenes details of the sweet science, Danny found himself immersed in sports betting, focusing on the sports he knows best. As a boxing and MMA contributor with seasoned experience from growing up around each sport, he can uncover the nuances and intangibles that can make the difference between victory and defeat.

Danny’s work has been mentioned on ESPN and USA Today, and he was a featured guest on The Esportz Network podcast, where he shared his combat sports insights. He is also a published author, with his novel And Stay Down! Boxing’s Worst Comebacks available on Amazon.

Danny is always on the lookout for the best odds and props when it comes to fight night, with Draft Kings and BetMGM being his go-to sites. Danny’s approach to finding value in the theater of the unexpected hinges on the fighters' recent form, especially when considering props.

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