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MLB Picks

Get free expert and computer MLB picks for every game on Sept. 29, 2026.

New Computer Picks powered by Odds Shark

Predicted Score

PHI logo
PHI
PHI

4.07 @ 4.70

ATL
ATL logo
ATL

Phillies vs Braves · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

PHI logo
PHI
PHI

4.07

+168

o6.5 -120

+1.5 -127

ATL logo
ATL
ATL

4.70

-190

u7.5 -179

-1.5 +125

Chi. White Sox @ Houston
Matchup Stats

Predicted Score

CHW logo
CHW
CHW

4.57 @ 4.44

HOU
HOU logo
HOU

White Sox vs Astros · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHW logo
CHW
CHW

4.57

+110

o8.0 -115

+1.5 -175

HOU logo
HOU
HOU

4.44

-122

u8.5 -118

-1.5 +163

Top Projection Yordan Alvarez o0.5 Total RBIs (+157)
o0.5+170
Boston @ NY Yankees
Matchup Stats

Predicted Score

BOS logo
BOS
BOS

4.11 @ 3.82

NYY
NYY logo
NYY

Red Sox vs Yankees · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

BOS logo
BOS
BOS

4.11

+122

o6.0 -125

+1.5 -175

NYY logo
NYY
NYY

3.82

-134

u6.5 -115

-1.5 +172

Top Projection Trevor Story o0.5 Total RBIs (+380)
o0.5+380
Chi. Cubs @ San Diego
Matchup Stats

Predicted Score

CHC logo
CHC
CHC

4.83 @ 4.51

SD
SD logo
SD

Cubs vs Padres · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHC logo
CHC
CHC

4.83

+110

o7.0 -115

+1.5 -190

SD logo
SD
SD

4.51

-124

u7.5 -124

-1.5 +175

Top Projection Austin Hays o0.5 Total RBIs (+300)
o0.5+302
Philadelphia @ Atlanta
Matchup Stats

Predicted Score

PHI logo
PHI
PHI

5.61 @ 4.72

ATL
ATL logo
ATL

Phillies vs Braves · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

PHI logo
PHI
PHI

5.61

--

--

--

ATL logo
ATL
ATL

4.72

--

--

--

Chi. White Sox @ Houston
Matchup Stats

Predicted Score

CHW logo
CHW
CHW

4.61 @ 4.88

HOU
HOU logo
HOU

White Sox vs Astros · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHW logo
CHW
CHW

4.61

--

--

--

HOU logo
HOU
HOU

4.88

--

--

--

Boston @ NY Yankees
Matchup Stats

Predicted Score

BOS logo
BOS
BOS

3.72 @ 4.05

NYY
NYY logo
NYY

Red Sox vs Yankees · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

BOS logo
BOS
BOS

3.72

--

--

--

NYY logo
NYY
NYY

4.05

--

--

--

Chi. Cubs @ San Diego
Matchup Stats

Predicted Score

CHC logo
CHC
CHC

5.06 @ 4.57

SD
SD logo
SD

Cubs vs Padres · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHC logo
CHC
CHC

5.06

--

--

--

SD logo
SD
SD

4.57

--

--

--

Philadelphia Phillies image thumbnail PHI @ Atlanta Braves image thumbnail ATL Tue, Sep 29 • 2:00 PM ET
Hits+Runs+RBIs
Trea Turner logo Trea Turner u1.5 Hits+Runs+RBIs (-160)
Best Odds
Pick made: an hour ago
Todd Cordell logo
Todd Cordell
Betting Analyst

Trea Turner did not fare well against high-end southpaws during the regular season.

He faced nine left-handed starters who ranked in the 70th percentile or better in xwOBA vs. right-handed hitters. Turner cleared 1.5 HRR in just one of those nine games, and averaged an underwhelming 0.7 HRR along the way.

Turner also hit .181 against fastballs and sliders thrown by lefties this year, which he'll see plenty of from Chris Sale.

Hits+Runs+RBIs
Ronald Acuna Jr. logo Ronald Acuna Jr. o1.5 Hits+Runs+RBIs (-120)
Best Odds
Pick made: an hour ago
Todd Cordell logo
Todd Cordell
Betting Analyst

Ronald Acuna Jr. led the Atlanta Braves with a .370 OBP, .406 wOBA, and .562 SLG over the final 25 games of the regular season.

He enjoyed plenty of success against lefties, trailing only Matt Olson in wOBA during that span. That’s noteworthy as he could see a couple of at bats against Jesus Luzardo out of the gate.

Acuna also has a career .310 average over 187 at-bats against Philadelphia Phillies relievers. 

View 15 Picks
Chicago White Sox image thumbnail CHW @ Houston Astros image thumbnail HOU Tue, Sep 29 • 5:00 PM ET
Total Home Runs
Munetaka Murakami logo Munetaka Murakami o0.5 Total Home Runs (+286)
Best Odds
Pick made: an hour ago
Colby Marchio logo
Colby Marchio
Contributor

Of Munetaka Murakami’s last 10 batted balls, six have had an exit velocity above 102.3 mph, with only three going for extra bases. Hitting the ball that hard will eventually find the bleachers.

With Astros opener AJ Blubaugh being 51% fastballs and Murakami feasting on them all season, this is a great spot to back the slugger at such a great price. 

Total
Chicago White Sox image thumbnail Houston Astros image thumbnail o8.5 (+103)
Best Odds
Pick made: 13 hours ago
Colby Marchio logo
Colby Marchio
Contributor

The White Sox and Astros are both swinging hot bats at the right time, making the market’s low-scoring expectation intriguing. Houston posted a 117 wRC+, .338 wOBA and .776 OPS during the final week of the regular season, while Chicago posted a 131 wRC+, .358 wOBA and .806 OPS. The White Sox’s pitching situation remains uncertain, and whoever takes the mound won’t exactly inspire confidence. Chicago’s bullpen also owns a 3.55 ERA and 4.59 xERA over its last 21 games while allowing a 42% hard-hit rate. With both offenses clicking, I’m expecting plenty of scoring in this matchup.

View 13 Picks
Boston Red Sox image thumbnail BOS @ New York Yankees image thumbnail NYY Tue, Sep 29 • 8:00 PM ET
Walks Allowed
Payton Tolle logo Payton Tolle u1.5 Walks Allowed (-145)
Best Odds
Pick made: 4 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Play up to 63%. Payton Tolle’s recent command has been excellent, with just 1.93 BB/9 over the last month. He’s issued only three walks across 13 innings against the Yankees this season, and New York’s aggressive approach against left-handed pitching should help keep the free passes down again.

Total Hits
Ben Rice logo Ben Rice o0.5 Total Hits (-153)
Best Odds
Pick made: 4 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Play up to 63%. Ben Rice closed the regular season swinging a hot bat, collecting six hits across his final four games. He’s also making consistently loud contact, posting a 61.5% hard-hit rate and 23.1% barrel rate over his last six contests. One hit is a very manageable target in Game 1.

View 16 Picks
Chicago Cubs image thumbnail CHC @ San Diego Padres image thumbnail SD Tue, Sep 29 • 10:00 PM ET
Strikeouts Thrown
Michael King logo Michael King o4.5 Strikeouts Thrown (-120)
Best Odds
Pick made: 4 minutes ago
Neil Parker logo
Neil Parker
Betting Analyst

The Chicago lineup will be facing King for the first time, and the go-to righty has fanned five or more batters in four of his past six starts while holding opposing hitters to a minuscule .295 wOBA and 7.0 barrel percentage. As a result, I’m anticipating King pitching deep enough into the series opener to pick up at least five strikeouts tonight and recommend this prop to -135.

Total
Chicago Cubs image thumbnail San Diego Padres image thumbnail o7.5 (+107)
Best Odds
Pick made: 31 minutes ago
Joe Osborne logo
Joe Osborne
Senior Betting Analyst

San Diego ranks second in OPS over the past two weeks and first against lefties. The Padres have a combined .839 OPS in 108 at-bats against Matthew Boyd and smacked him around him for eight earned runs in two games this season. Chicago’s lineup has a combined .906 OPS against Michael King, and the Cubs have been especially dangerous on the road and against righties. Both bullpens have been average at best lately, and the Over hit in five of six regular-season meetings.

View 15 Picks

What Is An MLB Computer Pick?

MLB picks are bet suggestions based on our computer's assessment of the game. Tons of betting data goes into a computer pick, including pitching matchups, injury reports, analytics, and even recent betting trends.

How To Use MLB Computer Picks

You can use the tables above to help with your bets during the MLB season. The first section includes free, computer-generated picks for daily Major League Baseball games. Baseball bettors can choose to follow the computer, fade the computer, or simply use our computer picks as one element of their betting strategy.

This page also tees up access to deeper betting trends. For example, if a club's run line is favored, you can check their ATS trends, potentially opening up some quality underdog bets.

If you're ready to get started with MLB betting, visit our dedicated page highlighting the best MLB betting sites.

Moneyline

This is the most common and easiest wager for a bettor to make when it comes to MLB picks. Basically, to win an MLB moneyline pick, you just have to choose which team will win the game.

It's simple: if you bet the White Sox moneyline over the Red Sox and Chicago wins, you win your bet.

Run line

The run line is another name for a point spread that you may be more familiar with in NBA and NFL betting. A point spread varies in the NFL and NBA from as little as 0.5 points up to double-digit spreads. A baseball run line is almost always a 1.5-point spread.

The favorite will be -1.5 while the underdog will be +1.5. At the end of the game, if you take away 1.5 runs from the favorite or add 1.5 runs to the underdog and they end up winning the game, you win your MLB pick against the spread.

Totals (Over/Under)

Another common wager is to bet on the total in baseball, which is a bet on the total runs scored in the baseball game. You are simply choosing whether the final score will be Over or Under that total. Betting the Over/Under on a matchup is a great way to get started in MLB score predictions.

Free Computer Picks by Odds Shark

More MLB Picks & Betting Tools

NRFI/YRFI MLB Picks

A new and emerging MLB betting market is the NRFI/YRFI bet. These are quick-hitters in which you make a wager on the O/U total of the first inning, typically set at 0.5 runs. Thus, the bet is coined as No Run First Inning or Yes Run First Inning. No need to wait a couple of hours to cash a bet when it could be done in 20 minutes or less.

First Five Innings MLB Picks

The above options, moneyline, run line, and Over/Under, can also be placed on the first five innings of a game rather than the full game. Many experienced bettors will use this approach because, typically, this will take bullpens out of the equation and make your job researching the game easier. After all, you can just focus on the starting pitchers.

MLB Picks And Parlays

If you want to combine multiple games into one mega wager, you may consider making a parlay bet. A parlay is when you pick two or more MLB games on one single betting ticket, which will increase the payout of your bet.

But it also comes with more risk, as each of those MLB picks must hit for your ticket to pay out. Our parlay calculator is a great tool to find out what your potential payout would be.

If you're looking for more MLB picks content, check out our consensus picks and prop bets pages to get your fix. While you're at it, head over to our MLB promos page to get the best bang for your buck.

MLB Player Props

Player props are a great way to hone in on an individual matchup for a game. These types of wagers will be individualized for a player: Will Shohei Ohtani hit a home run? Will Gerrit Cole get seven strikeouts? Will Paul Skenes allow two earned runs?

You simply choose whether this outcome will happen or not. Keeping up to date on daily pitching matchups and batters on a hot streak can give you a huge boost when placing player prop bets.

MLB Futures Picks

Lastly, prior to the season and even throughout the season, you can place futures bets on all the long-term awards and outcomes. You can lock in an MLB pick on who will win their division, which squad will win the World Series, or even who will win the Rookie of the Year, MVP, or Cy Young.

MLB Free Picks FAQs

When do we release our MLB picks?

Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.

What kinds of MLB picks do we make?

Covers provides free MLB picks covering many markets, including run lines, totals, moneylines, player props, and more.