The Patrick Mahomes-less Kansas City Chiefs, who are already eliminated from playoff contention, will head to Nashville on Sunday to face the Tennessee Titans at Nissan Stadium.
Kansas City’s defense is still solid, and my Chiefs vs. Titans predictions are eyeing them to contain Cam Ward in Week 16.
Read more in my NFL picks for December 21.
Chiefs vs Titans prediction
Chiefs vs Titans Best bet: Cam Ward Under 179.5 passing yards (-114)
Cam Ward has definitely had his road bumps in Year 1 after going first overall in April’s NFL draft.
The Miami product has thrown for just 2,638 yards and 11 touchdowns against seven interceptions. Playing for a struggling franchise like the Tennessee Titans hasn’t been easy.
The quarterback has cashed the Under in passing yards in three straight appearances, finishing with 170 yards through the air last weekend in a loss to the San Francisco 49ers.
While the Kansas City Chiefs may be missing the playoffs, they’re still fifth in fewest total yards allowed, and Andy Reid’s pass defense is also 13th in fewest yards allowed through the air.
Ward doesn’t have a lot of weapons to work with, and he hasn’t cashed the Over since late November. The Chiefs are still motivated to finish the campaign on a high note, and I believe they will keep Ward under wraps in Week 16.
Enjoying Covers content? Add us as a preferred source on your Google account
Chiefs vs Titans same-game parlay
Travis Kelce has had a couple of crucial drops this season, but he’s still one of the Chiefs’ top pass-catchers, reeling in 67 receptions for 797 yards and five touchdowns. Kelce has cashed the Over in receiving yards in six of his last eight, and two of his last three.
Kareem Hunt has proven to be reliable this year at running back for K.C., but after a quiet performance in Week 15, his total is incredibly low here.
Hunt was limited to only six carries for 12 yards, but before that, he hit the Over in rushing yards in six straight games, running for at least 30 yards in each of those contests.
Chiefs vs Titans SGP
- Cam Ward Under 179.5 passing yards
- Travis Kelce Over 43.5 receiving yards
- Kareem Hunt Over 27.5 rushing yards
Our big-ticket SGP: Kelce hits paydirt
Kelce has just one TD in his last three games, but four of his five scores this season have come on the road.
Chiefs vs Titans SGP
- Cam Ward Under 179.5 passing yards
- Travis Kelce Over 43.5 receiving yards
- Kareem Hunt Over 27.5 rushing yards
- Travis Kelce anytime TD
Chiefs vs Titans odds
- Spread: Chiefs -3 | Titans +3
- Moneyline: Chiefs -168 | Titans +142
- Over/Under: Over 37.5 | Under 37.5
More NFL picks and odds from Covers
Chiefs vs Titans trend to know
The Titans have only hit the moneyline in 4 of their last 20 games (-10.42 Units / -46% ROI). Find more NFL betting trends for Chiefs vs. Titans.
How to watch Chiefs vs Titans
| Location | Nissan Stadium, Nashville, TN |
| Date | Sunday, December 21, 2025 |
| Kickoff | 1:00 p.m. ET |
| TV | CBS |
Chiefs vs Titans latest injuries
Chiefs vs Titans weather
Monitor gametime conditions with our live NFL weather info and learn how weather impacts NFL betting.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
