Jaguars vs Texans Predictions - Early Picks & Odds for Week 10

The Texans lost by a field goal against the Broncos in their last outing, but they'll get right in Week 10 against the Jags.

Ryan Gilbert - Contributor at Covers.com
Ryan Gilbert • Betting Analyst
Nov 4, 2025 • 14:07 ET • 4 min read
Houston Texans quarterback C.J. Stroud (7) runs with the ball during the fourth quarter against the San Francisco 49ers at NRG Stadium.
Photo By - Imagn Images. Houston Texans quarterback C.J. Stroud (7) runs with the ball during the fourth quarter against the San Francisco 49ers at NRG Stadium.

The Jacksonville Jaguars look to make it two wins in a row when they visit the Houston Texans in Week 10.

The Jaguars went into Las Vegas and came away with a 30-29 win after the Raiders failed on their two-point try to win the game in overtime. Meanwhile, Houston dropped an 18-15 decision to Denver, falling to 3-5 on the year.

My Jaguars vs. Texans predictions and NFL picks expect Houston to bounce back at home on November 9.

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Jaguars vs Texans predictions

Here are our early thoughts on the spread and total for this week’s game. We will have a full game preview (with a best bet and SGP) later in the week.

Early Jaguars vs Texans spread pick: Texans -1.5

-104 at FanDuel

The Jacksonville Jaguars have fallen off in recent weeks, with two straight losses before the bye. The Jags were lucky to get the win in Las Vegas last week, in game that could have gone either way.

The Houston Texans started the season 0-3 but are 3-2 since, with both losses coming by one score. Houston's defense also just held the Broncos to 18 points, with Denver needing a game-winning field goal to secure the victory.

If Houston can finally put points on the board, its defense should have no trouble slowing down the ever-mediocre Trevor Lawrence.

This game is priced fairly accurately, but I’m inclined to go with the home team here in what is essentially a must-win game for Houston.

Early Jaguars vs Texans total pick: Under 38.5

-110 at FanDuel

These teams combined for just 27 points in their first meeting, and 14 of those came in the fourth quarter. These are two teams that have been struggling to score while also having enough power on defense to stay in the game.

Aside from an absurd fourth-quarter burst, the Jags' game against Vegas was a total snooze fest. Don't let the 30-29 final fool you. Jacksonville has played to an O/U record of 4-4 this season, with two of these three Unders coming in the last three weeks.

Meanwhile, the Texans have gone Over in just two of eight games this season, and I see a similarly low-scoring affair similar to the first matchup this time around.

Jaguars vs Texans odds

  • Jaguars vs. Texans spread: Texans -1.5
  • Jaguars vs. Texans moneyline: Jaguars -102, Texans -116
  • Jaguars vs. Texans Over/Under: 38.5

How to watch Jaguars vs Texans

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Ryan Gilbert - Covers
Betting Analyst

Ryan Gilbert brings the passion and pain of being a Philadelphia sports fan. After graduating from Monmouth University with a finance degree, he now uses his statistical background to find inefficiencies in betting markets. With past stops at NHL.com, NBC Sports, and currently at Covers, Ryan's hot picks blend well with the cold ice of a hockey rink.

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