Southampton vs Brentford Picks and Predictions: Tuesday Night Special on the South Coast

Southampton hosts Brentford as the lone game on Tuesday's Premier League Schedule after Everton vs. Leicester was postponed. This has all the makings of a low-scoring affair, and we feel a draw is more likely than a definitive winner in our betting picks.

Last Updated: Jan 10, 2022 2:36 PM ET Read Time: 4 min
Mohammed Salisu Southampton Premier League
Photo By - USA TODAY Sports

With Everton vs. Leicester postponed, we’re now left with just one Premier League game on Tuesday, but Southampton vs. Brentford could be a lot more fun than expected with both sides enjoying strong seasons.

Just two points and two positions separate Southampton and Brentford in the Premier League table, but that can all change very quickly. Don’t miss our Southampton vs. Brentford tips and predictions.

Southampton vs Brentford match odds

Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.

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Southampton vs Brentford betting tips

Predictions made on 1/10/2022 at 2:20 p.m. ET.
Click on each prediction to jump to the full analysis.

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Southampton vs Brentford game info

Location: St. Mary's Stadium, Southampton, England
Date: Tuesday, January 11, 2022
Time: 2:45 p.m. ET
TV: DAZN, Peacock Premium, fubo TV, Sling Blue, Hulu + Live TV

Southampton vs Brentford betting preview


With the game kicking off at 7:45 p.m. local time, we’ll see it played under floodlights with temperatures in the mid-40s. Fortunately for the fans, it’s likely to be dry with the rain falling earlier in the day, which will give us a nice, speedy pitch suitable for great passing.


Southampton: Alex McCarthy (Out), Jack Stephens (Out), Lyanco (Out), Nathan Tella (Out), Valentino Livramento (Out), Kyle Walker-Peters (Out), Will Smallbone (Out).
Brentford: Josh Dasilva (Out), David Raya (Out).

Southampton vs Brentford predictions

Our predictions are compiled from the analysis of the spread and total and are indications of where we are leaning for this game.
Our best bet is the play that we like the most for this game, which we would actually put some of our bankroll behind.

The ongoing health crisis in the UK has meant that one of Tuesday’s Premier League games, Everton vs. Leicester has been postponed, which means the eyes of the world will be focused on Saint Mary’s Stadium where Southampton will be welcoming Brentford to town.

Just two positions and two points separate the teams in the Premier League with the promoted Bees sitting 12th on 23 points and the hosts in 14th. Both teams started the season with their eyes on the relegation zone but are now some way clear of it and dreaming of a mid-table finish with European spots likely out of their reach.

For Brentford, it has been a triumphant first season in the Premier League. Thomas Frank has coached a well-put-together squad into a team that has stuck to its principles and held true to the style of play that saw it heralded as the entertainers of the Championship in previous years. From their impressive victory over Arsenal on opening day, we could tell it would be a special season for the Bees, and their fans will be overjoyed with how they’ve played throughout.

It’s no secret they’ve been built with analytics playing a key role in player recruitment. Despite the advantage that great scouting can give a team it takes a good coach to gel those players together and to get them ready for life in the Premier League, the biggest, fastest, strongest league in the world.

Frank's counterpart at Southampton, Ralph Hasenhüttl, has enjoyed media plaudits since arriving in the South Coast after a spell in charge of RB Leipzig. The club has made some shrewd moves in the transfer market this year with Adam Armstrong playing well up front, even if he hasn’t replaced the goals of former star Danny Ings. The signing of rightback Valentino Livramento from Chelsea has also been inspired but the talented youngster will be missing Tuesday’s game. That injury to Livramento, as well as the absence of Kyle Walker-Peters, could see the club’s best player, James Ward-Prowse move from central midfield to right back. That’s a big loss to the engine room of the team where we’ll likely see Oriol Romeu and Ibrahima Diallo tasked with stopping Brentford’s midfielders.

Southampton haven’t been in great form, winning just one of their past five Premier League games, whereas Brentford's won two of their last five. This has the makings of a low-scoring game in either direction or perhaps even a draw.

The draw looks like a very appetizing bet given that Southampton have drawn their past three games at St Mary’s Stadium in the league and the visitors from Brentford haven't won an away game in any of their last five attempts.

Prediction: Draw (+240)

You’re going to want to back the Under. In nine home games in the Premier League, Southampton have only had Over 2.5 goals on two occasions. They’ve also got a good record against Brentford, with there being Under 2.5 goals in their last three home meetings.

Not only do the stats suggest that Southampton’s home form means we’re more likely to see Under 2.5 land, but so do Brentford’s stats, too. There have been Under 2.5 goals scored in 55.6% of their trips on the road this season with Thomas Frank’s team taking a slightly more defensive approach.

Prediction: Under 2.5 total goals (-110)

Southampton have had two red cards in their past two matches - including their victory in the FA Cup this past weekend - and four total on the season. That sounds like a team that doesn't have the discipline it should and that various card markets are particularly interesting for this game.

Stuart Atwell will be taking charge of the game and the Englishman has dished out 37 yellows in 11 Premier League games this season, an average of 3.36 per game. There are a number of players who leap out as potential picks to get a booking, with midfielder Oriol Romeu (+225) a standout choice, having accrued five this season in 19 starts.

Despite this, we’ll be backing Mohammed Salisu, who is making his return from a ban, to pick up a booking. The Ghanaian has picked up seven already this term and is susceptible to moments of rash play. At +270, he’s a great price, and you could even wager on both of the players in a same-game parlay.

Pick: Mohammed Salisu to be booked (+270)

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