There’s a loaded slate of college football games this weekend, beginning on Friday and continuing throughout Saturday.
Whether it’s a rivalry game or one that has implications for the College Football Playoff, there are plenty of pivotal matchups on the board — and we have you covered with moneyline college football picks for each of the top Week 14 games.
Week 14 college football moneyline picks
| Matchup | Pick |
|---|---|
 Mississippi vs  Mississippi State |
(+225) |
 Georgia vs  Georgia Tech |
(-620) |
 Texas A&M vs  Texas |
(-120) |
 Arizona vs  Arizona State |
(+106) |
 Miami vs  Pittsburgh |
(-255) |
 Ohio State vs  Michigan |
(-410) |
 Clemson vs  South Carolina |
(+116) |
 Vanderbilt vs  Tennessee |
(+126) |
 Oregon vs  Washington |
(-260) |
 LSU vs  Oklahoma |
(-400) |
 Alabama vs  Auburn |
(-230) |
Lines courtesy of FanDuel.
Expert Week 14 CFB moneyline picks
Mississippi vs Mississippi State: Mississippi State (+225)
Let’s kick things off with the Egg Bowl, where we’re going with Mississippi State to pull off the upset. To say there are a lot of distractions around the No. 7 Mississippi program right now would be a massive understatement. The Rebels have an unreliable run defense (120th in EPA per rush) and have played down to their level of competition numerous times (Kentucky, Arkansas, Washington State), which could prove troublesome in a heated rivalry game.
Georgia vs Georgia Tech: Georgia (-620)
No. 4 Georgia has only improved as the year has progressed, winning its last three games by a combined score of 111-34. That’s a stark contrast to No. 23 Georgia Tech, which has lost two of its last three games, and the lone win was an unimpressive 36-34 nail-biter against lowly Boston College. Tech’s defense has fallen apart, surrendering 510.7 yards per game in its last three, whereas Georgia’s stop unit is playing its best ball of the season.
Texas A&M vs Texas: Texas A&M (-120)
This one could be a trendy upset pick as No. 16 Texas has the talent to win this game outright, and No. 3 Texas A&M likely has a playoff bid locked up regardless of the outcome, hence the short number. Still, the Longhorns have been bad on offense all year (100th in success rate) and have been bad on defense lately (420+ total yards surrendered in three of their last four games). A&M has been a buzzsaw other than the first half against South Carolina.
Arizona vs Arizona State: Arizona State (+106)
In what’s an overlooked ranked-on-ranked matchup in the Big 12, No. 25 Arizona and No. 20 Arizona State meet in a game with Big 12 title race implications for the Sun Devils. This game has razor-thin margins on paper, but by now, I’ve learned to trust Kenny Dillingham. The Sun Devils have averaged 6.7 yards per play or better in two of their last three games despite being on a backup quarterback (Jeff Sims), and they should be able to run the ball against Arizona’s leaky rush defense (113th in rushing success rate) and rely on their nasty defense.
Miami vs Pittsburgh: Miami (-255)
No. 12 Miami still needs to win and rack up style points to boot, should the Hurricanes hope to have a chance of reaching the playoffs. No. 22 Pittsburgh isn’t a pushover, but we just saw the Panthers be uncompetitive against an elite team two weeks ago in a 37-15 loss to Notre Dame. Miami is playing lights out defensively (10th in EPA per play) and should be able to throw the ball in this matchup.
Ohio State vs Michigan: Ohio State (-410)
Yes, yes — I’m aware that the Wolverines have won four consecutive in this rivalry. It’s been discussed enough, so I’ll focus on the actual game, where No. 1 Ohio State is a juggernaut on both sides of the ball (first in offensive success rate, third in defensive EPA per play). No. 15 Michigan isn’t a pushover, but the Wolverines aren’t elite on offense (35th in EPA per play) or defense (64th in success rate), have a true freshman quarterback, and two banged-up running backs. Sherrone Moore’s squad has benefitted from a soft schedule en route to a 9-2 record, but let’s not forget they were uncompetitive against USC and Oklahoma in their two toughest games of the year.
Clemson vs South Carolina: Clemson (+116)
Clemson and South Carolina are a combined 10-12 this season, but the Palmetto Bowl still carries plenty of intrigue. The Tigers haven’t lost in Columbia since 2014, and there isn’t enough deperating these teams for me to buy South Carolina as a favorite. Clemson has won three straight and will be able to throw the ball (South Carolina 110th in passing success rate allowed), and while the Gamecocks will have plenty of moments, they haven’t been able to string together four quarters of impressive football all year.
Vanderbilt vs Tennessee: Vanderbilt (+126)
No. 14 Vanderbilt is no joke. Diego Pavia and this offense are firing on all cylinders (first in EPA per play) and will be able to find plenty of room against No. 19 Tennessee’s defense (81st in success rate). The Vols haven’t beaten a good team all year, and yet they're favored to do so in Week 14 — not so fast!
Oregon vs Washington: Oregon (-260)
This is far from a cakewalk for No. 6 Oregon, playing on the road against an 8-3 rival to cap the regular season. Still, the Ducks have been so impressive lately that I’d take them to pull off the win even if Washington’s two best skill position players (Jonah Coleman, Denzel Boston) weren’t hobbled by injuries, which they are.
LSU vs Oklahoma: Oklahoma (-400)
No. 8 Oklahoma doesn’t have a good enough offense to trust them in any game, but I’ll still take the Sooners to pull off the win against an LSU team that has lost three of its last five games and is on major “quit watch” with little to fight for. All the pressure is on the Sooners in this matchup, but it helps when you have an elite defensive line (second in line yards, second in front seven havoc) going up against a woeful LSU offensive line (128th in line yards, 130th in stuff rate).
Alabama vs Auburn: Alabama (-230)
Boy, wouldn’t it be funny if Auburn pulled off something incredible at Jordan-Hare to dash its rival’s playoff hopes? It sure would be, but that doesn’t mean that it will happen. Auburn’s offense is no good (66th in EPA per play) and its secondary has struggled all year (112th in passing success rate), which makes this a difficult matchup against Ty Simpson & Co.
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My college football moneyline record is X-X this season for +X.XX units.
Odds are correct at the time of publishing and are subject to change.
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